Amy Langdon

ORCID: 0000-0002-0797-8939
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About
Contact & Profiles
Research Areas
  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health
  • Nosocomial Infections in ICU
  • Gastrointestinal motility and disorders
  • Diet and metabolism studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Child Nutrition and Water Access
  • Mycobacterium research and diagnosis
  • Clinical Nutrition and Gastroenterology
  • Genomics and Phylogenetic Studies
  • Helicobacter pylori-related gastroenterology studies
  • Heart Rate Variability and Autonomic Control
  • Chromosomal and Genetic Variations
  • Nutritional Studies and Diet
  • Delphi Technique in Research
  • Hallucinations in medical conditions
  • Psychosomatic Disorders and Their Treatments
  • Microbial Community Ecology and Physiology
  • Food Security and Health in Diverse Populations
  • Plant Ecology and Soil Science
  • Microbial Fuel Cells and Bioremediation
  • Genomic variations and chromosomal abnormalities
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Metal Extraction and Bioleaching

Washington University in St. Louis
2016-2023

Flinders University
2023

University of Nottingham
2023

The University of Adelaide
2023

Brigham and Women's Hospital
2013

Bigelow Laboratory for Ocean Sciences
2011

Swarthmore College
2011

Abstract Background Once antibiotic-resistant bacteria become established within the gut microbiota, they can cause infections in host and be transmitted to other people environment. Currently, there are no effective modalities for decreasing or preventing colonization by bacteria. Intestinal microbiota restoration prevent Clostridioides difficile infection (CDI) recurrences. Another potential application of is suppression non- C. multidrug-resistant overall decrease abundance antibiotic...

10.1186/s13073-021-00843-9 article EN cc-by Genome Medicine 2021-02-16

Leptothrix ochracea is a common inhabitant of freshwater iron seeps and iron-rich wetlands. Its defining characteristic copious production extracellular sheaths encrusted with oxyhydroxides. Surprisingly, over 90% these are empty, hence, what appears to be an abundant population iron-oxidizing bacteria, consists relatively few cells. Because L. has proven difficult cultivate, its identification based solely on habitat preference morphology. We utilized cultivation-independent techniques...

10.1371/journal.pone.0017769 article EN cc-by PLoS ONE 2011-03-17

Significance Genomic structural variants (SVs) significantly contribute to human genetic variation and have been linked with numerous diseases. Compared humans, the characterization of SVs occurring within across nonhuman primates has lagged. We generated comprehensive massively parallel DNA sequencing-based SV maps in three primate species show that rates different formation mechanisms, such as nonallelic homologous recombination Alu retrotransposition, vary between great apes rhesus...

10.1073/pnas.1305904110 article EN Proceedings of the National Academy of Sciences 2013-09-06

The effect of postural orthostatic tachycardia syndrome (POTS) on health-related quality life (HrQoL) remains poorly studied. Here, we sought to compare the HrQoL in individuals with POTS a normative age-/sex-matched population.Participants enrolled Australian registry between 5 August 2021 and 30 June 2022 were compared propensity-matched local population data from South Health Omnibus Survey. EQ-5D-5L instrument was used assess across five domains (mobility, self-care, usual activities,...

10.1007/s10286-023-00955-9 article EN cc-by Clinical Autonomic Research 2023-06-20

The spread of multidrug resistance among pathogenic organisms threatens the efficacy antimicrobial treatment options. human gut serves as a reservoir for many drug-resistant and their genes, perturbation microbiome by exposure can open metabolic niches to resistant pathogens. Once established in gut, antimicrobial-resistant bacteria persist even after ceases. Strategies prevent multidrug-resistant organism (MDRO) infections are scarce, but autologous fecal microbiota transplantation...

10.1128/mspheredirect.00588-18 article EN cc-by mSphere 2018-11-20

Children with severe acute malnutrition are treated antibiotics as outpatients. We aimed to determine the effect of 7 days amoxicillin on and long-term changes gut microbiome antibiotic resistome in children for malnutrition.

10.1016/s2666-5247(23)00213-6 article EN cc-by The Lancet Microbe 2023-10-19

Abstract Introduction Dementia and hearing loss (HL) are becoming increasingly prevalent in society commonly co-exist. People living with concurrent conditions have complex needs face additional barriers to diagnosis management. There is a paucity of research regarding the current optimal management HL people dementia. This aimed to: (1) examine clinical provision for dementia within UK audiology services, (2) explore recommendations co-existing from professionals these conditions. Methods...

10.1093/ageing/afad104.060 article EN Age and Ageing 2023-07-01

An amendment to this paper has been published and can be accessed via the original article.

10.1186/s13073-021-00846-6 article EN cc-by Genome Medicine 2021-02-12

OBJECTIVES/SPECIFIC AIMS: Clostridium difficile is the most common cause of infectious antibiotic associated diarrhea. It often refractory to antimicrobial therapy and fecal microbiota transplantation (FMT) emerging as a therapeutic option. The objective characterize direct effects FMT on gut microbiota. METHODS/STUDY POPULATION: Fecal specimens were obtained from cohort 29 subjects with recurrent C. infection who received FMTs 1 4 healthy donors part phase 2 trial (Rebiotix). collected...

10.1017/cts.2017.130 article EN cc-by-nc-nd Journal of Clinical and Translational Science 2017-09-01

OBJECTIVES/SPECIFIC AIMS: A course of oral broad-spectrum antibiotics frequently has a positive effect on morbidity and mortality in severe acute malnutrition (SAM), but the actual mechanism for this is unknown. This especially important to find quantify because possibility that using prophylactically may accelerate danger from antibiotic resistant infections. study aims answer (1) how therapy improves nutritional recovery (2) much it affects prevalence resistance genes microbiome....

10.1017/cts.2018.179 article EN cc-by-nc-nd Journal of Clinical and Translational Science 2018-06-01
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