A5067194755- Drug Transport and Resistance Mechanisms
- Analytical Methods in Pharmaceuticals
- Pharmacogenetics and Drug Metabolism
- Agriculture, Soil, Plant Science
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical studies and practices
- Pharmacological Effects and Toxicity Studies
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Coal and Its By-products
- Tribology and Lubrication Engineering
- Nanoparticle-Based Drug Delivery
- Effects and risks of endocrine disrupting chemicals
- Pharmacological Effects of Natural Compounds
- Inflammatory mediators and NSAID effects
- Analytical Chemistry and Chromatography
- RNA Interference and Gene Delivery
- Magnetic Bearings and Levitation Dynamics
- Phytochemistry and Biological Activities
- Ecology and Conservation Studies
- Phosphorus and nutrient management
- Per- and polyfluoroalkyl substances research
- Clay minerals and soil interactions
- Natural product bioactivities and synthesis
- Advancements in Transdermal Drug Delivery
Chonnam National University
2015-2024
Gyeongsang National University
2012-2024
Chonnam National University Hospital
2006-2023
Pusan National University
2016
Rural Development Administration
2010-2016
Korea Institute of Science and Technology
2005-2016
National NanoFab Center
2016
Dr.Chung’s Food (South Korea)
2015
Seoul National University of Education
2008-2015
National Academy of Agricultural Science
2009-2013
A new composite consisting of TiO2 nanotubes and CdS nanoparticles, where particles bind covalently to the titania surface through a bifunctional organic linker, was successfully fabricated; this nanotube-based shows enhanced photocatalytic activity under visible-light irradiation.
Methotrexate (MTX) is a folic acid antagonist used as an effective drug to treat various kinds of cancers. However, MTX has limited use in cancer chemotherapy due its adverse effects such poor bioavailability, low specificity, resistance, and dose-dependent side effects. To improve lymphatic delivery reduce toxicity MTX, MTX-loaded nanoparticles (NPs) were prepared the present study. NPs with double emulsion solvent evaporation method using poly(lactide-co-glycolide) (PLGA). assessed for...
This paper describes a general approach for transferring clean single-layer graphene onto silicon nitride nanopore devices and the use of electron beam transmission microscope (TEM) to drill size-controlled nanopores in freely suspended graphene. Besides drilling, we also used TEM heal completely close unwanted secondary holes formed by damage during drilling process. We demonstrate assisted shrinking irregularly shaped 40-60 nm pores down 2 nm, exhibiting an exquisite control diameter. Our...
The objective of this study was to evaluate the adsorption characteristics malachite green (MG) on pristine lignin as a dye adsorbent. capacity MG (31.2 mg/g) described by Langmuir isotherm and pseudo second order models, were higher than humic acid (6.4 mg/g). rapid occurring within 15 min reaction, then equilibrium reached. based an intraparticle diffusion model indicated that it dominated external boundary. Removal can be applied at wide range pH's (2–5), optimal dosage for removal 3 g/L....
The objectives of this research were to evaluate antioxidant activities and nutritional components, including phenolic acid, catechin, organic sugar, amino persimmon juice from persimmons grown in different regions around Korea. Persimmon (Diospyros kaki) exhibits potent effects DPPH, ABTS, reducing power, FRAP methods analysis. levels constituents showed significant differences among all the samples. In particular, tartaric glucose, gallic epicatechin gallate aspartic acid observed be...
Quercetin is a flavonol believed to have beneficial effects on human health. Rutin, found in many plants, fruits and vegetables, metabolized by intestinal bacteria converted quercetin, where it absorbed through the epithelium. This study aimed isolate characterize capable of converting rutin quercetin. A bacterium that can metabolize was isolated from faecal samples identified 16S rRNA gene sequencing. The whole-cell enzymatic activities flavonoid glycoside conversion profiles were also...
Solid-self-emulsifying drug delivery system (S-SEDDS) of paclitaxel (Ptx) was developed by the spray drying method with purpose improving low bioavailability (BA) Ptx. 10% oil (ethyl oleate), 80% surfactant mixture (Tween 80 : Carbitol, 90 10, w/w), and cosolvent (PEG 400) were chosen according to their solubilizing capacity. The mean droplet size, zeta potential, encapsulation efficiency prepared S-SEDDS 16.9 ± 1.53 nm, 12.5 1.66 mV, 56.2 8.1%, respectively. In S-SEDDS, Ptx presents in form...
Abstract Veterinary antibiotics (VAs) administered to livestock are introduced into the soil through manure and compost. These can run off surface water or leach groundwater during rainfall, causing problems such as antibiotic contamination occurrence of antibiotic-resistant bacteria. In this study, an analytical method for detecting four classes VAs (penicillin, tetracyclines, macrolides, sulfonamides) in river was developed, residual agricultural environment monitored. Soil samples were...
Bi-functional nanoparticles (NPs) that consist of silica-coated magnetic cores and luminescent lanthanide (Ln) ions anchored on the silica surface via organic linker molecules are reported. Compared to individual Ln ions, hybrid NPs show a drastically enhanced photoluminescence due efficient ligand-to-metal energy transfer in Ln-loaded NPs: new bi-functional could be used variety biological applications involving separation optical detection.
Orientia tsutsugamushi induces vasculitis leading to symptoms of systemic organ invasion including meningitis and meningoencephalitis. We conducted a retrospective case-control study scrub typhus patients investigate the clinical laboratory features with or meningoencephalitis, therapeutic outcomes, determine predictor factors. Cases were 22 controls 303 without Multivariate analysis showed that presence pneumonitis was associated occurrence meningoencephalitis (odds ratio [OR] 8.9; P <...
Research on the occurrence of perfluorochemicals (PFCs) such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic (PFOA) in agricultural environment is lacking, spite their potential risk via food chain transfer from aquatic soil-plant systems to animals and/or humans. In present study, for first time, soil water samples collected 243 different sites adjacent waste treatment plants (WWTPs) belonging 81 cities 5 provinces with levels industrialization South Korea were monitored...
Methotrexate, which is widely used in the treatment of cancer and immune-related diseases, has limitations use because its low bioavailability, short half-life, tissue toxicity. Thus, this study, a nano-sized water-in-oil-in-water (W/O/W) double emulsion containing methotrexate was prepared to enhance lymphatic delivery bioavailability. Based on results from solubility testing pseudo-ternary diagram olive oil as oil, Labrasol surfactant, ethanol co-surfactant, were selected optimal...