A5004565989- Health Systems, Economic Evaluations, Quality of Life
- Palliative Care and End-of-Life Issues
- Pain Management and Opioid Use
- Geriatric Care and Nursing Homes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intergenerational Family Dynamics and Caregiving
- Health disparities and outcomes
- Cancer survivorship and care
- Global Health Care Issues
- Intensive Care Unit Cognitive Disorders
- Diet and metabolism studies
- Economic and Financial Impacts of Cancer
- Dementia and Cognitive Impairment Research
- Pediatric Pain Management Techniques
- Healthcare cost, quality, practices
- Delphi Technique in Research
- Pancreatic and Hepatic Oncology Research
- Healthcare Policy and Management
- Intestinal and Peritoneal Adhesions
- Respiratory Support and Mechanisms
- Epilepsy research and treatment
- Patient-Provider Communication in Healthcare
- Anesthesia and Sedative Agents
- Family Support in Illness
- Childhood Cancer Survivors' Quality of Life
Cancer Council Victoria
2020-2025
Deakin University
2017-2025
National Council for Palliative Care
2022
Flinders University
2009-2018
University of Technology Sydney
2018
Repatriation General Hospital
2013-2016
North Yorkshire County Council
2012
Child, Adolescent and Family Mental Health
2010
Dublin City University
2010
Although a five level version of the widely-used EuroQol 5 dimensions (EQ-5D) instrument has been developed, population norms are not yet available for Australia to inform future valuation health in economic evaluations. The aim this study was estimate HrQOL normative values EQ-5D-5L preference-based measure large, randomly selected, community sample South Australia. included 2013 Australian Health Omnibus Survey, an interviewer-administered, face-to-face, cross-sectional survey. Respondents...
Antipsychotics are widely used for distressing symptoms of delirium, but efficacy has not been established in placebo-controlled trials palliative care.To determine risperidone or haloperidol relative to placebo relieving target delirium associated with distress among patients receiving care.A double-blind, parallel-arm, dose-titrated randomized clinical trial was conducted at 11 Australian inpatient hospice hospital care services between August 13, 2008, and April 2, 2014, participants...
Importance Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing needed. Objective To determine the effect of different doses on worst COPD after 1 week treatment. Design, Setting, Participants Multicenter, double-blind, placebo-controlled randomized clinical trial including (defined as a modified Medical Research Council score 3 to 4)...
Does sertraline provide symptomatic relief for chronic breathlessness in people with advanced disease whose underlying cause(s) are optimally treated? 223 participants (modified Medical Research Council scale ≥2) who had optimal treatment of were randomised 1:1 to 25–100 mg (titrated upwards over 9 days) or placebo 4 weeks. The primary outcome was the proportion an improvement intensity current >15% from baseline on a 100-mm visual analogue scale. responding similar days 26–28 (OR 1.00,...
ABSTRACT Objectives The aim of this study is to estimate the economic burden oral cancer in Australia from societal perspective. Methods population consisted prevalence lip and cavity cancer, other lip, cavity, pharynx cancers for ages 40 years older. Healthcare costs were estimated using 2019–2020 Australian Disease Expenditure Data. Productivity losses disability‐adjusted life years, derived 2019 Global Burden Study gross domestic product per capita. Results annual healthcare approximately...
Evaluating medicinal cannabis in clinical trials is important for informing its efficacy and safety care. Alongside the inherent practical challenges of conducting people receiving palliative care, operationalising with a product requires additional consideration legal, regulatory, ethical, feasibility, pharmacological requirements. This manuscript aims to explore these considerations when Our Phase I/IIb trial examined pharmacokinetic, toxicity secondary (efficacy) outcomes vaporised...
Objective The aim of this study was to evaluate the cost-effectiveness a home-based palliative care model relative usual in expediting discharge or enabling patients remain at home. Design Economic evaluation pilot randomised controlled trial with 28 days follow-up. Methods Mean costs and effectiveness were calculated for Palliative Care Extended Packages Home (PEACH) arms including: home; place death; PEACH intervention costs; specialist service use; acute hospital unit inpatient stays;...
Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration survival. Generic multi-attribute utility values exclude important and non-health outcomes, while partial analyses-where considered separately, their joint relationship under uncertainty ignored-lead incorrect inference regarding preferred strategies.The objective of this paper consider whether such decision making...
This study examined the relationships between a newly developed older person-specific non-preference-based quality of life (QoL) instrument (Older People's Quality Life brief questionnaire (OPQoL-brief)) and two generic preference-based instruments (the EQ-5D-3L Level (EQ-5D-3 L) Adult Social Care Outcomes Toolkit (ASCOT) in community-dwelling population Australian people receiving aged care services. We formulated hypotheses about convergent validity (examined by Wilcoxon-Mann Whitney,...
Background Australian clinical trials are planned to evaluate medicinal cannabis in a range of contexts. Aims To explore the preferences, attitudes and beliefs patients eligible willing consider participation trial for poor appetite appetite‐related symptoms from advanced cancer. Methods A cross‐sectional anonymous survey was administered July December 2015 online eight adult outpatient palliative care and/or cancer services. Respondents were if they ≥18 years, had appetite/taste...
The effect of postural orthostatic tachycardia syndrome (POTS) on health-related quality life (HrQoL) remains poorly studied. Here, we sought to compare the HrQoL in individuals with POTS a normative age-/sex-matched population.Participants enrolled Australian registry between 5 August 2021 and 30 June 2022 were compared propensity-matched local population data from South Health Omnibus Survey. EQ-5D-5L instrument was used assess across five domains (mobility, self-care, usual activities,...
This study evaluates the efficacy of adductor longus tenotomy in athletes with chronic tendinopathy refractory to conservative management. In a retrospective case series we report our experience 109 male who underwent unilateral during period 2000-2005, all whom responded detailed questionnaire. The criterion for was origin pain which prevented training or playing (Level 4), limited 3), affected performance 2)and had failed respond management including rest, rehabilitation and/or local...
Health and social services rely heavily on family friends for caregiving at the end of life.This study sought to determine prevalence factors associated with an unwillingness take role again by interviewing former caregivers palliative care patients.The setting this was South Australia, a population 1.6 million people (7% Australian population) used Omnibus, annual, face-to-face, cross-sectional, whole-of-population, multistage, systematic area sampling survey, which seeks minimum 3000...
Background Urinary mercury concentrations are used in research exploring exposure. Some theorists have proposed that autism is caused by toxicity. We set out to test whether the urine of children with were significantly increased or decreased compared controls siblings. Methods Blinded cohort analyses carried on 56 spectrum disorders (ASD) their siblings (n = 42) and a control sample without ASD mainstream 121) special schools 34). Results There no statistically significant differences...
In Australia, newly initiated, publicly subsidised 'Home-Care Packages' designed to assist older people (≥65 years of age) living in their own home must now be offered on a 'consumer-directed care' (CDC) basis by service providers. However, CDC models have largely developed the absence evidence users' views and preferences. The aim this study was determine what features (attributes) consumer-directed, home-based support services are important informal carers inform design discrete choice...
The study aimed to identify the shared issues and challenges being experienced by staff, their clients informal carers, with introduction of Consumer Directed Care (CDC). Secondary analysis was undertaken data that had been initially collected, via semi-structured in-depth interviews, inform development a discrete choice experiment. raw staff client/carer were re-examined using an iterative inductive process. focused on locating themes differences between participant groups based CDC...