A5089235861- Advanced Photocatalysis Techniques
- Plant Gene Expression Analysis
- Advanced Radiotherapy Techniques
- Plant biochemistry and biosynthesis
- Photosynthetic Processes and Mechanisms
- Solar-Powered Water Purification Methods
- Heat and Mass Transfer in Porous Media
- Surface Chemistry and Catalysis
- Covalent Organic Framework Applications
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
- Radiative Heat Transfer Studies
- Plant Stress Responses and Tolerance
- Thermochemical Biomass Conversion Processes
- Phytochemicals and Antioxidant Activities
- Diagnosis and Treatment of Venous Diseases
- Piezoelectric Actuators and Control
- Evaluation and Optimization Models
- Medical Imaging Techniques and Applications
- Medical Imaging and Analysis
- Advanced biosensing and bioanalysis techniques
- Nanopore and Nanochannel Transport Studies
- Biosensors and Analytical Detection
- Immune Cell Function and Interaction
- Electrocatalysts for Energy Conversion
Southern Medical University
2020-2025
University of Michigan
2020-2024
University of Florida
2024
Beijing University of Chinese Medicine
2024
Qingdao University
2023-2024
Yangzhou University
2022-2024
University of South China
2023-2024
National Synchrotron Radiation Laboratory
2023
Guangzhou University
2020-2023
University of Science and Technology of China
2023
Abstract Metabolic regulation has been proven to play a critical role in T cell antitumor immunity. However, cholesterol metabolism as key component of this remains largely unexplored. Herein, we found that the low-density lipoprotein receptor (LDLR), which previously identified transporter for cholesterol, plays pivotal regulating CD8 + activity. Besides involvement uptake is mediated by LDLR priming and clonal expansion, also non-canonical function cells: interacts with T-cell (TCR)...
SUMMARY Drought is a detrimental environmental factor that restricts plant growth and threatens food security throughout the world. WRKY transcription factors play vital roles in abiotic stress response. However, of IIe subgroup members from family soluble sugar mediated drought response are largely elusive. In this study, we identified drought‐responsive factor, PoWRKY69, Paeonia ostii . PoWRKY69 functioned as positive regulator to with nucleus expression transcriptional activation...
Our previous study has proved that the three polysaccharide fractions from L. japonica (LP-A4, LP-A6, and LP-A8) had significantly different structure characterization. Herein, we conducted in vitro simulated digestion fermentation to digestive mechanism of LP-As. The results gastrointestinal indicated LP-A6 LP-A8 would be easier trap enzyme molecules for their denser interconnected macromolecule network compared with LP-A4. Fermentation LP-As by human gut microbiota, especially LP-A8,...
Abstract The electrical and mechanical properties of graphene‐based materials can be tuned by the introduction nanopores, which are sensitively related to size, morphology, density, location nanopores. synthesis low‐dimensional graphene nanostructures containing well‐defined nonplanar nanopores has been challenging due intrinsic steric hindrance. Herein, we report selective one‐dimensional (1D) nanoribbons (GNRs) periodic [14]annulene pores on Ag(111) two‐dimensional (2D) porous nanosheet...
Flexible grippers with superior gripping capabilities are essential for carrying objects. Herein, an origami chomper‐based flexible gripper is designed using a combination of the technique and newly developed nonlinear topology optimization method. This novel exhibits performance, as revealed by series experiments, including range capability under identical input load, maximum ratio, adaptability, achieving richer characteristics size scaling. The can handle wide object irregularities in...
Although the functions of WRKY transcription factors in drought resistance are well known, their regulatory mechanisms response to by stabilising photosynthesis remain unclear. Here, a differentially expressed PoWRKY71 gene that was highly drought-treated Paeonia ostii leaves identified through transcriptome analysis. positively responded stress with significantly enhanced expression patterns and overexpressing tobacco greatly improved plant tolerance stress, whereas silencing P. resulted...
Objective.To establish an open framework for developing plan optimization models knowledge-based planning (KBP).Approach.Our includes radiotherapy treatment data (i.e. reference plans) 100 patients with head-and-neck cancer who were treated intensity-modulated radiotherapy. That also high-quality dose predictions from 19 KBP that developed by different research groups using out-of-sample during the OpenKBP Grand Challenge. The input to four fluence-based mimicking form 76 unique pipelines...
Abstract Nutrient metabolisms are vitally interrelated to cancer progression and immunotherapy. However, the mechanisms by which nutrient interact remodel immune surveillance within tumor microenvironment remain largely unexplored. Here it is demonstrated that methionine restriction inhibits expression of proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator cholesterol homeostasis potential target for immunotherapy, in colorectal (CRC) but not liver. Mechanistically,...
The tree peony (Paeonia suffruticosa Andr.) has been widely cultivated as a field plant, and petal blotch is one of its important traits, which not only promotes proliferation but also confers high ornamental value. However, the regulatory network controlling formation remains elusive owing to functional differences limited conservation transcriptional regulators in dicots.We performed phylogenetic analysis identify MYB44-like transcription factors P. blotched cultivar 'High noon' petals. A...
The Kagome lattice structures based on metal–organic coordination have garnered widespread interest because of their topologically Dirac/flat bands and other exotic electronic structures. However, the experimental fabrication large-area two-dimensional (2D) frameworks (MOFs) via on-surface synthesis remains limited. Herein, we successfully construct two kinds large-scale 2D Kagome-type lattices stabilized by 4-fold N–Ag Ag(111) surface. With aid scanning tunneling microscopy (STM)...
Abstract Objective This paper intends to propose a method of using TransResSEUnet2.5D network for accurate automatic segmentation the Gross Target Volume (GTV) in Radiotherapy lung cancer. Methods A total 11,370 computed tomograms (CT), deriving from 137 cases, cancer patients under radiotherapy developed by radiotherapists were used as training set; 1642 CT images 20 cases validation set, and 1685 test set. The proposed was tuned trained obtain best model its performance measured Dice...
With persistent elevation in global temperature, water scarcity becomes a major threat to plant growth and development, yield security, agricultural sustainability, food production. Proline, as key osmolyte antioxidant, plays critical role regulating drought tolerance plants, especially its biosynthetic enzyme, delta-1-pyrroline-5-carboxylate synthase (P5CS), which always positively responds stress. As an important woody oil crop, the expansion of
The herbaceous peony (Paeonia lactiflora Pall.) is widely cultivated as an ornamental, medicinal and edible plant in China. Drought stress can seriously affect the growth of reduce its quality. In our previous research, a significantly differentially expressed gene, PM19L, was obtained under drought based on transcriptome analysis, but little known about function. this study, first PM19L that isolated comprised 910 bp, designated PlPM19L (OP480984). It had complete open reading frame 537 bp...
During the coronavirus disease 2019 pandemic, we considered case of a child with developmental language disorder (DLD) who could not go to hospital on time receive timely rehabilitation treatment due disrupted operations. The application cloud-based platforms has provided significant advantages and convenience for children DLD in-home remote rehabilitation. Among them, JingYun Rehab Cloud Platform is most widely used in mainland China. It an interactive telerehabilitation system developed by...
ATP-citrate lyase (ACL) gene catalyzes the formation of acetyl-CoA to provide intermediate precursors for many secondary metabolites, and also plays an important role in anthocyanin biosynthesis plants. Herbaceous peony (Paeonia lactiflora Pall.) is international cut flower known its rich colors, however, function ACL color regulation still unclear. Here, double-colored P. 'Hebao Jinlian' were used study molecular mechanism red petal, related PlACLB2, PlCHS, PlDFR, PlANS, PlbHLH1 genes...
SnSe is a potential thermoelectric material, but there are few reports about the properties of film. In this work, thin films were deposited on glass substrates by RF magnetron sputtering from alloy target. The effect substrate temperature structural and was investigated. It found that columnar grains surface roughness increase with increasing temperature. film at 558 K exhibited high crystalline quality stoichiometric composition, which has maximum power factor 1.4[Formula: see...