Maki Umino

ORCID: 0000-0002-0732-7212
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cerebrovascular and Carotid Artery Diseases
  • Advanced MRI Techniques and Applications
  • Parkinson's Disease Mechanisms and Treatments
  • Meningioma and schwannoma management
  • Dementia and Cognitive Impairment Research
  • Vascular Malformations Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Neurological disorders and treatments
  • Neurological and metabolic disorders
  • Polyomavirus and related diseases
  • Cerebral Venous Sinus Thrombosis
  • Intracranial Aneurysms: Treatment and Complications
  • MRI in cancer diagnosis
  • Neurological Disease Mechanisms and Treatments
  • Multiple Sclerosis Research Studies
  • Medical Imaging Techniques and Applications
  • Long-Term Effects of COVID-19
  • Fetal and Pediatric Neurological Disorders
  • Ear and Head Tumors
  • Full-Duplex Wireless Communications
  • Cervical and Thoracic Myelopathy
  • RNA regulation and disease

Mie University
2016-2025

Mie University Hospital
2019

Background/Objectives: A subtype of cerebral amyloid angiopathy (CAA), iatrogenic CAA (iCAA), has been increasingly reported. iCAA occurs primarily in patients who underwent surgery during childhood and is caused by the prion-like propagation beta. This tends to develop at a younger age than age-related CAA, usually before 55. After latency period 20–40 years following surgery, it manifests as lobar intracerebral hemorrhage (ICH), cognitive impairment, or transient focal neurological...

10.3390/neurolint17050064 article EN cc-by Neurology International 2025-04-24

Abstract Catheter ablation is an important non-pharmacological intervention for atrial fibrillation (AF), but its effect on the incidence of asymptomatic cerebral emboli and long-term effects cognitive function remain unknown. We prospectively enrolled 101 patients who underwent AF ablation. Brain magnetic resonance imaging (MRI) (72 patients) neuropsychological assessments (66 were performed 1–3 days (baseline) 6 months after Immediately ablation, diffusion-weighted MRI 3-dimensional double...

10.1038/s41598-021-98484-w article EN cc-by Scientific Reports 2021-09-23

Background and Purpose- Cortical microinfarcts (CMIs) are small ischemic lesions found in cerebral amyloid angiopathy (CAA) embolic stroke. This study aimed to differentiate CMIs caused by CAA from those microembolisms, using 3-Tesla magnetic resonance imaging. Methods- We retrospectively investigated 70 patients with at least 1 cortical infarct <10 mm on 3-dimensional double inversion recovery Of the patients, 43 had an stroke history (Emboli-G) while 27 CAA-group. compared size, number,...

10.1161/strokeaha.119.028202 article EN Stroke 2019-12-23

Multinodular and vacuolating neuronal tumor (MVNT) is a relatively new disease concept proposed in 2013 was classified as separate type 2021 by the World Health Organization (WHO) classification. MVNT can cause seizures but benign disease, with no cases of enlargement or postoperative recurrence reported. Recent reports described advanced MRI features cases, diagnosis usually based on characteristic findings clusters nodules. Here, we report multiparametric FDG-PET/CT case epileptiform...

10.1016/j.radcr.2023.06.002 article EN cc-by-nc-nd Radiology Case Reports 2023-06-16

Abstract Objectives Cerebral microbleeds ( CMB s) are often observed in memory clinic patients. It has been generally accepted that deep s (D‐ result from hypertensive vasculopathy HV ), whereas strictly lobar SL ‐ cerebral amyloid angiopathy CAA ) which frequently coexists with Alzheimer's disease AD ). Mixed (M‐ have partially attributed to and also . The aim of this study was elucidate the differences between M‐ terms clinical features regional distribution. Materials We examined 176...

10.1002/brb3.856 article EN cc-by Brain and Behavior 2017-10-16

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Since the advent of magnetic resonance imaging technology, cerebral microbleeds can be diagnosed in vivo. However, underlying mechanism microbleed formation is not fully understood. &lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; This study aimed to identify factors associated with after carotid artery stenting (CAS). &lt;b&gt;&lt;i&gt;Method:&lt;/i&gt;&lt;/b&gt; We retrospectively examined 125 patients who underwent CAS for stenosis....

10.1159/000500112 article EN cc-by-nc-nd Cerebrovascular Diseases Extra 2019-06-14

Purpose: Deep brain stimulation (DBS) is an established therapy for Parkinson's disease (PD). However, deteriorating cognitive function after DBS a considerable problem affected patients. This study was undertaken to predict worsening based on pulvinar findings in susceptibility-weighted imaging (SWI). Methods: We examined 21 patients with PD who underwent along SWI and neuromelanin-sensitive MR (NMI). further assessed hypointensity findings, as well the area of substantia nigra (SN) pars...

10.3389/fneur.2019.01158 article EN cc-by Frontiers in Neurology 2019-10-31

Abstract Vertebral artery dissection and recurrent meningitis are rare complications in Behçet's disease. disease may be associated with familial Mediterranean fever. Here, we describe a 52‐year‐old woman severe headache who exhibited vertebral dissection. Cerebrospinal fluid showed high levels of interleukin‐6. Magnetic resonance imaging revealed right The patient had three heterozygous mutations the fever gene ( MEFV ) gene. She fulfilled criteria for diagnosis In conclusion, cause...

10.1002/acn3.773 article EN cc-by-nc-nd Annals of Clinical and Translational Neurology 2019-04-04

Background: Hypertensive arteriopathy (HA) and cerebral amyloid angiopathy (CAA) may contribute to the development of mixed microbleeds (CMBs). Recently, total small vessel disease (SVD) scores for HA CAA were proposed, which are determined by a combination MRI markers reflect overall severity these microangiopathies. Objective: We investigated whether or not HA-SVD CAA-SVD could be used predict overlap in patients with CMBs. Methods: Fifty-three subjects CMBs retrospectively analyzed....

10.3233/jad-200992 article EN Journal of Alzheimer s Disease 2020-11-13

We describe a case series of suspected metallic embolism after coil embolization for intracranial aneurysms. Between January 2012 and December 2014, 110 aneurysms had been treated by in our institution. In 6 cases, the postprocedural MR imaging revealed abnormal spotty lesions not detected on preprocedural imaging. The were also undetectable CT scan. They demonstrated as low-intensity spots T1WI, T2WI, DWI, T2*-weighted On they accompanied bright "halo," imaging, showed "blooming" effect. 3...

10.3174/ajnr.a4804 article EN cc-by American Journal of Neuroradiology 2016-04-21

A rosette-forming glioneuronal tumor (RGNT) is a rare and slow-growing central nervous system tumor. This usually assessed by MRI during the follow-up period. RGNT can show alteration of contrast enhancement regardless growth. Here, we report case arising from pons which shows partial on initial MRI, smaller at 10 months, totally disappeared 18 months without any therapy.

10.1016/j.radcr.2019.05.011 article EN cc-by-nc-nd Radiology Case Reports 2019-05-22

Abstract Background and purpose Cortical microinfarcts (CMIs) are frequently found in the brains of patients with advanced cerebral amyloid angiopathy (CAA) at autopsy. The small vessel disease (SVD) score for CAA (i.e., CAA‐SVD score) has been proposed to evaluate severity CAA‐associated vasculopathic changes by a combination magnetic resonance imaging (MRI) markers. aim this study was examine association between total features CMIs on vivo 3‐Tesla MRI. Methods Eighty probable were...

10.1111/ene.14610 article EN European Journal of Neurology 2020-10-24

Abstract We aimed to assess the combined diagnostic value of apparent diffusion coefficient (ADC) and tumor blood flow (TBF) obtained by pseudocontinuous arterial spin labeling (pCASL) for differentiating malignant tumors (MTs) in salivary glands from pleomorphic adenomas (PAs) Warthin’s (WTs). used pCASL imaging ADC map evaluate 65 patients, including 16 with MT, 30 PA, 19 WT. evaluated all histogram analyses compared various characteristics one-way analysis variance followed Tukey post-hoc...

10.1038/s41598-022-09968-2 article EN cc-by Scientific Reports 2022-04-08
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