Esmeralda Gracián-Castro

ORCID: 0000-0002-0850-2465
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Dialysis and Renal Disease Management
  • Immunodeficiency and Autoimmune Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Restless Legs Syndrome Research
  • Animal Disease Management and Epidemiology
  • Influenza Virus Research Studies
  • Pharmaceutical studies and practices
  • Tumors and Oncological Cases
  • Infective Endocarditis Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Respiratory viral infections research
  • Diagnosis and treatment of tuberculosis
  • Hidradenitis Suppurativa and Treatments
  • Long-Term Effects of COVID-19
  • Colorectal Cancer Surgical Treatments
  • Autoimmune and Inflammatory Disorders
  • Adolescent and Pediatric Healthcare
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Stoma care and complications
  • Nausea and vomiting management
  • IgG4-Related and Inflammatory Diseases
  • Microbial infections and disease research

Hospital de Especialidades
2023-2024

Mexican Social Security Institute
2024

Texas Biomedical Research Institute
2024

Universidad Popular Autónoma del Estado de Puebla
2023-2024

Universidad Autónoma de Madrid
2019

Hospital Universitario de La Princesa
2019

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2019

Hospital Universitario Lucus Augusti
2012-2017

University Hospital Complex Of Vigo
2016

Hospital Clínico Universitario de Valladolid
2013

Background. The association between bacteremia by Streptococcus gallolyticus subsp. (SGG) and colorectal neoplasia (CRN) is well established but the frequency of varies widely in different studies. We conducted a case-control study to assess SGG CRN.

10.1093/cid/cis434 article EN Clinical Infectious Diseases 2012-05-04

The aims of this study were to assess the risk relapse after discontinuation anti-tumor necrosis factor (anti-TNF) drugs in patients with inflammatory bowel disease (IBD), identify factors associated relapse, and evaluate overcome retreatment same anti-TNF those who relapsed.This was a retrospective, observational, multicenter study. IBD had been treated anti-TNFs whom these discontinued clinical remission achieved included.A total 1,055 included. incidence rate 19% 17% per patient-year...

10.1038/ajg.2016.569 article EN The American Journal of Gastroenterology 2016-12-13

A multistate outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in dairy cows was first reported on March 25, 2024, the United States (US), marking discovery HPAIV cattle. Soon after, a worker an affected farm became human case linked directly to this outbreak. Studies with (IAV) require secondary methods detect infected cells or animal models infection. We modified non-structural (NS) genome segment A/Texas/37/2024 (HPhTX) create recombinant expressing nanoluciferase (HPhTX...

10.1101/2025.03.28.646035 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2025-03-30

Influenza viruses present a significant public health risk, causing substantial illness and death in humans each year. Seasonal flu vaccines must be updated regularly, their effectiveness often decreases due to mismatches with circulating strains. Furthermore, inactivated do not provide protection against shifted influenza that have the potential cause pandemic. The highly pathogenic avian H5N1 clade 2.3.4.4b is prevalent among wild birds worldwide multi-state outbreak affecting poultry...

10.1101/2025.03.28.646033 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2025-03-30

INTRODUCCIÓN: La histiocitosis de células Langerhans (HCL) es una enfermedad rara que afecta múltiples órganos y/o sistemas. No se encuentran descripciones la experiencia en los hospitales mexicanos concentración. OBJETIVO: Describir las características clínicas y respuesta al tratamiento pacientes con HCL un hospital concentración Puebla, México. MÉTODOS: Estudio descriptivo, retrospectivo longitudinal 3er nivel atención médica durante 2014 a 2021. Se revisaron expedientes edad pediátrica...

10.18233/apm.v45i6.2649 article ES cc-by Acta Pediátrica de México 2024-11-20

Introducción: La enfermedad de Parkinson (EP) es un trastorno neurodegenerativo progresivo que afecta múltiples sistemas, manifestándose con síntomas motores y no motores.Los urinarios son las manifestaciones motoras más prevalentes.Objetivo: Comparar la calidad vida (CV) en pacientes EP acuerdo su sintomatología urinaria hospital tercer nivel atención.Método: Estudio comparativo, transversal

10.24875/amh.m24000052 article ES cc-by-nc-nd Anales Médicos de la Asociación Médica del Centro Médico ABC 2024-03-25

Introducción: La enfermedad de Parkinson (EP) es un trastorno neurodegenerativo progresivo que afecta múltiples sistemas, manifestándose con síntomas motores y no motores.Los urinarios son las manifestaciones motoras más prevalentes.Objetivo: Comparar la calidad vida (CV) en pacientes EP acuerdo su sintomatología urinaria hospital tercer nivel atención.Método: Estudio comparativo, transversal

10.24875/amh.m24000069 article ES cc-by-nc-nd Anales Médicos de la Asociación Médica del Centro Médico ABC 2024-05-27

Abstract The host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States. Shortly after, human infection reported a worker Texas following exposure infected cattle. Herein, we rescued cattle-origin influenza A/bovine/Texas/24-029328-02/2024(H5N1, rHPbTX) and A/Texas/37/2024(H5N1, rHPhTX) viruses, identified human, respectively, their low pathogenic forms, rLPbTX rLPhTX, with monobasic HA cleavage sites. Intriguingly, rHPhTX replicated...

10.1101/2024.10.29.620905 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-10-29

The host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States (US). Shortly after, human infection reported a worker Texas following exposure infected cattle. Herein, we rescued cattle-origin influenza A/bovine/Texas/24-029328-02/2024(H5N1, rHPbTX) and A/Texas/37/2024(H5N1, rHPhTX) viruses, identified human, respectively, their low pathogenic forms, rLPbTX rLPhTX, with monobasic HA cleavage sites. Intriguingly, rHPhTX replicated more...

10.1080/22221751.2024.2447614 article EN cc-by-nc Emerging Microbes & Infections 2024-12-27

Knowledge of one's own chronic kidney disease (CKD) can improve long-term quality life (QoL). Peritoneal dialysis presents with residual symptoms that reduce the QoL.

10.5281/zenodo.10278107 article EN PubMed 2024-01-08

Background: The “de-intensification” of anti-TNF therapy in IBD patients with sustained remission may be considered for cost and safety reasons. Our aims were: 1) to evaluate the risk relapse after antiTNF clinical remission; 2) identify predictive factors associated relapse; 3) assess effectiveness a second “re-intensification”; 4) analyze this strategy. Methods: An observational, retrospective multicenter study was performed. Patients Crohn's disease (CD) ulcerative colitis (UC) who...

10.1093/ecco-jcc/jjx002.452 article EN Journal of Crohn s and Colitis 2017-01-26

adipose tissue (VAT) is the compartment most strongly associated with chronic inflammation and further intestinal expansion described as 'creeping fat' well recognised from surgical specimens a hallmark of CD.Aims: to measure body composition in paediatric CD, specifically quantify VAT using magnetic resonance imaging (MRI).Methods: Children (7-18 years) CD healthy children act controls, were recruited.Volumes (expressed litres) abdominal compartments VAT, subcutaneous (SCA), muscle,...

10.1093/ecco-jcc/jjw019.639 article EN Journal of Crohn s and Colitis 2016-03-01

Methods: We conducted a cross-sectional study of s-IFX in all IFXtreated children with IBD (n = 45, Crohn's disease [CD] 32 and ulcerative colitis [UC] 13) 2 Swedish counties, Stockholm Vasteras.The were on maintenance IFX treatment had received 4-48 infusions.IFX trough levels ATI analysed 1-4 times each patient using an in-house ELISA assay.ATI could only be when was undetectable.In total, 93 level tests collected.Demographics, concomitant immunosuppression, CRP, ESR, albumin, the...

10.1093/ecco-jcc/jjw019.640 article EN Journal of Crohn s and Colitis 2016-03-01

Background: Colorectal cancer (CRC) is the third most common and second leading cause of death worldwide with an incidence 10.2%. The treatment CRC has changed over past 25 years. Two surgical procedures are used: abdominoperineal resection (AR) low anterior (LAR) ultra-low (ULAR). recurrence rate quality life similar. Objective: To compare for rectal patients treated vs conservative resections: (ULAR) in UMAE Puebla. Methods: A comparative, observational, cross-sectional study was conducted...

10.25176/rfmh.v23i2.5642 article EN cc-by Revista de la Facultad de Medicina Humana 2023-04-01

ResumenIntroducción: La enfermedad de Parkinson es un trastorno neurodegenerativo progresivo que afecta múltiples sistemas, manifestándose con síntomas motores y no motores.Los urinarios son las manifestaciones motoras más prevalentes.Objetivo: Comparar la calidad vida en pacientes acuerdo su sintomatología urinaria hospital

10.24875/amh.m23000032 article ES cc-by-nc-nd Anales Médicos de la Asociación Médica del Centro Médico ABC 2023-08-30

Antecedentes: La toma de biopsia mamaria es generalmente ambulatoria y se emplean anestésicos locales del grupo amida, cuya combinación poco estudiada.Objetivo: Evaluar la eficacia anestésica lidocaína al 1% más ropivacaína 0.2% en comparación con 2% mamaria.Métodos: Estudio comparativo pacientes programadas para mamaria, aleatorizadas A (ropivacaína + 1%) B (lidocaína 2%).Se evaluó anestesia Escala Verbal Numérica Dolor a los 5 minutos posanestesia 15 30 poscirugía.Se registraron el...

10.24875/amh.m23000039 article ES cc-by-nc-nd Anales Médicos de la Asociación Médica del Centro Médico ABC 2023-11-21

Background: COVID-19 is a disease that since its appearance in 2019 has represented challenge for health services. The sequelae are consequence of deterioration the quality life, fatigue, dyspnea and joint pain. Objective: Compare physical, respiratory, cognitive functional independence parameters post-COVID-19 patients, with respiratory before after physical occupational therapy program. Methods: A comparative, quasi-experimental, prospective study was conducted outpatients discharged from...

10.25176/rfmh.v23i3.5532 article EN cc-by Revista de la Facultad de Medicina Humana 2023-09-14
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