A5001665684- Advanced Photocatalysis Techniques
- Advanced biosensing and bioanalysis techniques
- Lipid Membrane Structure and Behavior
- Electrochemical Analysis and Applications
- Advanced battery technologies research
- Electrocatalysts for Energy Conversion
- Luminescence Properties of Advanced Materials
- Protein Structure and Dynamics
- Glycosylation and Glycoproteins Research
- Hydrology and Watershed Management Studies
- Flood Risk Assessment and Management
- Biosensors and Analytical Detection
- Receptor Mechanisms and Signaling
- Spectroscopy and Quantum Chemical Studies
- Mass Spectrometry Techniques and Applications
- Advanced Nanomaterials in Catalysis
- Environmental Monitoring and Data Management
- HIV/AIDS drug development and treatment
- Perovskite Materials and Applications
- Hydrological Forecasting Using AI
- Microwave Dielectric Ceramics Synthesis
- HER2/EGFR in Cancer Research
- Supercapacitor Materials and Fabrication
- Arsenic contamination and mitigation
- Reservoir Engineering and Simulation Methods
Hunan Normal University
2017-2025
Hunan Provincial Center for Disease Control and Prevention
2022-2025
Wuhan Institute of Physics and Mathematics
2024
Chinese Academy of Sciences
2010-2024
Shanghai Institute of Materia Medica
2010-2013
Lanzhou University
2006
Cholesterol, an abundant membrane component in both lipid rafts and caveolae of cell membrane, plays a crucial role regulating the function organization various G-protein coupled receptors (GPCRs). However, underlying mechanism for cholesterol-GPCR interaction is still unclear. To this end, we performed series microsecond molecular dynamics (MD) simulations on β2-adrenergic receptor (β2AR) presence absence cholesterol molecules POPC bilayer. The unbiased MD simulation system with...
A photoelectrochemical enzymatic biofuel cell consisting of a (methyl violet/Au nanoparticles) 25 /fluorine-doped tin oxide (FTO) photoanode without conventional semiconductor(s) and bilirubin oxidase/CuCo 2 O 4 /FTO bio-photocathode is developed.
Ion mixtures are prevalent in both cytosol and the exterior of a plasma membrane with variable compositions concentrations. Although abundant MD simulations have been performed to study effects single ion species on structures lipid bilayers, our understanding influence mixture membranes is still limited; for example, competition mechanism different ions binding lipids not clearly addressed yet. Here, microsecond were carried out Ca(2+), Mg(2+), Na(+), K(+)...
Eu2+-activated Ba2ZnS3 has been reported as a red phosphor with broad emission band peaking at 650 nm under blue excitation for white-LED. In this study, Ba2ZnS3:Eu2+, X– (X = F, Cl, Br, I) phosphors doped halide ions were prepared by traditional high-temperature solid-state reaction. Phase identification of powders was performed X-ray powder diffraction analysis, confirming the existence single-phase crystals without dopant. The corresponding spectra showed an additional in green region 550...
Ion−membrane interactions are essential to the regulation of cell functions. While numerous molecular dynamics (MD) simulations have been carried out study effects ions on neutral lipid bilayers, few conducted anionic bilayers. Moreover, there is a lack long-time simulations. Here, submicrosecond MD were performed investigate pure cations (K+, Na+, and Ca2+, respectively) palmitoyloleoylphosphatidylglycerol (POPG) bilayer first. The results reveal how K+, Ca2+ influence structure In general,...
ErbB4, a receptor tyrosine kinase of the ErbB family, plays crucial roles in cell growth and differentiation, especially development heart nervous system. Ligand binding to its extracellular region could modulate activation process. To understand mechanism ErbB4 induced by ligand binding, we performed one microsecond molecular dynamics (MD) simulations on (ECR) with without endogenous neuregulin1β (NRG1β). The conformational transition ECR-ErbB4/NRG1β complex from tethered inactive...
A Au-stained Au nanoparticle (Au
An effective coupling of an In 2 O 3 /WO type-II heterojunction with CdS quantum dots-polydopamine nanospheres labeling achieves the high-performance photoelectrochemical sandwich immunoassay CYFRA21-1.
Abstract Accurate monitoring of river discharge variations is essential for managing floods and droughts understanding the response global systems to climate change. Remote sensing (RSQ) offers a timely efficient alternative widespread monitoring, particularly in ungauged areas. Current methods often struggle with accuracy, especially when estimating width narrow rivers from medium‐resolution images. We first observe that, although variation can be challenging satellite imagery, still...
Shrubs are typical vegetation on the Qinghai – Tibet Plateau, and their spatial distribution pattern is crucial for understanding regional ecological environment. Existing global land cover products cannot represent shrubs well in this area, relationship between corresponding environmental factors still unclear. In study, using Dogxung Zangbo River Basin as an example, Sentinel-2 images were applied to estimate shrub fraction image, random forest regression model trained with samples...
S5a is a critical component of proteasome and carries ubiquitin recognition function. Previous nuclear magnetic resonance (NMR) experiments have shown that K48-linked diubiquitin binds to through major minor conformational species. Molecular dynamics simulations been performed on S5a:K48-linked complex extracted from both species investigate the essential dynamic behaviour receptor in free with diubiquitin. It shows structures as well S5a:diubiquitin are very mobile during simulations, which...