A5073359408- Ear Surgery and Otitis Media
- Infectious Diseases and Tuberculosis
- Noise Effects and Management
- Hearing, Cochlea, Tinnitus, Genetics
- Mycobacterium research and diagnosis
- Tracheal and airway disorders
- Respiratory and Cough-Related Research
- Hearing Impairment and Communication
- Cell Adhesion Molecules Research
- Pediatric health and respiratory diseases
- NF-κB Signaling Pathways
- Respiratory viral infections research
- Cerebral Palsy and Movement Disorders
- Balance, Gait, and Falls Prevention
- Immune Response and Inflammation
- Sinusitis and nasal conditions
- Voice and Speech Disorders
- Congenital Ear and Nasal Anomalies
- Immunodeficiency and Autoimmune Disorders
- Diagnosis and treatment of tuberculosis
- Hearing Loss and Rehabilitation
- Bacterial Infections and Vaccines
- Nasal Surgery and Airway Studies
- Delphi Technique in Research
- Phonocardiography and Auscultation Techniques
University of the Philippines Manila
2007-2023
Philippine General Hospital
2009-2023
Makati Medical Center
2020-2023
Doctors Hospital
2016-2023
University of the Philippines System
2011
National Institutes of Health
2011
Background: Tuberculosis (TB) is a rare cause of otitis media. This study aims to increase awareness on the clinical presentation TB media and illustrate how early detection affects treatment outcome. Methods: Chart review 12 patients (13 ears) from tertiary hospital in Manila, Philippines, seen 2004 2009. Clinical predictors disease were summarized. Clinical, radiologic, audiometric outcomes after compared between groups. Results: The 5 otoscopic presentations multiple perforations, single...
Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and otitis-prone US children. The goal of this study is describe differences the middle ear microbiome between carriers non-carriers duplication variant that increases risk for chronic among Filipinos with poor health care access. Ear swabs obtained from 16 individuals media, whom 11 carry variant. submitted 16S rRNA gene sequencing. Genotype-based microbial richness,...
Background Otitis media (OM) susceptibility has significant heritability; however, the role of rare variants in OM is mostly unknown. Our goal to identify novel that confer susceptibility. Methods We performed exome and Sanger sequencing >1000 DNA samples from 551 multiethnic families with unrelated individuals, RNA-sequencing microbiome analyses swabs outer ear, middle nasopharynx oral cavity. also examined protein localisation gene expression infected healthy ear tissues. Results A...
To analyze the likelihood ratios (LRs) and predictive values of preoperative air-bone gap (ABG) levels on presence gross ossicular discontinuity (OD) among chronic suppurative otitis media (CSOM) patients.Tertiary hospitals.Records 276 patients with CSOM 7 to 75 years old undergoing their first tympanomastoidectomy were reviewed. Association audiogram OD was analyzed using logistic regression analysis chi 2 tests. Frequency-specific ABG compared OD.In without cholesteatoma, 20 dB or less at...
To identify genetic and environmental risk factors for otitis media in an indigenous Filipino population.Cross-sectional study.Indigenous community.Clinical history information on breastfeeding, tobacco smoke exposure, swimming were obtained from community members. Heads of households interviewed family personal beliefs ear health. Height weight measured. Otoscopic findings described the presence character perforation or discharge. An A2ML1 duplication variant that confers susceptibility was...
A genetic basis for otitis media is established, however, the role of rare variants in disease etiology largely unknown. Previously a duplication variant within A2ML1 was identified as significant risk factor an indigenous Filipino population and US children. In this report exome Sanger sequencing performed using DNA samples from population, cochlear implantees, probands, Finnish, Pakistani families with media. Sixteen novel, damaging patients were or low-frequency population-matched...
Objective: To calculate the accuracy, sensitivity, specificity and positive predictive values of Siemens HearCheck™ Navigator in detecting hearing loss to compare these parameters when examination is done a soundproof booth quiet room.
 
 Methods:
 Design: Analytical, cross-sectional study
 Setting: Tertiary Public University Hospital
 Patients: Patients seen at Ear Unit tertiary public university hospital from June 2009 August 2010 were tested using pure tone...
Objective: To determine the prevalence of hearing loss among infants six months old and below sent for newborn screening in our institution, to measure accuracy, sensitivity, specificity positive predictive values reflexive behavioral (“Baah”) test detecting infants.Methods: Design: Cross-sectional study Setting: Ear Unit a tertiary government hospital Participants: Infants less than Six at from April September, 2011 were recruited. All participants tested with OAE screening. was also used...
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Background: Pure tone audiometry is routinely used to determine conductive and sensorineural hearing status. Ossicular discontinuity usually assessed intra-operatively. If ossicular can be predicted by pure audiometry, perhaps the operative procedure of choice prognosis for also anticipated.
 
 Objective: To predictive value preoperative on presence gross in chronic otitis media.
 Methods: Records 205 patients, 7 75 years age undergoing their first operation media were...
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Background: Certain indigenous populations have been noted by the World Health Organization (WHO) to highest prevalence rates for chronic suppurative otitis media (CSOM), including Australian Aborigines (28-43%), Greenlanders (2-10%) and Alaskan Eskimos (2-10%).
 Objectives: To determine of common ear problems, particularly CSOM, among Ati or Aeta community in Bolabog, Boracay, their hearing sensitivity using screening audiometry.
 Methods:
 Study Design: Descriptive...
Background: The Philippine National Ear Institute (PNEI) was created to promote health of hearing and balance among Filipinos. Over the years it, has provided audiologic services thousands patients annually published relevant research.
 Objective: To describe served by PNEI in terms age, region origin, occupation, pretest diagnosis, results.
 Methods: 
 Study Design: Cross-sectional study
 Setting: tertiary care center
 Population: All records referred for testing at...
An abstract is not available for this content. As you have access to content, full HTML content provided on page. A PDF of also in through the ‘Save PDF’ action button.
Background: Many indigenous peoples are at elevated risk for otitis media, however there is limited information on hearing loss due to OM in these communities. An Indigenous Filipino community that has previously been described with an prevalence of rare A2ML1 variants and a common FUT2 variant underwent additional phenological testing. In this study, we describe the audiologic profiles A2ML1- FUT2-related media validity otoscopy genotyping screening loss. Method: We analyzed genotypes...
Objectives. To determine the agreement between 1) ear examination findings of otorhinolaryngologist using an otoscope and trained elementary school nurses a penlight, 2) hearing screening nurses, both Philippine National Ear Institute (PNEI) Method 512 Hz Tuning Fork Test (TFT) 3) PNEI TFT audiometry findings.
 Methods. In this continuing study, residing in venue previously penlight TFT, conducted these children who attended medical mission. Otoscopy, were then on by otolaryngologist....
To determine the initial clinical diagnoses of patients with tuberculous otitis media (TBOM), to value PCR test, biopsy, and ancillary diagnostic procedures in detecting middle ear TB infection, establish differences treatment outcomes.
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Background: The Philippine National Ear Institute (PNEI) was created to promote health of hearing and balance among Filipinos. Over the years it, has provided audiologic services thousands patients annually published relevant research. Objective: To describe served by PNEI in terms age, region origin, occupation, pretest diagnosis, results. Methods: Study Design: Cross-sectional study Setting: tertiary care center Population: All records referred for testing at 2006 were reviewed encoded...