A5025545649- Curcumin's Biomedical Applications
- Clinical Nutrition and Gastroenterology
- Tea Polyphenols and Effects
- Phytochemicals and Antioxidant Activities
- Nanoparticle-Based Drug Delivery
- Pharmaceutical studies and practices
- Nanoplatforms for cancer theranostics
- Antibiotics Pharmacokinetics and Efficacy
- Salivary Gland Tumors Diagnosis and Treatment
- Ginkgo biloba and Cashew Applications
- Pharmacological Effects and Toxicity Studies
- Surgical Simulation and Training
- Electrolyte and hormonal disorders
- Digital Imaging in Medicine
- RNA Interference and Gene Delivery
- Retinoids in leukemia and cellular processes
- Glioma Diagnosis and Treatment
- Diet and metabolism studies
Poznan University of Medical Sciences
2020-2024
Nanoformulations are regarded as a promising tool to enable the efficient delivery of active pharmaceutical ingredients target site. One best-known and most studied nanoformulations liposomes-spherical phospholipid bilayered nanocarriers resembling cell membranes. In order assess possible effect mixture polyphenols on both stability formulation its biological activity, two compounds were embedded in liposomes-(i) curcumin (CUR), (ii) peracetylated derivative (-)-epigallocatechin 3-O-gallate...
Glioblastoma (GBM) is the most common malignant neoplasm in adults among all CNS gliomas, with 5-year survival rate being as low 5%. Among nanocarriers, liposomal nanoformulations are considered a promising tool for precise drug delivery. The herein presented study demonstrates possibility of encapsulating four selected natural compounds (curcumin, bisdemethoxycurcumin, acteoside, and orientin) their mixtures cationic nanoformulation composed two lipid types (DOTAP:POPC). In order to...
Epilepsy is defined as a group of concerning problems related to the nervous system; its defining feature predisposition epileptic seizures. The frequency seizures in intensive care units (ICU) ranges from 3.3% 34%, and ICU antiepileptic treatment routine practice. administration drugs through same infusion line not recommended but common clinical practice, especially ICU. Incompatibilities between parenteral nutrition admixtures (PNAs) are medical errors pose risks patient safety....
Vinpocetine (VP) is distributed after oral and intravenous administration, its uptake in the thalamus, basal ganglia, visual cortex. Due to poor bioavailability (~7%) marked first-pass effect (~75%), including a short half-life (2-3 h), administration of VP limited. It requires frequent drug obtain therapeutic effect. Attempts overcome these difficulties include use new delivery systems and/or alternative routes administration. One possibility common lipid emulsion using same catheter....
Simultaneous administration of parenteral nutrition (PN) admixtures with intravenous antibiotics is a common clinical problem. Coadministration drugs incompatible PN admixture may affect its stability, especially in the context lipid droplet size, which crucial parameter for patient safety. In present study, we investigate vitro compatibility meropenem (Meropenem 1000, MPM) five commercial used worldwide: Kabiven, Olimel N9E, Nutriflex Lipid Special, Omega and SmofKabiven. The appropriate...
To develop a comprehensive operative report schema based on the accuracy of primary reports (OpR) assessed department's experience with parotid gland tumor re-operations.Retrospective cross-sectional study.A tertiary referral center, Department Otolaryngology and Laryngological Surgery, Poznan University Medical Sciences, Poland from 2008 to 2017.Out 1154 surgeries, 71 patients underwent reoperation. Their OpR were categorized into accurate non-accurate, re-operation field course as...