A5005698700- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Respiratory viral infections research
- Renal Transplantation Outcomes and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Tracheal and airway disorders
- Genetic and Kidney Cyst Diseases
- Renal and Vascular Pathologies
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Polyomavirus and related diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Organ Transplantation Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- Mycobacterium research and diagnosis
- Anesthesia and Pain Management
- Renal and related cancers
- Pediatric health and respiratory diseases
- Hepatitis C virus research
- Organ and Tissue Transplantation Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Autoimmune and Inflammatory Disorders Research
- SARS-CoV-2 and COVID-19 Research
- Electrospun Nanofibers in Biomedical Applications
NYU Langone Health
2015-2024
New York University
2020-2024
Miami Transplant Institute
2020-2024
Pulmonary and Critical Care Associates
2024
SleepMed
2024
Columbia University Irving Medical Center
2017-2022
New York Hospital Queens
2019
NewYork–Presbyterian Hospital
2019
Columbia University
2019
Tufts Medical Center
2010-2011
Summary Background and objectives Most deaths in autosomal dominant polycystic kidney disease (ADPKD) are attributable to cardiovascular (CVD). We examined novel CVD biomarkers different stages of ADPKD. Design, setting, participants, & measurements recruited 50 hypertensive subjects with ADPKD estimated GFR (eGFR) >60 ml/min per 1.73 m 2 ; 52 eGFR 25 60 42 normotensive healthy controls. assayed serum C-reactive protein IL-6 as markers inflammation; plasma 8- epi -prostaglandin F 2α...
Morphogenesis of epithelial cells involves processes by which kidney shape and function are regulated. The lack in vitro models that sustainable for longer time periods emulating complex intercellular interactions the have limited understanding about tissue morphogenesis its aberrations diseases such as autosomal dominant polycystic disease (ADPKD). A three-dimensional (3D) coculture system normal diseased tissues is reported here. Tubule- ADPKD cyst-derived were cultured extracellular...
Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support, despite growing implementation of ECMO ARDS in the general population.
Acute cellular rejection (ACR) after lung transplant is a leading risk factor for chronic allograft dysfunction. Prior studies have demonstrated dynamic microbial changes occurring within the and gut that influence local adaptive innate immune responses. However, microbiome's overall impact on ACR remains poorly understood.
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may develop end-stage lung disease requiring transplantation. We report the clinical course, pulmonary pathology radiographic correlation, and outcomes after transplantation in three patients who developed chronic failure due to postacute sequelae of SARS-CoV-2 infection.
BackgroundDonation after circulatory death with thoracoabdominal normothermic regional perfusion (DCD-NRP) for cardiac transplant has promising results, though data lung is lacking. This study evaluates outcomes using DCD-NRP allografts.MethodsAll patients who underwent transplantation (LT) from June 1, 2020, to July 5, 2023, at a single institution were evaluated. Recipients received organs or brain dead (control) donors (donation (DBD)). All adult, primary bilateral LT (BLT) without...
Background. Cardiovascular disease is the leading cause of premature mortality in autosomal dominant polycystic kidney (ADPKD). We examined peripheral augmentation index (AIx) as a measure systemic vascular function and circulating markers inflammation patients with ADPKD.
Opioid analgesics are commonly used post-lung transplant, but have many side effects and associated with worse outcomes. We conducted a retrospective review of all lung transplant recipients who were treated multimodal opioid-sparing pain protocol. The use liposomal bupivacaine intercostal nerve block was variable due to hospital restrictions. primary objective describe opioid requirements patient-reported scores early assess the impact intraoperative block. 64 our utilization decreased mean...
Little is known about the effects of hepatitis C viremia on immunologic outcomes in era direct-acting antivirals. We conducted a prospective, single-arm trial lung transplantation from C-infected donors into C-naïve recipients (n = 21). Recipients were initiated glecaprevir-pibrentasvir immediately post-transplant and continued therapy for total 8 weeks. A control group C-negative lungs matched 1:1 baseline variables The primary outcome was frequency acute cellular rejection over 1-year...
[b]BACKGROUND[/b] Morbidity and mortality rates after lung transplantation remain high compared to other solid organ transplants. In the allocation score era, patients given highest priority on waitlist are those with greatest severity of illness, who often require preoperative hospitalization. [b]MATERIAL AND METHODS[/b] To determine association pre-transplant hospitalization post-transplant outcomes, we retrospectively evaluated 448 transplant recipients at our center between January 2010...