A5005026556- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Cleft Lip and Palate Research
- Intestinal Malrotation and Obstruction Disorders
- Anatomy and Medical Technology
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Craniofacial Disorders and Treatments
- Oral microbiology and periodontitis research
- Additive Manufacturing and 3D Printing Technologies
- Reconstructive Surgery and Microvascular Techniques
- Dental materials and restorations
- Congenital Anomalies and Fetal Surgery
- Traumatic Ocular and Foreign Body Injuries
- Surface Modification and Superhydrophobicity
- Gastrointestinal disorders and treatments
- Intestinal and Peritoneal Adhesions
- Neurological Complications and Syndromes
- Congenital gastrointestinal and neural anomalies
- Tissue Engineering and Regenerative Medicine
- Plasma Applications and Diagnostics
- Head and Neck Cancer Studies
- Orthopedic Surgery and Rehabilitation
- Muscle and Compartmental Disorders
University of Miami
2018-2025
This manuscript reviews the transformative impact of 3-dimensional (3D) printing technologies in treatment and management cleft lip palate (CLP), highlighting its application across presurgical planning, surgical training, implantable scaffolds, postoperative care. By integrating patient-specific data through computer-aided design manufacturing, 3D offers tailored solutions that improve outcomes, reduce operation times, enhance patient The review synthesizes current research findings,...
ABSTRACT This preclinical, in vivo study aimed to histologically and histomorphometrically evaluate the effect of implant design features on bone healing during early stages osseointegration. Three different macrogeometries surface treatments were evaluated: (1) trapezoidal threads with decompressing vertical chambers blasted acid‐etched (Maestro/Blasted+AE); (2) large thread pitch deep wide threads, TiUnite (RS/TiUnite); (3) progressive buttress SLActive (BL/SLActive). Implant surfaces...
Bone tissue regeneration is a complex process that proceeds along the well-established wound healing pathway of hemostasis, inflammation, proliferation, and remodeling. Recently, engineering efforts have focused on application biological technological principles for development soft hard substitutes. Aim directed towards boosting pathways to restore form function deficits. Continued synthetic scaffolds, cell therapies, signaling biomolecules seeks minimize need autografting. Despite being...
To develop a peri-implantitis model in Gottingen minipig and evaluate the effect of local application salicylic acid poly(anhydride-ester) (SAPAE) on progression healthy, metabolic syndrome (MS), type-2 diabetes mellitus (T2DM) subjects. Eighteen animals were allocated to three groups: (i) control, (ii) MS (diet for obesity induction), (iii) T2DM plus streptozotocin induction). Maxillary mandible premolars first molar extracted. After 3 months healing, four implants per side placed both jaws...
Abstract Federal government research grants provide limited funding to plastic surgeon-scientists, with reconstructive taking precedence over aesthetic research. The Aesthetic Surgery Education and Research Foundation (ASERF) is a nonprofit, 501(c)(3) organization that seeks support innovative, diverse endeavors within surgery. A total of 130 ASERF-funded studies 32 non-funded applications from 1992 2022 were reviewed. Kruskal Wallis, Fisher's exact, chi-squared tests utilized assess the...
Non-union during healing of bone fractures affects up to ~5% patients worldwide. Given the success recombinant human platelet-derived growth factor-B chain homodimer (rhPDGF-BB) in promoting angiogenesis and fusion hindfoot ankle, rhPDGF-BB combined with bovine type I collagen/β-TCP matrix (AIBG) could serve as a viable alternative autografts treatment non-unions. Defects (~2 mm gaps) were surgically induced tibiae skeletally mature New Zealand white rabbits. Animals allocated one four...
Non-resorbable dental barrier membranes entail the risk of dehiscence due to their smooth and functionally inert surfaces. Non-thermal plasma (NTP) treatment has been shown increase hydrophilicity a biomaterials could thereby enhance cellular adhesion. This study aimed elucidate role allyl alcohol NTP poly(tetrafluoroethylene) in its The materials (non-treated PTFE (NTMem) NTP-treated (PTMem)) were subjected characterization using scanning electron microscopy (SEM), contact angle...
Abstract To evaluate the cellular response of both an intact fish skin membrane and a porcine‐derived collagen investigate bone healing these membranes using translational, preclinical, guided‐bone regeneration (GBR) canine model. Two different naturally sourced were evaluated in this study: (i) (Kerecis Oral®, Kerecis) (ii) porcine derived (Mucograft®, Geistlich) membrane, positive control. For vitro experiments, human osteoprogenitor (hOP) cells used to assess viability proliferation at...
Computer-aided design/computer-aided manufacturing and 3-dimensional (3D) printing techniques have revolutionized the approach to bone tissue engineering for repair of craniomaxillofacial skeletal defects. Ample research has been performed gain a fundamental understanding optimal 3D-printed scaffold design composition facilitate appropriate formation healing. Benchtop preclinical, small animal model testing bioactive ceramic scaffolds augmented with pharmacological/biological agents yielded...
Background: There are few nationwide studies comparing outcomes of open, laparoscopic (LAP), and percutaneous endoscopic (PEG) gastrostomy tube (GT) placement in the pediatric population. Materials Methods: The Nationwide Readmissions Database from 2010 to 2014 was used identify patients ≤18 years (excluding newborns) who underwent GT placement. Demographics, hospital characteristics, were compared by approach. Results: 3278 (41% female, age 3 ± 5 years) identified (40% open versus 32% PEG...
Abstract Periodontitis is a bacteria‐induced chronic inflammatory disease characterized by degradation of the supporting tissue and bone in oral cavity. Treatment modalities seek to facilitate periodontal rehabilitation while simultaneously preventing further gingival recession potentially atrophy. The aim this study was compare two differently sourced membranes, resorbable piscine collagen membrane porcine‐derived membrane, repair soft defects utilizing preclinical canine model. This vivo...
BACKGROUND: β-tricalcium phosphate (β-TCP) has been successfully utilized as a 3D printed ceramic scaffold in the repair of non-healing bone defects; however, it requires addition growth factors to augment its regenerative capacity. Synthetic mineral (SBM) is novel and extrudable carbonate hydroxyapatite with ionic substitutions known facilitate healing. However, efficacy for hard tissue defect not explored. OBJECTIVE: To evaluate biocompatibility cell viability human osteoprecursor (hOP)...
Purpose: Defects arising from craniofacial anomalies, trauma, or tumor resection often require soft tissue reconstruction with grafting. While autologous pedicle free palatal grafts remain the gold standard, numerous xenografts serve as possible alternatives. Existing literature on use of porcine derived collagen membranes (PDCM) for intraoral regeneration has reported favorable outcomes increasing keratinized width. However, strategies to improve regenerative capacity PDCMs under continuous...
Definitive oronasal separation through closure of the velopharyngeal (VP) sphincter is necessary for development normal speech and feeding. Individuals with incompetence or insufficiency often exhibit hypernasal speech, poor intelligibility, nasal regurgitation. Assessment VP function using nasopharyngoscopy a key element in identifying dysfunction. A foundational understanding anatomy physiology mechanism paramount to successful diagnosis. This includes recognition 4 distinct patterns:...
Summary: Finger entrapment with rings or ring-like objects is an uncommon possible hand emergency. In cases in which noncutting removal ineffective, ring cutters dental drills carbide diamond burs have been successfully used. However, composed of hard metallic alloys, such as lug nuts wrenches, are often resistant to equipment. these instances, larger diameter metal cutting burrs rasps may be more advantageous. Due their increased size and power, tools better suited handle the toughness...