A5001837719- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiovascular and Diving-Related Complications
- Gastrointestinal Tumor Research and Treatment
- Mechanical Circulatory Support Devices
- Gallbladder and Bile Duct Disorders
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal disorders and treatments
- Colorectal Cancer Screening and Detection
- Aortic Disease and Treatment Approaches
- Colorectal Cancer Surgical Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Liver Disease and Transplantation
- Transplantation: Methods and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Esophageal and GI Pathology
- IgG4-Related and Inflammatory Diseases
- Cardiac Arrest and Resuscitation
- Appendicitis Diagnosis and Management
- 14-3-3 protein interactions
- Congenital Diaphragmatic Hernia Studies
- Neuroendocrine Tumor Research Advances
Yonsei University
2015-2024
Severance Hospital
2022-2024
Asan Medical Center
2002-2023
Ulsan College
2002-2023
University of Ulsan
2004-2023
Kyung Hee University Medical Center
2022
Korea Advanced Institute of Science and Technology
2009-2021
Korea Institute of Radiological and Medical Sciences
2017-2020
Yonsei University Health System
2020
Samsung Medical Center
2019
To describe the anatomical variation occurring in intrahepatic bile ducts (IHDs) terms of their branching patterns, and to determine frequency each variation.The study group consisted 300 consecutive donors for liver transplantation who underwent intraoperative cholangiography. Anatomical IHDs was classified according pattern right anterior posterior segmental duct (RASD RPSD, respectively), presence or absence first-order branch left hepatic (LHD), an accessory duct.The anatomy typical 63%...
Abstract Background and objectives The effects of isolated metastatic node dissection in the para‐aortic region have not been established colorectal cancer (CRC). authors undertook to evaluate role lymph (PALN) CRC with PALN metastasis. Methods Between January 1993 March 2006, 24 patients underwent for metastasis from CRC. Patients distant metastases other than PALNs, or nodal above celiac axis were excluded. control group was composed 53 below level renal hilum that surgically removed....
PURPOSE: To determine the spectral Doppler ultrasonographic (US) findings that would indicate hepatic vein stenosis after living donor liver transplantation (LDLT). MATERIALS AND METHODS: The authors retrospectively reviewed postoperative US images of veins in 113 consecutive patients who underwent LDLT. was performed 1–25 times (mean, 5.2 times) during 1–433 days Nineteen were inadequate for analysis excluded; thus, 94 (72 male and 22 female patients; mean age, 40 years) included study....
Abstract On October 2020, the US Food and Drug Administration (FDA) approved remdesivir as first drug for treatment of coronavirus disease 2019 (COVID‐19), increasing prescriptions worldwide. However, potential cardiovascular (CV) toxicities associated with remain unknown. We aimed to characterize CV adverse reactions (ADRs) using VigiBase, an individual case safety report database World Health Organization (WHO). Disproportionality analyses CV‐ADRs were performed reported odds ratios...
The study was conducted, with institutional review board approval and informed patient consent, to assess the feasibility diagnostic effectiveness of three-dimensional direct multi-detector row computed tomographic (CT) cholangiography for determining extent bile duct invasion by hilar cholangiocarcinoma. Eleven patients underwent contrast material-enhanced CT primary secondary biliary confluence levels then surgical resection. In most patients, tolerable yielded excellent or good...
Pulmonary arterial hypertension (PAH) related to an atrial septal defect (ASD) poses a challenge transcatheter closure of ASD (tcASD). We aimed determine the predictors for remaining PAH (rPAH) post-tcASD. This retrospective study was conducted at single tertiary university hospital. Adult patients with and were divided into three groups according pulmonary vascular resistance (PVR). Normalization systolic pressure (PASP) defined as estimated right ventricular < 40 mmHg determined using...
To evaluate whether computed tomography (CT) accurately depicted gastrointestinal tract involvement in peripheral T-cell lymphoma (PTCL).CT scans were retrospectively reviewed 14 patients with pathologically proved PTCLs of the for following considerations: sites, patterns (ie, morphologic features, bowel wall thickness or mass size, and contrast enhancement pattern), ancillary findings at other sites lymphadenopathy, perforation, organs).PTCL involved stomach three patients, small intestine...
Isolated gastric IgG4-related disease (IgG4-RD) is a very rare tumefactive inflammatory condition, with only few cases reported to date. A 48-year-old woman was incidentally found have subepithelial tumor in the stomach. Given presumptive diagnosis of gastrointestinal stromal or neuroendocrine tumor, she underwent wedge resection. The lesion vaguely nodular and mainly involved submucosa proper muscle layer. Microscopically, all classical features type I autoimmune pancreatitis including...
Objective: To investigate the characteristic radiologic features of post-ischemic stricture, which can then be implemented to differentiate that specific disease from other similar bowel diseases, with an emphasis on computed tomography (CT) features.Materials and Methods: Eight patients a diagnosis ischemic disease, who were also diagnosed postischemic stricture basis clinical or pathologic findings, included.Detailed data was collected available electronic medical records.Two radiologists...
Over the last decade, extracorporeal membrane oxygenation (ECMO) use in critically ill children has increased and is associated with favorable outcomes. Our study aims to evaluate current status of pediatric ECMO Korea, a specific focus on its volume changes survival rates based diagnostic indications.
Abstract Background Pulsta valve is increasingly used for percutaneous pulmonary implantation (PPVI) in patients with a large native right ventricular outflow tract (RVOT). This study aims to elucidate the outcomes of within RVOT and assess its adaptability various main artery (PA) anatomies. Methods A multicenter retrospective included 182 moderate severe regurgitation who underwent PPVI valves® between February 2016 August 2023 at five Korean Taiwanese tertiary referral centers. Results...
Class III receptor tyrosine kinase (RTK) inhibitors targeting mainly FLT3 or c-KIT have not been well studied in lung cancer. To identify a small molecule potentially class RTK, we synthesized novel compounds and identified 5-(4-bromophenyl)-N-(naphthalen-1-yl) oxazol-2-amine (AIU2001) as RKT inhibitor. In an vitro profiling assay, AIU2001 inhibited the activities of FLT3, mutated FLT4, proliferation NSCLC cells vivo. induced DNA damage, reactive oxygen species (ROS) generation, cell cycle...
PURPOSE: To compare the accuracy of upper gastrointestinal (UGI) series and endoscopic examination in diagnosis localization scirrhous gastric carcinoma. MATERIALS AND METHODS: Seventy-two patients with pathologically proved carcinoma surgical specimens were included. Preoperative reports at UGI examination, which included impressions on location extent tumor, compared pathology reports, preoperative was calculated. Two radiologists retrospectively reviewed appearance mucosa series. RESULTS:...
A phase II study of preoperative chemoradiation (CRT) with S-1 plus oxaliplatin in patients locally advanced rectal cancer was conducted. The total radiotherapy dose 50.4 Gy. Chemotherapy consisted 50 mg/m(2) on days 1, 8, 22 and 29 80 per day 1-14 22-35. tumor apparent diffusion coefficient (ADC) measured using diffusion-weighted magnetic resonance imaging (DW-MRI) before after CRT. Total mesorectal excision performed within 6 ± 2 weeks. primary end-point the pathological complete response...
Although MASTL (microtubule-associated serine/threonine kinase-like) is an attractive target for anticancer treatment, inhibitors with antitumor activity have not yet been reported. In this study, we presented a novel inhibitor, MKI-1, identified through in silico screening and vitro analysis. Our data revealed that MKI-1 exerted radiosensitizer activities vivo models of breast cancer. The mechanism action occurred increase PP2A activity, which subsequently decreased the c-Myc protein...
Percutaneous pulmonary valve implantation (PPVI) is used to treat stenosis (PS) or regurgitation (PR). We described our experience with PPVI, specifically valve-in-valve transcatheter replacement using the Melody and novel self-expandable systems Pulsta valve. reviewed data from 42 patients undergoing PPVI. Twenty-nine had valves in mostly bioprosthetic valves, valved conduits, homografts position. Following implantation, peak right ventricle-to-pulmonary artery gradient decreased 51.3 ±...