TO INVESTIGATE: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and relationship between status clinical or metabolic features this group.We recruited 38 PCOS using Rotterdam criteria. A total 109 premenopausal control were matched patients based on age body mass index. Serum 25-hydroxy concentrations less than 20 ng/mL classified as frank deficiency. Since may play a significant role disturbances PCOS, correlations parameters analyzed separately...

Objectives To determine the effect of acupuncture in treating hot flushes perimenopausal or postmenopausal women. Methods The study was a randomised single-blind sham-controlled clinical trial. Perimenopausal women with moderate severe were to receive real sham acupuncture. Both groups underwent 4-week run-in period before treatment. group received 11 treatments for 7 weeks, and control on non-acupuncture points during same period. followed 8 weeks after end treatment Changes from baseline...

Insulin resistance is a core feature of polycystic ovary syndrome (PCOS). Recently, genome-wide association studies have reported number single-nucleotide polymorphisms (SNPs) with reproducible associations and susceptibilities to type 2 diabetes. We examined the potential between diabetogenic genes uncovered in PCOS Korean women.Case-control study.Women or without PCOS.DNA samples from 377 patients 386 age-matched controls were genotyped.None 12 SNPs six (KCNJ11, TCF7L2, SLC30A8, HHEX, FTO...

Abstract STUDY QUESTION What is the impact of newly recommended antral follicle count (AFC) cutoff for polycystic ovary (PCO) on diagnostic status syndrome (PCOS)? SUMMARY ANSWER Among patients with phenotypes requiring presence PCO diagnosis, approximately half (48.2%) were excluded from having PCOS based new AFC cutoff, although these women had worse metabolic and hormonal profiles than controls indistinguishable remaining regard to major parameters. WHAT IS KNOWN ALREADY In Rotterdam...

Are the genetic polymorphisms of anti-Müllerian hormone (AMH) and type II receptor (AMHR2) genes associated with idiopathic primary ovarian insufficiency (POI) in a Korean population? The distribution AMH AMHR2 POI population was not significantly different from controls. plays an important role regulating both primordial follicle recruitment cyclic selection antral follicles. -482A>G polymorphism earlier menopause nulliparous women GG genotype had 2.6 years onset compared AA women....

The balance between coagulation and fibrinolysis is an essential part in early pregnancy. Mutations methylenetetrahydrofolate reductase (MTHFR) gene lead to decreased activity of the enzyme hyperhomocysteinemia, which then induces platelet aggregation by promoting endothelial oxidative damage, possibly resulting adverse effect on maintenance We investigated role MTHFR single nucleotide polymorphisms (SNPs), C677T A1298C, Korean patients with recurrent pregnancy loss (RPL). conducted a...

The purpose of the current study was to compare circulating levels visfatin between women with polycystic ovary syndrome (PCOS) and those without PCOS assess correlations various parameters. This case-control recruited 74 patients age- body mass index (BMI)-matched controls. Serum were evaluated using enzyme-linked immunosorbent assay. Women divided into 2 subgroups based on presence clinical or biochemical hyperandrogenism. possible differences in serum hyperandrogenic non-hyperandrogenic...

Beneficial and detrimental effect of surgical adenomyomectomy is still controversial in infertile women with severely diffuse adenomyosis. The primary objective this study was to assess whether a novel method fertility-preserving could improve pregnancy rates. secondary evaluate it dysmenorrhea menorrhagia symptoms patients severe A prospective clinical trial conducted between December 2007 September 2016. Fifty infertility due adenomyosis were enrolled after assessments by experts....

STUDY QUESTIONIs a preponderance of small dense low-density lipoprotein-cholesterol (LDL-C) observed in non-obese women with polycystic ovary syndrome (PCOS)?

ObjectiveTo investigate whether specific genetic polymorphisms in the cyclin-dependent kinase inhibitor 2B antisense RNA (CDKN2B-AS) gene and near wingless-type MMTV integration site family member 4 (WNT4) are associated with endometriosis a Korean population.DesignCase-control association study.SettingUniversity.Patient(s)Surgically or histologically diagnosed cases of (n = 673) controls 500) among population ethnic Koreans.Intervention(s)None.Main Outcome Measure(s)Genotype distribution...

Serum anti-Müllerian hormone (AMH) levels are regarded as an age-specific marker for predicting the ovarian reserve in women of reproductive age. Some studies have shown that luteinizing (LH)/follicle stimulating (FSH) ratio can be used a predictor reserve. The purpose this study was to assess variation LH/FSH with aging and evaluate correlation between serum AMH normo-ovulatory women. We retrospectively analyzed day 3 1,251 patients (age range: 20-50 yr) January 2010 2011. divided into 6...

Estrogens are commonly used in gynecologic area, such as oral contraception, hormone replacement therapy, and vitro fertilization-embryo transfer. Although estrogen is a common cause of acute drug-induced pancreatitis, there has been paucity report Korea. Clinical course estrogen-induced pancreatitis usually mild to moderate, but fetal case can occur. In addition, be latency from the first administration symptom. Therefore, physicians should consider possibility disease when woman taking or...

Hominis placenta pharmacopuncture is widely used for climacteric symptoms. This study examined the efficacy and safety of with PLC (the extract placenta) on hot flashes perimenopausal postmenopausal women.This was a randomized placebo-controlled single-blind trial, which recruited 128 women, randomly assigned to receive or normal saline (NS) eight weeks. The primary outcome mean changes in flash score (HFS) secondary outcomes were Menopause Rating Scale (MRS), follicle-stimulating hormone...

To investigate changes in glycaemic status women with polycystic ovary syndrome (PCOS).Longitudinal observational study.Women PCOS who underwent baseline and follow-up screening tests for diabetes (n = 262). Four patients type 2 (T2DM) at 6 were taking drugs the final excluded.Changes classification based on fasting glucose, haemoglobin A1c oral glucose tolerance test.The median length of was 2.9 years. The mean age body mass index normoglycaemia group 202) 23.0 years 21.6 kg/m2 , while it...

BACKGROUNDInsulin resistance is a core feature of polycystic ovary syndrome (PCOS). Phosphatidylinositol (PI) 3-kinase an important enzyme in the early insulin signaling cascade and plays key role insulin-mediated glucose transport. In its regulatory subunit, p85α, there common amino acid substitution (the Met326Ile polymorphism), this may be crucial for function p85α subunit PI3-kinase.

This study was conducted to demonstrate the effectiveness and safety of herbal medicine acupuncture treatment in unexplained infertile females.One hundred patients were recruited from 3 Korean Medicine hospitals Korea they voluntarily signed informed consent agreements. Participants took Onkyeong-tang (120cc) twice daily between menstrual cycle day (MCD) 12, for ovulation implantation MCD 13 28. They also received moxibustion during 4 cycles. After period, there observation periods. The...