A5029316781- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Long-Term Effects of COVID-19
- Anesthesia and Sedative Agents
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Hospital Admissions and Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Patient Safety and Medication Errors
- Transplantation: Methods and Outcomes
- Hemodynamic Monitoring and Therapy
- Healthcare Technology and Patient Monitoring
- Geriatric Care and Nursing Homes
- Disaster Response and Management
- Child Nutrition and Feeding Issues
- Nursing Diagnosis and Documentation
- Non-Invasive Vital Sign Monitoring
- Nursing education and management
- Focus Groups and Qualitative Methods
New York Hospital Queens
2013-2025
NewYork–Presbyterian Hospital
2013-2025
Columbia University Irving Medical Center
2016-2024
Columbia University
2006-2023
Pulmonary and Allergy Associates
2021
Presbyterian Hospital
2015-2020
New York Academy of Medicine
2020
University of Virginia
2020
Kaiser Permanente San Francisco Medical Center
2020
Over 40 000 patients with COVID-19 have been hospitalised in New York City (NY, USA) as of April 28, 2020. Data on the epidemiology, clinical course, and outcomes critically ill this setting are needed.
Rationale: Two distinct subphenotypes have been identified in acute respiratory distress syndrome (ARDS), but the presence of subgroups ARDS associated with coronavirus disease (COVID-19) is unknown. Objectives: To identify clinically relevant, novel COVID-19-related and compare them previously described subphenotypes. Methods: Eligible participants were adults COVID-19 at Columbia University Irving Medical Center. Latent class analysis was used to baseline clinical, respiratory, laboratory...
Abstract Background Nearly 30,000 patients with coronavirus disease-2019 (COVID-19) have been hospitalized in New York City as of April 14 th , 2020. Data on the epidemiology, clinical course, and outcomes critically ill COVID-19 this setting are needed. Methods We prospectively collected clinical, biomarker, treatment data adults laboratory-confirmed-COVID-19 admitted to two hospitals northern Manhattan between March 2 nd 1 st The primary outcome was in-hospital mortality. Secondary...
Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support, despite growing implementation of ECMO ARDS in the general population.
Lung-protective ventilation strategies are the current standard of care for patients with acute respiratory distress syndrome in an effort to provide adequate ventilatory requirements while minimizing ventilator-induced lung injury. Some may benefit from ultra-lung-protective ventilation, a strategy that achieves lower airway pressures and Vt than standard. Specific physiological parameters beyond severity hypoxemia, such as driving pressure system elastance, be predictive those most likely...
The determinants of immunoglobulin G (IgG) level and the risk hypogammaglobulinemia (HGG) in patients with severe lung disease before after transplantation are unknown.
In Abelson murine leukemia virus (A-MuLV)-transformed cells, members of the Janus kinase (Jak) family non-receptor tyrosine kinases and signal transducers activators transcription (STAT) signaling proteins are constitutively activated. these v-Abl oncoprotein Jak physically associate. To define molecular mechanism constitutive Jak-STAT in functional significance v-Abl–Jak association was examined. Mapping Jak1 interaction domain demonstrates that amino acids 858 to 1080 within...
Background: Little is known about the actual treatment of patients with chronic obstructive pulmonary disease (COPD), either in inpatient or outpatient settings. We hypothesized that there are substantial opportunities for improvement adherence current guidelines and recommendations. Methods: reviewed medical records all hospitalized acute exacerbation COPD between January 2005 December 2006 at 5 New York City hospitals. Results: There were 1285 unique 1653 hospitalizations. Of these 1653,...
Introduction Survivors of critical illness face many potential long-term sequelae. Prior studies showed that early rehabilitation in the intensive care unit (ICU) reduces physical impairment and decreases ICU hospital length stay (LOS). However, these are based on a single or were conducted with small subset all patients. We examined effect an program concurrently implemented multiple ICUs LOS. Methods An was systematically five at sites two affiliated academic institutions. retrospectively...
Rationale: Early mobilization of extracorporeal membrane oxygenation (ECMO)-supported patients is increasingly common, but it remains unknown whether there are factors predictive achieving higher intensity among those able to participate in physical therapy. Additionally, data regarding the safety and feasibility early with femoral cannulation, particularly ambulation, sparse. Objectives: To determine associated out-of-bed versus in-bed therapy ECMO-supported participating therapy,...
Abstract Introduction In order to be positioned address the increasing strain of burnout and worsening nurse shortage, a better understanding factors that contribute nursing workload is required. This study aims examine difference between order‐based clinically perceived workloads quantify higher workload. Design A retrospective cohort was used on an observational dataset. Methods We combined patient flow, staffing assignment, intensity data multivariate linear regression analyze how various...
Over the past decade, continuous flow left ventricular assist devices (CF-LVADs) have become mainstay of therapy for end stage heart failure. While number patients on support is exponentially growing, at present there are no American Heart Association or European Society Cardiology Advanced Cardiovascular Life Support guidelines management this unique patient population. We propose an algorithm hospitalized unresponsive CF-LVAD outside intensive care unit setting. Key elements are: creation...
Studies suggest a pathogenic role of endothelial dysfunction in chronic obstructive lung disease (COPD). Omega-3 (n-3) polyunsaturated fatty acid (PUFA) supplementation improves function other diseases but has not been examined COPD.We hypothesized that n-3 PUFA would improve systemic COPD. We performed pilot randomized, placebo-controlled, double-blind, phase 2 superiority trial (NCT00835289).Adults with moderate and severe stable COPD (79% emphysema on computed tomography [CT]) were...
To the Editor: As coronavirus disease 2019 (COVID-19) spreads across New York, it became apparent that there were not enough ICU beds, ventilators, or staff to accommodate patients flowing in through our emergency rooms. NewYork-Presbyterian (NYP) is one of largest healthcare delivery systems United States, inclusive two large academic medical centers (Columbia University Irving and Weill Cornell), six regional hospitals serving some hardest hit areas during pandemic, nation's leading...
It is unknown how hospital- and systems-level factors have impacted patient safety in the intensive care unit (ICU) during COVID-19 pandemic. We sought to understand pandemic has exacerbated preexisting issues created novel challenges ICUs United States.We performed a national, multi-institutional, mixed-methods survey of critical clinicians elicit experiences related The was disseminated via email through Society Critical Care Medicine listserv. Data were reported as valid percentages,...
The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed to COVID-19 been debated due uncertain survival benefit and the resources required safely deliver ECMO support. We retrospectively investigated adult supported at our institution during first 80 days following New York City's declaration a state emergency. primary...
Background Delirium is a common, underdetected problem that has short- and long-term negative sequelae for critically ill patients. Prompt accurate delirium identification by nurses can ensure early intervention treatment to help minimize adverse outcomes. Objectives To evaluate the relationship between an educational program accuracy of registered nurses' (RNs') documentation Confusion Assessment Method Intensive Care Unit (CAM-ICU), screening tool. Methods In medical ICU at tertiary...
The use of extracorporeal membrane oxygenation in the management ARDS has grown considerably past decade, largely as a consequence improvements technology and techniques. Recently published data helped clarify ECMO ARDS, its role optimizing lung-protective ventilation minimizing ventilator-induced lung injury potential to have substantial impact on outcomes. In future, novel strategies may lead new paradigm our approach patients with ARDS.