A5060463866- Transplantation: Methods and Outcomes
- Tracheal and airway disorders
- Organ Transplantation Techniques and Outcomes
- Respiratory viral infections research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Renal Transplantation Outcomes and Treatments
- Polyomavirus and related diseases
- Airway Management and Intubation Techniques
- Mechanical Circulatory Support Devices
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Organ Donation and Transplantation
- Hepatitis C virus research
- Gut microbiota and health
- Venous Thromboembolism Diagnosis and Management
- Esophageal and GI Pathology
- COVID-19 Clinical Research Studies
- Medical Imaging and Pathology Studies
- Ultrasound in Clinical Applications
- Pleural and Pulmonary Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Central Venous Catheters and Hemodialysis
- Viral-associated cancers and disorders
Miami Transplant Institute
2019-2024
NYU Langone Health
2018-2024
New York University
2020-2024
Pulmonary and Critical Care Associates
2014-2024
SleepMed
2024
Universidad La Salle
2021
The University of Texas Health Science Center at San Antonio
2008-2020
FC Barcelona
2020
Universidad de La Sabana
2018
The University of Texas at San Antonio
2016
This document was developed through the collaborative efforts of Society Critical Care Medicine, American College Chest Physicians, and Association Organ Procurement Organizations. Under auspices these societies, a multidisciplinary, multi-institutional task force convened, incorporating expertise in critical care medicine, organ donor management, transplantation. Members were divided into 13 subcommittees, each focused on one following general or organ-specific areas: death determination...
<h3>Importance</h3> Preliminary clinical trials have demonstrated that endobronchial coils compress emphysematous lung tissue and may improve function, exercise tolerance, symptoms in patients with emphysema severe hyperinflation. <h3>Objective</h3> To determine the effectiveness safety of coil treatment. <h3>Design, Setting, Participants</h3> Randomized trial conducted among 315 air trapping recruited from 21 North American 5 European sites December 2012 through November 2015....
BackgroundCoronavirus 2019 (COVID-19) is a worldwide pandemic, with many patients requiring prolonged mechanical ventilation. Tracheostomy not recommended by current guidelines as it considered superspreading event owing to aerosolization that unduly risks health care workers.MethodsPatients severe COVID-19 who were on ventilation for 5 days or longer evaluated percutaneous dilational tracheostomy. We developed novel tracheostomy technique placed the bronchoscope alongside endotracheal tube,...
Respiratory failure is associated with increased mortality in COVID-19 patients. There are no validated lower airway biomarkers to predict clinical outcome. We investigated whether bacterial respiratory infections were poor outcome of a prospective, observational cohort 589 critically ill adults, all whom required mechanical ventilation. For subset 142 patients who underwent bronchoscopy, we quantified SARS-CoV-2 viral load, analysed the tract microbiome using metagenomics and...
Rationale: One of the limitations associated with lung transplantation is lack available organs.Objective: To determine whether a donor–management protocol could increase number lungs for without affecting survival rates recipients.Methods: We implemented San Antonio Lung Transplant managing potential donors according to modifications standard criteria donor selection and strategies management. then compared information gathered during 4-yr period, which was used period before...
Decision-making in the timing of tracheostomy patients with coronavirus disease 2019 (COVID-19) has centered on intersection long-standing debates benefits early vs late tracheostomy, assumptions about timelines infectivity novel coronavirus, and concern over risk to surgeons performing tracheostomy. Multiple consensus guidelines recommend avoiding or delaying without evidence indicate anticipated improvement outcomes as a result.To assess from airway management COVID-19 requiring mechanical...
The role of tracheostomy during the coronavirus disease 2019 (COVID-19) pandemic remains unknown. goal this consensus statement is to examine current evidence for performing in patients with respiratory failure from COVID-19 and offer guidance physicians on preparation, timing, technique while minimizing risk infection health care workers (HCWs).A panel including intensivists interventional pulmonologists three professional societies representing 13 institutions experience managing across a...
Invasive fungal infections (IFI) are common after lung transplantation and there limited data for the use of antifungal prophylaxis in these patients. Our aim was to compare safety describe effectiveness universal with two azole regimens transplant recipients. This is a retrospective study recipients from July 2003 2006 who received itraconazole or voriconazole plus inhaled amphotericin B incidence hepatotoxicity. Secondary outcomes include describing IFI, clinical IFI mortality. Sixty-seven...
Pulmonary lymphangioleiomyomatosis (LAM) is a slow-progressing metastatic disease that driven by mutations in the tumor suppressor tuberous sclerosis complex 1/2 (TSC1/2). Rapamycin inhibits LAM cell proliferation and only approved treatment, but it cannot cause regression of existing lesions can stabilize disease. However, other cancers, immunotherapies such as checkpoint blockade against PD-1 its ligand PD-L1 have shown promise causing even curing some patients. Thus, we asked whether has...
Background As early as the 1920's, researchers noted a relationship between caloric restriction, weight loss and decreased incidence of hypertension (Terry 1922, Preble 1923, Bauman 1928, Master 1929). In 1988 meta‐analysis aggregate data from 12 prospective studies, including 5 randomized controlled trials (RCTs), found that on average each 1 kilogram decrease in body obese hypertensive patients was associated with 2.4 mm Hg systolic 1.5 diastolic blood pressure (Staessen 1988). Blood...
Acute cellular rejection (ACR) after lung transplant is a leading risk factor for chronic allograft dysfunction. Prior studies have demonstrated dynamic microbial changes occurring within the and gut that influence local adaptive innate immune responses. However, microbiome's overall impact on ACR remains poorly understood.
To assess the impact of percutaneous dilational tracheostomy in coronavirus disease 2019 patients requiring mechanical ventilation and risk for healthcare providers.Prospective cohort study; were enrolled between March 11, April 29, 2020. The date final follow-up was July 30, We used a propensity score matching approach to compare outcomes. Study outcomes formulated before data collection analysis.Critical care units at two large metropolitan hospitals New York City.Five-hundred forty-one...
Previous tracheostomy has been considered a relative contraindication for percutaneous dilational tracheostomy. The objective of this study was to assess the safety in critically ill patients with history previous tracheostomy.Retrospective, single-center case series all consecutive requiring repeat continued mechanical ventilatory support.Intensive care unit tertiary-care referral center.Fourteen (eight female, six male) median age 70 yrs (range, 33-94). All had previously undergone...
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may develop end-stage lung disease requiring transplantation. We report the clinical course, pulmonary pathology radiographic correlation, and outcomes after transplantation in three patients who developed chronic failure due to postacute sequelae of SARS-CoV-2 infection.