Jun‐Wei Xu

ORCID: 0000-0002-0871-2171
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About
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Research Areas
  • Fungal Biology and Applications
  • Algal biology and biofuel production
  • Mycorrhizal Fungi and Plant Interactions
  • Polysaccharides and Plant Cell Walls
  • Photosynthetic Processes and Mechanisms
  • Plant biochemistry and biosynthesis
  • Biocrusts and Microbial Ecology
  • Medicinal Plants and Bioactive Compounds
  • Marine and coastal ecosystems
  • Chemical synthesis and alkaloids
  • Antioxidant Activity and Oxidative Stress
  • Microbial Metabolic Engineering and Bioproduction
  • Biodiesel Production and Applications
  • Fungal and yeast genetics research
  • Microbial Natural Products and Biosynthesis
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Electrocatalysts for Energy Conversion
  • Enzyme Catalysis and Immobilization
  • Atmospheric and Environmental Gas Dynamics
  • Ionic liquids properties and applications
  • Advanced Battery Materials and Technologies
  • solar cell performance optimization
  • Atmospheric chemistry and aerosols
  • Allelopathy and phytotoxic interactions

Kunming University of Science and Technology
2016-2025

Shanghai Jiao Tong University
2009-2024

Shanghai First People's Hospital
2021-2024

Peking University
2024

Hunan University
2023-2024

Nantong University
2022

Affiliated Hospital of Nantong University
2022

Weatherford College
2022

University of Chinese Academy of Sciences
2019

Yunnan University of Finance And Economics
2019

Abstract One of the biggest hurdles for development metabolism-targeted therapies is to identify responsive tumor subsets. However, metabolic vulnerabilities most human cancers remain unclear. Establishing link between signatures and oncogenic alterations receptor tyrosine kinases (RTK), well-defined cancer genotypes, may precisely direct intervention a broad patient population. By integrating metabolomics transcriptomics, we herein show that RTK activation causes distinct preference....

10.1038/s41467-019-10427-2 article EN cc-by Nature Communications 2019-06-20

Melatonin (MLT), a ubiquitously distributed small molecule, functions in plant responses to various biotic and abiotic stresses. However, the interactions between melatonin other important molecules Haematococcus pluvialis response stresses are largely unknown. In present study, exogenous improved H. resistance nitrogen starvation high light. We concluded that treatment prevented reactive oxygen species (ROS) burst limited cell damage induced by stress through activation of antioxidant...

10.1021/acs.jafc.8b02178 article EN Journal of Agricultural and Food Chemistry 2018-07-05

The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially restoring neuronal functions in brain diseases. However, the functional properties neurons derived from hESC are largely unknown. Moreover, because were under diverse conditions, possibility arises different lines exhibit distinct properties, but this remains unexplored. To address these issues, we developed a protocol allows stepwise...

10.1073/pnas.0706199104 article EN Proceedings of the National Academy of Sciences 2007-08-11

Ganoderic acids produced by Ganoderma lucidum, a well-known traditional Chinese medicinal mushroom, exhibit antitumor and antimetastasis activities. Genetic modification of G. lucidum is difficult but critical for the enhancement cellular accumulation ganoderic acids. In this study, homologous genetic transformation system was developed first time using mutated sdhB, encoding iron-sulfur protein subunit succinate dehydrogenase, as selection marker. The truncated gene catalytic domain...

10.1128/aem.01263-12 article EN Applied and Environmental Microbiology 2012-09-01

Ganoderma lucidum is an important medicinal mushroom in traditional Chinese medicine. However, the lack of adequate genetic tools has hindered molecular research and modification this species. Here, we report that presence intron necessary for efficient expression heterologous phosphinothricin-resistance green fluorescent protein genes G. lucidum. Moreover, improved CRISPR/Cas9-mediated gene disruption frequency by adding upstream Cas9 gene. Our results showed orotidine 5'-monophosphate...

10.1111/1751-7915.13534 article EN cc-by Microbial Biotechnology 2020-01-20
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