A5102778875- Venous Thromboembolism Diagnosis and Management
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Diabetes Treatment and Management
- Airway Management and Intubation Techniques
- Pneumonia and Respiratory Infections
- Long-Term Effects of COVID-19
- Ultrasound in Clinical Applications
- Sepsis Diagnosis and Treatment
- Tracheal and airway disorders
- Acute Ischemic Stroke Management
- COVID-19 and healthcare impacts
- Intensive Care Unit Cognitive Disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Phenothiazines and Benzothiazines Synthesis and Activities
- Antiplatelet Therapy and Cardiovascular Diseases
- Porphyrin Metabolism and Disorders
- Hereditary Neurological Disorders
- Complement system in diseases
- Lysosomal Storage Disorders Research
- Advanced X-ray and CT Imaging
- Diabetes Management and Education
- Pancreatic function and diabetes
NYU Langone Health
2018-2024
LMC Diabetes & Endocrinology (Canada)
2015-2024
New York University
2010-2023
Alberta Hospital Edmonton
2023
Pulmonary and Critical Care Associates
2020
Ajuntament de L’Hospitalet
2020
Italian Society of Physiotherapy
2020
University Health Network
2017
Brigham and Women's Hospital
2017
Harvard University
2017
To determine the prevalence of D-dimer elevation in coronavirus disease 2019 (COVID-19) hospitalization, trajectory levels during and its association with clinical outcomes. Approach Results: Consecutive adults admitted to a large New York City hospital system positive polymerase chain reaction test for SARS-CoV-2 (severe acute respiratory syndrome 2) between March 1, 2020 April 8, were identified. Elevated was defined by laboratory-specific upper limit normal (>230 ng/mL). Outcomes included...
BackgroundCoronavirus 2019 (COVID-19) is a worldwide pandemic, with many patients requiring prolonged mechanical ventilation. Tracheostomy not recommended by current guidelines as it considered superspreading event owing to aerosolization that unduly risks health care workers.MethodsPatients severe COVID-19 who were on ventilation for 5 days or longer evaluated percutaneous dilational tracheostomy. We developed novel tracheostomy technique placed the bronchoscope alongside endotracheal tube,...
The left ventricular outflow tract (LVOT) velocity time integral (VTI) is an easily measured echocardiographic stroke volume index analog. Low values predict adverse outcomes in failure. We postulate the VTI may be a signal of right dysfunction acute pulmonary embolism, and therefore predictor poor outcomes. retrospectively reviewed echocardiograms on all Pulmonary Embolism Response Team activations at our institution embolism diagnosis. LVOT was defined as ⩽ 15 cm. examined two composite...
To assess the impact of percutaneous dilational tracheostomy in coronavirus disease 2019 patients requiring mechanical ventilation and risk for healthcare providers.Prospective cohort study; were enrolled between March 11, April 29, 2020. The date final follow-up was July 30, We used a propensity score matching approach to compare outcomes. Study outcomes formulated before data collection analysis.Critical care units at two large metropolitan hospitals New York City.Five-hundred forty-one...
Coronavirus disease 2019 (COVID-19) is associated with increased rates of deep vein thrombosis (DVT) and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been improved outcomes. We aimed to investigate whether PERT utilization, recommendations, outcomes for patients diagnosed acute PE changed during the COVID-19 pandemic. This a retrospective cohort study all adult who received care at an academic hospital system in New York City between March 1st April 30th,...
In the present study, we sought to better characterize patients with coronavirus disease 2019 (COVID-19) most at risk of severe, outpatient thrombosis by defining hospitalized COVID-19 arterial or venous diagnosed admission.We conducted a single-center, retrospective analysis patients. We found shift in proportions subtypes from 2020, declines ST-segment myocardial infarction (from 22.0% 10.1% thrombotic events) and stroke 48.6% 37.2%) an increase thromboembolism 29.4% 52.7%). The...
Corticosteroids and tocilizumab have been shown to improve survival in patients who require supplemental oxygen from coronavirus disease 2019 (COVID-19) pneumonia. The optimal dose of immunosuppression for the treatment COVID-19 acute respiratory distress syndrome (ARDS) is still unknown.The objective this study was evaluate effectiveness safety high- versus low-dose corticosteroids with or without ARDS.This a retrospective admitted intensive care unit (ICU) requiring mechanical ventilation...
Hemoadsorption with CytoSorb has been used as an adjunct in the treatment of severe coronavirus disease 2019 (COVID-19)-related respiratory failure. It remains unknown if hemoadsorption will alter sedative and analgesic dosing critically ill patients on venovenous extracorporeal membrane oxygenation (VV-ECMO). We conducted a retrospective review COVID-19 requiring VV-ECMO for support. Patients who were enrolled clinical study compared alone. Data collected 72-hour therapy additional 72 hours...
Background: Parameters within reconstitution, storage, stability, and administration may be optimized according to the unique pharmacokinetics of each antibiotic ensure a successful desensitization. Objective: The study aims evaluate successfulness safety desensitization protocols developed by pharmacy department at our institution. Methods: A retrospective was conducted an 800-bed, urban, tertiary care, academic medical center. total 36 patients 18 years age or older, admitted intensive...
BMycoplasma pneumoniae (M. pneumoniae) infection is rarely fatal in young adults. Most patients have no symptoms or mild nonspecific signs with infection. Up to 310% infected people may develop pneumonia. We herein report a case of M. presenting acute respiratory failure and brain death 27 year old female. Autopsy revealed that diffuse alveolar damage the lungs hemorrhagic leukoencephalopathy (AHLE), hyperacute form disseminated encephalomyelitis (ADEM) brain. [N A J Med Sci. 2012;5(2):126-130.]
This is a report of 41-year-old professional male bodybuilder with history active anabolic-androgenic steroid abuse and normal echocardiogram two years prior to admission who experienced near-fatal arrhythmia during anaesthetic induction for elective orthopaedic surgery. The patient had severe concentric left ventricular hypertrophy, diffuse hypokinesis, decreased ejection fraction inducible monomorphic tachycardia. A single-chamber cardioverter/defibrillator was inserted.
Introduction: Reperfusion injury after cardiac arrest (CA) leads to poor survival and neurological outcomes. We hypothesized that a combination of pharmacologic neuroprotection therapies administered 24-72 hours post-CA [“combination therapy”] target key steps in reperfusion injury; 1) excitotoxicity (Magnesium, Memantine, Perampanel, Minocycline), 2) mitochondrial dysfunction (Thiamine, Coenzyme Q10), 3) oxidative stress (Vitamin C, Vitamin E), 4) inflammation (Hydrocortisone), would...
ObjectivesProning patients with acute respiratory distress syndrome (ARDS) has been associated increased survival, although few data exist evaluating the safety and feasibility of proning ARDS on extracorporeal membrane oxygenation (ECMO).MethodsA single-institution retrospective review all placed ECMO between March 1 May 31, 2020, was performed. All events were evaluated for complications, as well change in compliance, sweep, oxygenation, flow. The primary outcome this study rate major...
A morbidly obese middle aged woman in her 40's presented to another hospital with methicillin resistant staphylococcus aureus pneumonia and subsequently developed severe acute respiratory distress syndrome. Her oxygenation demonstrated no improvement low tidal volume ventilation, paralysis, or prostagladin therapy. She was unable be manually proned secondary habitus. transferred our facility, where she initiated on VV-ECMO. Maximal flow through the ECMO circuit inadequate for given...
A 49-year-old woman presented to the hospital with shortness of breath 2 weeks after a left total hip replacement. She was found have submassive pulmonary embolism (PE), her case complicated by detection large mobile clot in transit extending through patent foramen ovale between right and atria. The presence this free-floating heart thrombus (FFRHT) increases risks stroke mortality, yet optimal approach treatment unclear. Ultimately, intravenous tissue plasminogen activator administered...