- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Disaster Response and Management
- Emergency and Acute Care Studies
- Transplantation: Methods and Outcomes
- Antifungal resistance and susceptibility
- Congenital Diaphragmatic Hernia Studies
- Pharmaceutical studies and practices
- Family and Patient Care in Intensive Care Units
- Neurogenetic and Muscular Disorders Research
- Anesthesia and Sedative Agents
- Childhood Cancer Survivors' Quality of Life
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical Practices and Patient Outcomes
- Pneumocystis jirovecii pneumonia detection and treatment
- Patient Safety and Medication Errors
- Trauma and Emergency Care Studies
- Neutropenia and Cancer Infections
- Lymphatic Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Celiac Disease Research and Management
- Pediatric Hepatobiliary Diseases and Treatments
Seoul Medical Center
2023-2024
Yonsei University
2023
Hanyang University Medical Center
2022
Seoul National University Children's Hospital
2022
Seoul National University
2013-2021
Seoul National University Hospital
2014-2021
Hanyang University Seoul Hospital
2021
Anyang University
2021
Despite the high prevalence of potential drug-drug interactions in pediatric intensive care units, their clinical relevance and significance are unclear. We assessed characteristics risk factors clinically relevant to facilitate efficient monitoring units. This retrospective cohort study reviewed medical records 159 patients aged <19 years who were hospitalized unit at Seoul National University Hospital (Seoul, Korea) for ≥3 days between August 2019 February 2020. Potential screened using...
Over the last decade, extracorporeal membrane oxygenation (ECMO) use in critically ill children has increased and is associated with favorable outcomes. Our study aims to evaluate current status of pediatric ECMO Korea, a specific focus on its volume changes survival rates based diagnostic indications.
Introduction Children with hereditary neuromuscular diseases (NMDs) are at a high risk of morbidity and mortality related to respiratory failure. The use home mechanical ventilation (HMV) has saved the lives many children NMD but, due lack studies, dependable guidelines not available. We drew upon our experience compare various underlying NMDs evaluate HMV regard morbidity, proper indications timing for its use, develop policy improve quality noninvasive (NIV). Methods retrospectively...
Abstract Background The number of technology-dependent children (TDC) is increasing in South Korea, but available healthcare services after their discharge are poor. This study aimed to examine how TDC and caregivers live at home identify difficulties needs regarding care with few support them. Methods cross-sectional was conducted a tertiary hospital for Korea. A self-reported questionnaire completed by primary who were younger than 19 years had been dependent on medical devices more 3...
The aim of this study was to describe the structure, organization, management, and staffing pediatric critical care (PCC) in Korea.We directed a questionnaire survey for all Upper Grade General Hospitals (n = 43) Korea 2015. first mainly about responses were obtained from 32 hospitals. second patients management. Responses 18 hospitals.Twelve had intensive units (PICUs) 11 them PICU which exclusive children. Total number beds 113. ratio children 1:77,460 is lower than that other developed...
Background: Early recognition of deterioration events is crucial to improve clinical outcomes. For this purpose, we developed a deep-learning-based pediatric early-warning system (pDEWS) and aimed validate its performance. Methods: This retrospective multicenter cohort study including five tertiary-care academic children’s hospitals. All patients younger than 19 years admitted the general ward from January 2019 December were included. Using patient electronic medical records, evaluated...
To evaluate the efficacy and safety of fentanyl for sedation therapy in mechanically ventilated children.This was a double-blind, randomized controlled trial patients between 2 months 18 years age. Patients were randomly divided into two groups; control group with midazolam alone, combination both midazolam. The level evaluated using Comfort Behavior Scale (CBS), infusion rates adjusted according to difference measured target CBS score.Forty-four recruited allocated, 22 groups. time ratio...
Considerable evidence has been published since the 2020 Korean Cardiopulmonary Resuscitation Guidelines were reported. The International Liaison Committee on (ILCOR) also publishes Consensus CPR and Emergency Cardiovascular Care Science with Treatment Recommendations (CoSTR) summary annually. This review provides expert opinions by reviewing recent ILCOR treatment recommendations. authors reviewed CoSTR in 2021 2022. PICO (patient, intervention, comparison, outcome) questions for each topic...
DC is caused by defects at the level of telomere maintenance, and cells from patients with this disease have abnormally short telomeres show premature senescence. One consequence bone marrow failure. Thus, often require HSCT. However, HSCT does not ameliorate other DC-related manifestations. In fact, can accelerate organ dysfunction due to treatment-related complications, solid transplantation required in some DC. report, we describe clinical course a 5-year-old boy who was transferred our...
Acute cerebral infarctions are rare in children, however they can occur as a complication of Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or hypercoagulable state. We report on the case 5-year-old boy who had an extensive stroke multiple cerebrovascular territories 10 days after diagnosis MP infection. Based suspicion that infarction was associated with macrolide-resistant infection, patient treated levofloxacin, methyl-prednisolone, intravenous immunoglobulin,...
PC are a main cause of death following HSCT in children. We aimed to evaluate early predictors mortality paediatric recipients with PCs. A retrospective observational study 35 patients 49 episodes PI on chest radiography (of 124 patients) who had undergone at tertiary university hospital between January 2011 and December 2012 was performed. During follow-up (median 26.1 months), 15 led (30.6%). An aetiologic diagnosis made by non-invasive tests 24 (49.0%) adding bronchoalveolar lavage and/or...
Korean pediatric cardiopulmonary resuscitation (CPR) guideline is the medical recommendation derived on basis of scientific evidence for basic life support (PBLS).This based consensus and treatment recommendations provided by International Liaison Committee Resuscitation in 2020, which provides CPR guideline.Studies published PBLS were additionally considered. 1 The revised items that are high clinical importance require further consideration reviewed an acceptable adaptation or hybrid...
Safety and efficacy are essential in the process of disease treatment. However, off-label medication use is inevitable because various medications do not contain regulatory labels for pediatric use. We aimed to examine analyze risk factors correlated with adverse drug reactions (ADRs). This study was performed retrospectively using electronic medical data from a intensive care unit (PICU) tertiary hospital Korea July 2019 June 2020. A total 6,183 prescribed 502 PICU patients were examined...
Vancomycin is known to be unintentionally eliminated by continuous renal replacement therapy, and the protein bound fraction of vancomycin also different in adults children. However, there are only a few studies investigating relationship between dose venovenous hemodiafiltration (CVVHDF) parameters serum concentration pediatric patients. The aim this study was determine clinical demographic that significantly affect concentrations. This retrospective cohort conducted at intensive care unit...
NICE clinical guideline 50 Developed by the Centre for Clinical Practice at Acutely ill patients in hospital Recognition of and response to acute illness adults hospital: recognition Ordering information You can download following documents from www.nice.org.uk/CG050• The full (this document) -all recommendations, details how they were developed, reviews evidence based on.• A quick reference guide -a summary recommendations healthcare professionals.• 'Understanding guidance' -information...
Korean pediatric cardiopulmonary resuscitation (CPR) guidelines refer to the medical recommendations derived from scientific evidence for advanced life support (PALS).These are based on consensus and treatment made in 2020 by International Liaison Committee Resuscitation, which establishes CPR guideline.Studies published PALS were considered formulating it. 1Evidence revised items that is of high clinical importance requires additional consideration was reviewed an acceptable adaptation or...
Although few adverse effects have been reported for itraconazole, a widely used antifungal therapy febrile neutropenia, we found intravenous (IV) itraconazole to be associated with serious cases of blood pressure (BP) drop. We therefore evaluated the incidence and risk factors BP drop during IV administration drug.We reviewed medical records children hemato-oncologic disease who were treated from January 2012 December 2013. By analyzing systolic (SBP) measurements made 4 hours before through...
Abstract Background Some infants with severe bronchopulmonary dysplasia (sBPD) are referred to higher‐level centers for multidisciplinary care, including the pediatric intensive care unit (PICU). However, information regarding these is limited in PICUs. Methods We investigated characteristics and outcomes of preterm sBPD PICU a tertiary hospital. This retrospective cohort study included 14 who were transferred beyond 40 weeks’ postmenstrual age (PMA) because weaning failure, from January 1,...
Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. We report a case KD with respiratory distress syndrome (ARDS) after intravenous immunoglobulin (IVIG) infusion. Lung manifestations associated have previously been reported in the literature. Although IVIG infusion effective therapy for KD, there are some complications related to infusion: hypotension, aseptic meningitis, renal failure, hemolytic anemia, etc. The here was treated and aspirin. A few days recovery from...
Phacomatosis pigmentovascularis (PPV) is a rare syndrome characterized by concurrent nevus flammeus (capillary malformation) and pigmentary nevus.According to current research, the major pathophysiologic mechanism in PPV venous dysplasia with resultant compensatory collateral channels hypertension.Arterial involvement rare.We herein report our experience on renovascular hypertension, intermittent claudication, severe rhabdomyolysis due diffuse stenosis of multiple arteries patient type IIb...
Disseminated neonatal herpes simplex virus (HSV) infection is one of the most severe infections, and can have devastating consequences without early proper treatment.However, administration acyclovir often be delayed because symptoms signs HSV are non-specific polymerase chain reaction (PCR) results may negative in course infection.We report a case disseminated that was diagnosed by type 1 PCR on day 8 admission.Despite acyclovir, patient cured subsequently discharged after 30 days...
6세 남아가 인플루엔자 A 바이러스 감염 이후 급성 호흡부전 상태에서 내원하였다. 기관 삽관 인공 호흡 및 산화 질소 공급에도 호흡성 산증 저산소증의 호전이 없어 내원 9시간 체외막 산소 공급을 이용하여 보조를 시행하였다. 12시간 기관지경을 우측 중간 기관지부터 상엽 구멍을 막고 있는 단단한 점액 마개를 제거하였다. 환자는 신경계와 호흡기계 후유증 없이 퇴원하였다. 저자들은 플라스틱 기관지염으로 인한 부전 상태의 환자에서 신속한 공급 기관지경술의 처치를 시행함으로써 치료한 사례를 보고한다.
Laryngotracheobronchitis (LTB) is a common disease in the pediatric population, and it rarely caused by fungal infection.Acute respiratory failure LTB mainly occurs immunocompromised patients, early diagnosis closely associated with morbidity mortality.However, an appropriate challenging for pediatricians because symptoms signs of Aspergillus spp.are nonspecific.Here, we report case progressive pseudomembranous child suspicion primary immunodeficiency highlight importance investigation,...