A5043477017- Long-Term Effects of COVID-19
- Bacterial Infections and Vaccines
- Mosquito-borne diseases and control
- Infectious Encephalopathies and Encephalitis
- Peripheral Neuropathies and Disorders
- Infectious Diseases and Tuberculosis
- COVID-19 Clinical Research Studies
- Cytomegalovirus and herpesvirus research
- Autoimmune Neurological Disorders and Treatments
- Malaria Research and Control
- Herpesvirus Infections and Treatments
- Tuberculosis Research and Epidemiology
- Fungal Infections and Studies
- COVID-19 and Mental Health
- Viral Infections and Immunology Research
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Vectors
- Antifungal resistance and susceptibility
- HIV Research and Treatment
- Vector-borne infectious diseases
- HIV-related health complications and treatments
- Epilepsy research and treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Polyomavirus and related diseases
New York Hospital Queens
2019-2025
Columbia University
2015-2025
NewYork–Presbyterian Hospital
2018-2025
Columbia University Irving Medical Center
2017-2025
Columbia College
2020-2025
Royal College of Physicians
2020-2025
University of Zambia
2015-2023
Johns Hopkins University
2013-2023
University of Rochester Medical Center
2023
University of Maryland, Baltimore
2015-2023
Many patients with SARS-CoV-2 infection develop neurological signs and symptoms; although, to date, little evidence exists that primary of the brain is a significant contributing factor. We present clinical, neuropathological molecular findings 41 consecutive infections who died underwent autopsy in our medical centre. The mean age was 74 years (38-97 years), 27 (66%) were male 34 (83%) Hispanic/Latinx ethnicity. Twenty-four (59%) admitted intensive care unit. Hospital-associated...
the New York State Department of Health (NYSDOH) notified CDC detection poliovirus type 2 in stool specimens from an unvaccinated immunocompetent young adult Rockland County, York, who was experiencing acute flaccid weakness.The patient initially experienced fever, neck stiffness, gastrointestinal symptoms, and limb hospitalized with possible myelitis (AFM).Vaccine-derived (VDPV2) detected obtained on days 11 12 after initial symptom onset.To date, related Sabin-like polioviruses have been...
To identify the rates of neurological events following administration mRNA (Pfizer, Moderna) or adenovirus vector (Janssen) vaccines in U.S..
To describe a case series of adult patients in the intensive care unit super-refractory status epilepticus (SRSE; refractory lasting 24 hours or more despite appropriate anesthetic treatment) who received treatment with ketogenic diet (KD).We performed retrospective review at 4 medical centers SRSE treated KD. Data collected included demographic features, clinical presentation, diagnosis, EEG data, anticonvulsant treatment, and timing duration Primary outcome measures were resolution (SE)...
To investigate predictors of outcome in patients with all-cause encephalitis receiving care the intensive unit.A retrospective analysis cases at The Johns Hopkins Hospital and Bayview Medical Center was performed. Using multivariate logistic regression analysis, we examined mortality good (defined as modified Rankin Scale scores 1-3) poor (scores 4 5) those surviving to hospital discharge.In our cohort 103 patients, median age 52 years (interquartile range 26), (50.49%) were male, 28...
Abstract We document the neuropathologic findings of a 73-year old man who died from acute cerebellar hemorrhage in context relatively mild SARS-CoV2 infection. The patient developed sudden onset headache, nausea, and vomiting, immediately followed by loss consciousness on day admission. Emergency medical services found him severely hypoxemic at home, suffered cardiac arrest during transport to emergency department. team achieved return spontaneous circulation after over 17 min...
Currently, there are over 1.9 million confirmed cases of coronavirus disease 2019 (COVID-19) globally with 590,000 in the United States.1 The number COVID-19–positive children States is unknown. A report summarizing 72,314 COVID-19 from Chinese Center for Disease Control and Prevention noted 416 younger than 10.2 An observational study at Wuhan Children's Hospital 31 1 year youngest case a 1-day-old.3 Cases were largely characterized by upper respiratory tract infection or pneumonia, fever,...
Objective: To assess the clinical utilization and performance of FilmArray® Meningitis/Encephalitis (ME) multiplex polymerase chain reaction (PCR) panel in a hospital setting. Background: Rapid diagnosis treatment central nervous system (CNS) infections are critical to reduce morbidity mortality. The ME is Food Drug Administration (FDA) approved rapid PCR assay that targets 14 bacteria, viruses, fungi. Previous studies show an overall agreement 93-99% between conventional diagnostic testing....
The presence in cerebrospinal fluid of antibodies to EV peptides at higher levels than non-AFM controls supports the plausibility a link between infection and AFM that warrants further investigation has potential lead strategies for diagnosis prevention disease.
A review of 15 patients who tested positive for human herpesvirus 6 (HHV-6) on the FilmArray Meningitis/Encephalitis panel revealed that majority were unlikely to have HHV-6 encephalitis. Criteria assist interpretation results are presented.
Background. The 2012 outbreak of fungal meningitis associated with contaminated methylprednisolone produced by a compounding pharmacy has resulted in >750 infections. An important question facing patients and clinicians is the duration antifungal therapy. We evaluated (1-3)-β-d-glucan (BDG) as marker for monitoring response to treatment. Methods. determined sensitivity specificity BDG testing using Fungitell assay, 41 cerebrospinal fluid (CSF) specimens from confirmed cases 66 negative...
In 1891, Winter1 described the first 4 cases of tuberculous meningitis (TBM), in which "paracenteses theca vertebralis was performed to relieve cerebrospinal fluid (CSF) pressure." Since this original description lumbar puncture (LP) procedure, neurologists worldwide have relied on LPs for both diagnostic and therapeutic purposes. resource-limited settings, are often only neurologic test available aid clinician diagnosis. sub-Saharan Africa, a large number patients present hospitals with...
Over 900 travel-associated Zika virus cases have been identified in New York City (NYC), York. A survey was administered NYC adapted from the Knowledge, Attitudes, and Practices (KAP) on developed by World Health Organization (WHO). standardized, self-administered, anonymous questionnaire to a convenience sample Manhattan Bronx June 30th, 2016 October 21st, 2016. Responses were grouped into six domains based content structure of questions summarized using descriptive statistics or converted...
Beginning in December 2019, a novel coronavirus, SARS-CoV-2 (COVID-19), began spreading rapidly throughout China and now is global pandemic, with cases reported over 192 countries territories worldwide. Clinically, COVID-19 ranges from mild, self-limiting respiratory illness to severe progressive pneumonia multiorgan failure. The first case was at the beginning of March New York City (NYC), just 3 weeks later, NYC its suburbs have 5% cases. Worldwide, there rapid increase number daily,...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, characterized predominantly by symptoms, has affected a small subset of children. Neurologic manifestations have been described in adults, including encephalitis/meningitis, encephalopathy, strokes, seizures, and anosmia,1,2 but there are few reports neurologic children with SARS-CoV-2.3