- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Hepatitis Viruses Studies and Epidemiology
- Semiconductor materials and devices
- Health Systems, Economic Evaluations, Quality of Life
- Nanoplatforms for cancer theranostics
- COVID-19 Clinical Research Studies
- Pharmaceutical Practices and Patient Outcomes
- Silicon Nanostructures and Photoluminescence
- Viral Infections and Immunology Research
- Acute Ischemic Stroke Management
- Hepatitis B Virus Studies
- Bacteriophages and microbial interactions
- Wnt/β-catenin signaling in development and cancer
- RNA Interference and Gene Delivery
- Long-Term Effects of COVID-19
- Monoclonal and Polyclonal Antibodies Research
- Hepatitis C virus research
- Viral gastroenteritis research and epidemiology
- Infectious Diseases and Tuberculosis
- Muscle and Compartmental Disorders
- TGF-β signaling in diseases
- Curcumin's Biomedical Applications
- Supramolecular Self-Assembly in Materials
Chung Shan Medical University Hospital
2007-2024
Chung Shan Medical University
2007-2024
Linkou Chang Gung Memorial Hospital
2022-2024
Chang Gung Memorial Hospital
2013-2023
Chang Gung University
2015-2022
University of California, Davis
2021-2022
National Cheng Kung University
2022
National Tsing Hua University
2018-2020
National Taiwan University of Science and Technology
2018
Institute of Plant and Microbial Biology, Academia Sinica
2015
Electroluminescence (EL) of the metal-insulator-semiconductor light-emitting diodes (MISLEDs) made by Si-rich SiNx and SiOx films with buried Si nanocrystals are compared. The facilitates carrier transport EL from MISLED turn-on current voltage 4 μA 12 V reducing barrier heights at indium tin oxide /SiNx SiNx/Si-nc interfaces. exhibits larger charge loss rate 12% within 200 s shorter delay time 3.86×10−4 sec than one, which limit its external quantum efficiency strong escaping effect due to...
Colorectal cancer (CRC) is a serious public health problem that results due to changes of diet and various environmental stress factors in the world. Curcumin traditional medicine used for treatment wide variety tumors. However, antimetastasis mechanism curcumin on CRC has not yet been completely investigated. Here, we explored underlying molecular mechanisms metastasis cells vitro vivo . significantly inhibits cell migration, invasion, colony formation reduces tumor growth liver We found...
Background . Two-stage revision hip arthroplasty is the gold standard for treatment of patients with chronic periprosthetic joint infection (PJI), but few studies have reported outcomes beyond short-term follow-up. Methods A total 155 who underwent two-stage PJI in 157 hips were retrospectively enrolled this study between January 2001 and December 2010. The mean patient age was 57.5 years, prosthetic 3.6 interim interval 17.8 weeks. These followed up an average 9.7 years. Results At latest...
The nonstoichiometric ITO/n-SiC/i-SiC/p-Si/Al light-emitting diodes (LEDs) with dense Si quantum dots (Si-QDs) embedded in the Si-rich <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> C xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> -based i-SiC layer are demonstrated. films buried Si-QDs grown by plasma-enhanced chemical vapor deposition varying substrate temperatures. After annealing process, average Si-QD size...
Treatment with exogenous nitric oxide (NO) donors is regarded as being effective against osteoporosis. However, NO has a short half-life, limiting its clinical usefulness. To overcome this limitation, an injectable microparticle (MP) system developed that consists of phase-change materials capric acid (CA) and octadecane, encapsulates donor. The therapeutic efficacy the MPs evaluated in ovariectomized (OVX) rats Upon subcutaneous administration, undergo phase transition, leaching out donor...
BACKGROUND The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool detecting necrotizing fasciitis (NF). Its application, however, is mainly NF types I and II. practical relevance of the LRINEC Vibro vulnificus–related skin soft tissue infection (SSTI) was hardly ever investigated. aim this study to assess applicability scoring system identify NF-predicting factors in patients with V. vulnificus–caused SSTI. METHODS A retrospective...
Protocadherin 10 ( PCDH10 ), a novel tumor suppressor gene in human cancers, is located common deleted region at chromosome 4q28 colorectal cancer (CRC). This study aimed to ascertain the genetic loss of and its clinical relevance CRC explore function PCDH10. The deletion was determined 171 pairs primary tumors corresponding normal mucosae by heterozygosity study. In total, 53 carcinomas were positive for allelic . aberration significantly associated with progression distant metastasis p =...
Abstract Nitric oxide (NO) is a potent tumor‐cell radiosensitizer but it can be readily scavenged by hemoglobin (Hb) in vivo. A biomimetic incubator that generate and deliver NO scavenger (Hb)‐free environment to enhance its radiosensitizing effect maximize efficacy radiotherapy proposed. This comprises poly(lactic‐co‐glycolic acid) (PLGA) hollow microsphere (HM) contains an donor (NONOate) surfactant molecule (sodium caprate, SC) aqueous core. In acidic tumorous environments, the PLGA shell...
Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one treatment-refractory malignancies. The current treatment options for patients with metastatic are limited in cases non-curative. This review focuses on conventional chemotherapeutic drugs treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables traditional herbal medicines as...
Journal Article Corrected proof Impact of prehospital care and door-to-computed tomography scan time on stroke outcomes Get access Kai-Lun Sheu, Sheu Conceptualization, Investigation, Methodology, Validation, Writing - original draft, review & editing Institute Medicine, Chung Shan Medical University, Taichung, TaiwanSchool TaiwanDepartment Family Community University Hospital, Taiwan Search for other works by this author on: Oxford Academic PubMed Google Scholar Shiuan-Chih Chen, Chen...
Background The public vaccination program of hepatitis B virus (HBV) was launched during 1984 in Taiwan, China. However, the long-lasting protective efficacy HBV among adolescents older than 15 years age seldom recorded. Methods A seroepidemiological survey conducted 4575 first-year university students China 2000 to 2003, including serological data by testing surface antigen (HBsAg), antibody (anti-HBs), core (anti-HBc) and demographic information. Results HBsAg carrier rate male born before...
Targeted delivery of diagnostics and therapeutics offers essential advantages over nontargeted systemic delivery. These include the reduction toxicity, ability to reach sites beyond biological barriers, higher cargo concentrations diseased sites. Virus-like particles (VLPs) can efficiently be used for targeted purposes. VLPs are derived from coat proteins viral capsids. They self-assembled, biodegradable, homogeneously distributed. In this study, hepatitis E virus (HEV) VLP derivatives,...
Radio-frequency identification (RFID) technologies allow remote as well generic data access using radio waves. It is also commonly used in transportation and other payment systems, e.g., the MIFAREof NXP Semiconductors, one of most widely deployed contactless smart card standards. Recently, interest RFID for micro grows rapidly users get to convenience brought by RFID,and corporations discover that can significantly lower cost operation. However, there are security concerns, many passive do...
Austin-Moore hemiarthroplasty (HA) had been selectively used for elderly patients with femoral neck fractures. With increasing life span and activity, the sequela of HA make implant no longer favorable. The treatment failed advanced acetabular erosion is challenging; however, little has published regarding this topic. aim study was to evaluate mid-term results using cementless total hip arthroplasty (THA) in octogenarians. Between 2008 2011, 47 (32 women 15 men) an average age 86 years...
The advantages of unicompartmental knee arthroplasty (UKA) have led to the procedure being increasingly performed worldwide. However, revision surgery is required after UKA failure. According literature review, choice implant in remains a debatable concern. This study analyzed clinical results different types prostheses used treating failed UKA.This retrospective review 33 medial UKAs between 2006 and 2017. Demographic data, failure reason, prostheses, severity bone defects were analyzed....