Little information is available regarding the demographic characteristics and outcomes of patients with prosthetic joint infection (PJI) resulting from gram-negative (GN) organisms, compared PJI gram-positive (GP) organisms.We performed a retrospective cohort analysis all cases that were treated at our institution during period 2000 through 2006.GN microorganisms involved in 53 (15%) 346 first-time episodes PJI, Pseudomonas aeruginosa was most commonly isolated pathogen (21 [40%] episodes)....

Background: A two-stage revision is a well-accepted method for the treatment of deep infection hip with joint implant. In present study, results associated interim use antibiotic-loaded cement beads were compared those an prosthesis. Methods: One hundred and twenty-eight consecutive patients who managed arthroplasty followed clinically radiographically average 4.9 years. Cement implanted following resection in first seventy hips, custom prosthesis was subsequent fifty-eight hips. Results:...

<h3>Background and Objectives</h3> The effectiveness of acupuncture in relieving acute postoperative pain is still controversial. This patient-evaluator blinded sham auricular (AA)–controlled study tested whether effective controlling after total knee arthroplasty. <h3>Methods</h3> Patients were randomly assigned to receive true (knee, scalp, AA) or AA. All procedures conducted under general anesthesia, the AA needles retained situ for 3 days. Postoperative was managed with intravenous...

This study investigated the release of antibiotics in vivo, from an articulating polymethylmethacrylate (PMMA) spacer used two-stage revision arthroplasty infected hip implants. Forty-six patients who underwent for infections were managed with interim PMMA loaded a high dose vancomycin and aztreonam. Serum aliquots drainage collected after first-stage surgery, joint fluid obtained at time second-stage surgery analyzed antibiotic concentrations by performance liquid chromatography bioactivity...

Background Fungal infection at an arthroplasty site is rare and poses a therapeutic challenge. To the best of our knowledge, no reports have been published thus far on success rate prosthesis reimplantation after fungal prosthetic joint infections. Questions/purposes We asked: (1) What in terms eradication using two-stage exchange patients with hip or knee periprosthetic infections, particularly focusing Candida infections? (2) patient-, infection-, treatment-related variables are associated...

Background Mobile phones (MPs) have been an essential part of the lives healthcare professionals and improved communication, collaboration, sharing information. Nonetheless, widespread use MPs in hospitals has raised concerns nosocomial infections, especially areas requiring highest hygienic standards such as operating rooms (ORs). This study evaluated incidence bacterial contamination carried by medical staff working OR determined its association with colonization this personnel. Methods is...

The study aims to analyze the demographics and microbiological profiles of hip knee prosthetic joint infection (PJI) compare differences between PJI.We performed a retrospective all PJI cases January 2006 December 2014 at referral medical center in Taiwan.A total 294 were collected: 159 identified as 135 PJI. most common causative pathogen was Staphylococcus aureus (78 cases, 27%), followed by coagulase-negative staphylococci (CoNS, 42 14%). Methicillin-resistant (MRS) accounted for 21%...

Antibiotic-loaded bone cement (ALBC) is widely used in orthopaedic surgery for both prevention and treatment of infection. Little known about the effect different brand combinations antibiotic on elution profile mechanical strength ALBC. Standardized specimens that consisted one 4 brands 3 vancomycin were fashioned, producing 12 Two dosages 40g to represent high (4g vancomycin) low (1g dose groups. Concentrations from ALBC was measured up 336 hours. The ultimate compression tested at axial...

The aim of this study was to determine the optimal formulation antibiotic-loaded bone cement for knee periprosthetic joint infection. We used both in vitro and vivo models incorporating various broad-spectrum antibiotics tested their efficacy against gram-positive gram-negative bacteria.Bone specimens loaded with 4 g either vancomycin or teicoplanin ceftazidime, imipenem, aztreonam were studied measure antibiotic release characteristics antibacterial capacities methicillin-susceptible...

Two-stage reconstruction is a well-recognized treatment for deep infection of hip joint implants. The purpose the study was to report results our using standardized protocol.Forty-two consecutive patients with prosthesis were treated according prospective, two-stage resection/reimplantation protocol. Between stages, custom-made, antibiotic-loaded, cement implanted as an interim spacer.Infection eradicated in 41 after first-stage operation. Thirty-six remained ability walk pros-thesis. For 40...

We have carried out in 24 patients, a two-stage revision arthroplasty of the hip for infection with massive bone loss. used custom-made, antibiotic-loaded cement prosthesis as an interim spacer. Fifteen patients had acetabular deficiencies, eight segmental femoral loss and one combined defect. There was no recurrence at mean follow-up 4.2 years (2 to 7). A total 21 remained mobile period. The Merle D'Aubigné Postel score improved from 7.3 points before operation 13.2 between stages 15.8...

The objective of this study was to evaluate the antibacterial effects polymethylmethacrylate (PMMA) bone cements loaded with daptomycin, vancomycin, and teicoplanin against methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant (MRSA), vancomycin-intermediate (VISA) strains. Standardized cement specimens made from 40 g PMMA 1 (low-dose), 4 (middle-dose) or 8 (high-dose) antibiotics were tested for elution characteristics activities. patterns release evaluated using in...

The objective of this study was to compare the elution characteristics, antimicrobial activity and mechanical properties antibiotic-loaded bone cement (ALBC) loaded with powdered antibiotic, antibiotic inert filler (xylitol), or liquid particularly focusing on vancomycin amphotericin B.Cement specimens 2 g B powder (powder group), xylitol (xylitol group) 12 ml solution containing (liquid were tested.Vancomycin enhanced by 234% in group 12% compared group. Amphotericin 265% 65% Based...

Background . Two-stage revision hip arthroplasty is the gold standard for treatment of patients with chronic periprosthetic joint infection (PJI), but few studies have reported outcomes beyond short-term follow-up. Methods A total 155 who underwent two-stage PJI in 157 hips were retrospectively enrolled this study between January 2001 and December 2010. The mean patient age was 57.5 years, prosthetic 3.6 interim interval 17.8 weeks. These followed up an average 9.7 years. Results At latest...

The standard treatment for periprosthetic joint infections (PJI) typically involves a two-stage resection arthroplasty using antibiotic-loaded bone cement (ALBC) spacers. This study hypothesizes that there is no significant correlation between antibiotic levels in blood and synovial fluid the patient's kidney function, success rates of staged are comparable groups, specifically targeting gram-positive bacterial infections. retrospective review included patients treated from 2017 to 2022 with...

Background: Powdered antibiotics are widely used in acrylic bone cement. Liquid antibiotics, however, have rarely been employed. This study investigated the application of liquid gentamicin, a much less costly antibiotic with broad antimicrobial spectrum, cement to treat musculoskeletal infections. Methods: Forty-two patients undergoing two-stage revision hip arthroplasty for periprosthetic infection were managed an interim spacer loaded gentamicin (480 mg per 20 mL pack monomer) or without...

Background Mycobacterium tuberculosis periprosthetic joint infection (TBPJI) is a rare complication of hip/knee arthroplasty. The outcomes TBPJI treatment are still unreported. objective this study was to investigate the following with two-stage exchange Materials and methods From 2003 2013, 11 patients (six hips five knees) were treated arthroplasty at our institution. We collected analyzed variables including demographic data, comorbidities, microbiological duration symptoms, types...