A5102721921- Organic Electronics and Photovoltaics
- Particle physics theoretical and experimental studies
- Conducting polymers and applications
- Cancer-related molecular mechanisms research
- High-Energy Particle Collisions Research
- RNA modifications and cancer
- Particle Detector Development and Performance
- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Air Quality and Health Impacts
- Asthma and respiratory diseases
- Heme Oxygenase-1 and Carbon Monoxide
- Fungal Biology and Applications
- Genomics, phytochemicals, and oxidative stress
- Building Energy and Comfort Optimization
- Quantum Chromodynamics and Particle Interactions
- Cancer-related gene regulation
- Power System Optimization and Stability
- PI3K/AKT/mTOR signaling in cancer
- Plant-derived Lignans Synthesis and Bioactivity
- Ubiquitin and proteasome pathways
- Respiratory and Cough-Related Research
State Key Laboratory of Respiratory Disease
2025
Second Affiliated Hospital of Guangzhou Medical University
2025
Guangzhou Medical University
2025
Capital Medical University
2015-2024
Sichuan University
2023-2024
State Key Laboratory of Biotherapy
2024
Beijing Jishuitan Hospital
2024
Peking University
2024
Beijing Obstetrics and Gynecology Hospital
2023-2024
Anhui Normal University
2023
Plate-like heterogeneous NiO/WO₃ nanocomposites have been successfully prepared by annealing Ni(OH)₂ and H₂WO₄ in air. These shown excellent sensitivity towards NO₂ ultrafast response at room temperature due to their p-n characteristics.
Eliminating the excess energetic driving force in organic solar cells leads to a smaller energy loss and higher device performance; hence, it is vital understand relation between interfacial energetics photoelectric conversion efficiency. In this study, we systematically investigate 16 combinations of four donor polymers acceptors planar heterojunction. The charge generation efficiency its electric field dependence correlate with difference singlet excited state transfer state. threshold 0.2...
Abstract Increasing evidence suggested that benzene exposure resulted in different types of hematological cancer. Both autophagy and apoptosis were reported to play vital roles toxicity, but the relationship between remain unclear benzene-induced hematotoxicity. In this study, toxic effect on benzene-exposed workers vitro verified. Results showed metabolite (1, 4-benzoquinone, 1, 4-BQ) dose-dependently induced via enhancing phosphorylation Bcl-2 beclin1. Finally, we also found elevated ROS...
A centralized forecasting method is difficult to accurately follow load variation and weather diversity throughout the region in a bulk power system that covers large geographical area. distributed based on local information proposed this paper. First, partitioned into some subnets information. Second, separate models are established for subnets. These selected from model base, which includes neural network, autoregressive integrated moving average model, average, gray so on. Cosine distance...
GPR34 is a functional G-protein-coupled receptor of Lysophosphatidylserine (LysoPS), and has pathogenic roles in numerous diseases, yet remains poorly targeted. We herein report cryo-electron microscopy (cryo-EM) structure bound with LysoPS (18:1) G i protein, revealing unique ligand recognition mode the negatively charged head group occupying polar cavity formed by TM3, 6 7, hydrophobic tail residing lateral open groove TM3-5. Virtual screening subsequent structural optimization led to...
During the formation of endosomal pathway-dependent extracellular vesicles (EVs), intraluminal in multivesicular bodies (MVBs) fuse with plasma membrane (PM), releasing to produce exosomes. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, fusion effector, is essential this process. However, which SNARE complex involved MVB and PM how its assembly regulated remain elusive. We have demonstrated that neddylation Coro1a inhibits EV secretion by inducing...
Abstract The secret to the success of mixed bulk heterojunctions (BHJs) in yielding highly efficient organic solar cells (OSCs) could reside molecular structures at their donor/acceptor (D/A) interfaces. In this study, we aimed determine effects energy and charge cascade interfaces by using well-defined planar (PHJs) as a model system. results showed that (1) structure enhanced V OC because it shuts down recombination pathway through transfer (CT) state with low energy, (2) layer having...
Metabolomics has been used to explore the molecular mechanism and screen biomarkers. However, critical metabolic signatures associated with benzene-induced hematotoxicity remain elusive. Here, we performed a plasma metabolomics study in 86 benzene-exposed workers 76 healthy controls, followed by validation analysis mice, investigate dynamical change of profile. We found that 8 fatty acids were significantly altered both worker animal models. These metabolites S-phenylmercapturic acid WBC,...
Long term low-dose benzene exposure leads to the inhibition of haematopoiesis. However, underlying mechanisms remained poorly defined, especially mediated by early effector molecules.Here, we first found in mRNA microarray that pyroptotic classic genes (Casp1, 4, 5, and IL1β) were up-regulated represented dose-dependent differential expression controls, benzene-exposed chronic benzene-poisoned workers, Casp1 IL1β confirmed workers was accompanied with elevated potent proinflammatory IL1β. In...
A good-performance and low-cost electrocatalyst Ni–rGO/CeO 2 has been achieved due to the increased oxygen vacancies active sites brought about by synergistic effect of rGO decoration Ni doping.
Abstract: Given the tremendous growth in application of titanium dioxide nanoparticles (TNPs), concerns about potential health hazards TNPs to humans have been raised. Poly(ADP-ribose) polymerase 1 (PARP-1), a highly conserved DNA-binding protein, is involved many molecular and cellular processes. Limited data demonstrated that certain nanomaterials induced aberrant hypermethylation PARP-1. However, mechanism TNP-induced PARP-1 abnormal methylation has not studied. A549 cells were incubated...
Cryptococcus neoformans ( C. )/ gattii can easily invade the human central nervous system and cause cryptococcal meningitis (CM). The clinical fatality rate of these fungi is extremely high causes more than 180,000 deaths worldwide every year. At present, common identification methods are traditional culture Indian ink staining. In addition, enzyme-linked immunosorbent assay (ELISAs), polymerase chain reaction (PCR), real-time quantitative PCR detecting (qPCR), mass spectrometry, metagenomic...