- Fungal Biology and Applications
- Algal biology and biofuel production
- Mycorrhizal Fungi and Plant Interactions
- Polysaccharides and Plant Cell Walls
- Photosynthetic Processes and Mechanisms
- Plant biochemistry and biosynthesis
- Biocrusts and Microbial Ecology
- Medicinal Plants and Bioactive Compounds
- Marine and coastal ecosystems
- Chemical synthesis and alkaloids
- Antioxidant Activity and Oxidative Stress
- Microbial Metabolic Engineering and Bioproduction
- Biodiesel Production and Applications
- Fungal and yeast genetics research
- Microbial Natural Products and Biosynthesis
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Electrocatalysts for Energy Conversion
- Enzyme Catalysis and Immobilization
- Atmospheric and Environmental Gas Dynamics
- Ionic liquids properties and applications
- Advanced Battery Materials and Technologies
- solar cell performance optimization
- Atmospheric chemistry and aerosols
- Allelopathy and phytotoxic interactions
Kunming University of Science and Technology
2016-2025
Shanghai Jiao Tong University
2009-2024
Shanghai First People's Hospital
2021-2024
Peking University
2024
Hunan University
2023-2024
Nantong University
2022
Affiliated Hospital of Nantong University
2022
Weatherford College
2022
University of Chinese Academy of Sciences
2019
Yunnan University of Finance And Economics
2019
Abstract One of the biggest hurdles for development metabolism-targeted therapies is to identify responsive tumor subsets. However, metabolic vulnerabilities most human cancers remain unclear. Establishing link between signatures and oncogenic alterations receptor tyrosine kinases (RTK), well-defined cancer genotypes, may precisely direct intervention a broad patient population. By integrating metabolomics transcriptomics, we herein show that RTK activation causes distinct preference....
Melatonin (MLT), a ubiquitously distributed small molecule, functions in plant responses to various biotic and abiotic stresses. However, the interactions between melatonin other important molecules Haematococcus pluvialis response stresses are largely unknown. In present study, exogenous improved H. resistance nitrogen starvation high light. We concluded that treatment prevented reactive oxygen species (ROS) burst limited cell damage induced by stress through activation of antioxidant...
The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially restoring neuronal functions in brain diseases. However, the functional properties neurons derived from hESC are largely unknown. Moreover, because were under diverse conditions, possibility arises different lines exhibit distinct properties, but this remains unexplored. To address these issues, we developed a protocol allows stepwise...
Ganoderic acids produced by Ganoderma lucidum, a well-known traditional Chinese medicinal mushroom, exhibit antitumor and antimetastasis activities. Genetic modification of G. lucidum is difficult but critical for the enhancement cellular accumulation ganoderic acids. In this study, homologous genetic transformation system was developed first time using mutated sdhB, encoding iron-sulfur protein subunit succinate dehydrogenase, as selection marker. The truncated gene catalytic domain...
Ganoderma lucidum is an important medicinal mushroom in traditional Chinese medicine. However, the lack of adequate genetic tools has hindered molecular research and modification this species. Here, we report that presence intron necessary for efficient expression heterologous phosphinothricin-resistance green fluorescent protein genes G. lucidum. Moreover, improved CRISPR/Cas9-mediated gene disruption frequency by adding upstream Cas9 gene. Our results showed orotidine 5'-monophosphate...