A5034809509- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Memory and Neural Mechanisms
- Cardiac Arrest and Resuscitation
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Anesthesia and Neurotoxicity Research
- Pesticide Exposure and Toxicity
- Nanoparticles: synthesis and applications
- Pelvic and Acetabular Injuries
- Disaster Response and Management
- Neurological Disorders and Treatments
- Advanced Nanomaterials in Catalysis
- Fetal and Pediatric Neurological Disorders
- Hip and Femur Fractures
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Advanced MRI Techniques and Applications
Clinical Research Institute
2020-2024
Carle Foundation Hospital
2020-2024
Imaging Center
2024
Illinois College
2024
Center for Neuroscience and Regenerative Medicine
2019-2021
National Institutes of Health
2020
Uniformed Services University of the Health Sciences
2020
University of Illinois Urbana-Champaign
2016
Quinnipiac University
2008
Virginia Commonwealth University
2004-2006
Objective The primary objective of this study was to track the incidence and progression traumatic microbleeds (TMBs) for up five years following brain injury (TBI).Methods Thirty patients with mild, moderate, or severe TBI received initial MRI within 48 h continued in a longitudinal years. findings assessed across year period. In addition TMBs, we noted presence other imaging including diffusion weighted (DWI) lesions, extra-axial intraventricular hemorrhage, hematoma, meningeal enhancement...
Study Design: This was a survey of the surgeon members Lumbar Spine Research Society (LSRS). Objective: The purpose this study to assess trends in surgical practice and patient management involving elective emergency surgery early months coronavirus pandemic. Summary Background Data: novel has radically disrupted medical care first half 2020. Little data exists regarding exact nature its effect on spine care. Methods: A 53-question sent LSRS. Respondents were contacted via email 3 times over...
Abstract Traumatic brain injury impairs function of the glymphatic system, a perivascular network involved in waste clearance. Enlarged spaces visible on MRI are an emerging biomarker function. This study characterized enlarged acute head with 7 T MRI. Healthy controls (n = 8) and patients 11) mild traumatic underwent within days were evaluated for lifetime history injury, neurobehavioral symptoms sleep disturbances. MRI-visible quantified assessed according to published criteria. The number...
Chronic cognitive impairment is an enduring aspect of traumatic brain injury (TBI) in both humans and animals. Treating the post-traumatic stages often involves delivery pharmacologic agents aimed at specific neurotransmitter systems. The current investigation examined effects nootropoic drug aniracetam on recovery following TBI rats. Three experiments were performed to determine (1) optimal dose for treating impairment, (2) effect delaying treatment a period days TBI, (3) terminating before...
Memory impairment following traumatic brain injury (TBI) is common in both humans and animals. A noteworthy feature of memory dysfunction human TBI impaired performance that dependent on the delay between initial learning recall information. However, previous studies TBI-induced animals have failed to control for amount sham injured The present study demonstrates experimental rats produces delay-dependent impairment, even when degree controlled for. Animals were at a moderate level lateral...
Magnetic resonance imaging (MRI) is used rarely in the acute evaluation of traumatic brain injury (TBI) but may identify findings clinical importance not detected by computed tomography (CT). We aimed to characterize association cytotoxic edema and hemorrhage, including microbleeds, on MRI obtained within hours head trauma investigated relationship outcomes. Patients prospectively enrolled Traumatic Head Injury Neuroimaging Classification study (NCT01132937) with evidence diffusion-related...
Severe traumatic brain injury (TBI) is a leading cause of death and disability worldwide, especially in low- middle-income countries, austere, rural, remote settings. The purpose this Perspective to challenge the notion that accurate actionable diagnosis most severe injuries should be limited physicians other highly-trained specialists located at hospitals. Further, we aim demonstrate great opportunity improve TBI care prehospital setting. Here, discuss potential applications diagnostics,...