A5089968015- Radical Photochemical Reactions
- Biochemical Analysis and Sensing Techniques
- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Plant Gene Expression Analysis
- RNA and protein synthesis mechanisms
- Sulfur-Based Synthesis Techniques
- Nanoplatforms for cancer theranostics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Agriculture Sustainability and Environmental Impact
- bioluminescence and chemiluminescence research
- Photodynamic Therapy Research Studies
- Advanced Photocatalysis Techniques
- Photochromic and Fluorescence Chemistry
- Click Chemistry and Applications
- Microbial Metabolites in Food Biotechnology
- Microbial Natural Products and Biosynthesis
- Transgenic Plants and Applications
- Meat and Animal Product Quality
- Metal-Catalyzed Oxygenation Mechanisms
- Enzyme-mediated dye degradation
- Fermentation and Sensory Analysis
Jiangnan University
2019-2024
Henan Agricultural University
2023
Wuxi Institute of Technology
2019
Cercosporin was developed as a green and efficient organophotocatalyst for wide range of selective oxidations with reactive oxygen species.
Owing to zero-calorie and advanced organoleptic properties similar sucrose, the plant-derived rebaudioside M (Reb M) has been considered as a next generation sweetener. However, low content of Reb in Stevia rebaudiana Bertoni enzymatic activity UGT76G1, which is an uridine diphosphate glucose (UDPG)-dependent glycosyltransferase with ability glycosylate D D) produce through formation β-1,3 glycosidic bond, restrict its commercial usage. To improve catalytic variant UGT76G1-T284S/M88L/L200A...
Sunlight along with cercosporin, produced by a new endophytic fungus, catalyzes the direct arylation of (het)arenes photoredox process.
Abstract The construction of structural complexity and diversity natural products is crucial for drug discovery development. To overcome high dark toxicity poor photostability photosensitizer perylenequinones (PQs) photodynamic therapy, herein, we aim to introduce the biosynthesize desired unnatural PQs in fungus Cercospora through synthetic biology‐based strategy. Thus, first elucidate intricate biosynthetic pathways class B reveal how branching enzymes create their from a common ancestor....
Methylenedioxy bridges (MDBs) are architecturally important motifs in natural products and bioactive molecules. Cercosporin, a typical perylenequinone pigment, contains an unusual seven-membered MDB, which has versatile biological photocatalytic activities. Although cercosporin been isolated, characterized, studied for several decades, its biosynthetic pathway, especially the formation of remained unclear. Here, we show that MDB is catalyzed by Fe(II)/α-ketoglutaric acid (α-KG)-dependent...
Owing to zero-calorie, high-intensity sweetness and good taste profile, the plant-derived sweetener rebaudioside D (Reb D) has attracted great interest replace sugars. However, low content of Reb in stevia rebaudiana Bertoni as well soluble expression enzymatic activity glycosyltransferase preparation restrict its commercial usage. To address these problems, a novel YojK from Bacillus subtilis 168 with ability glycosylate A produce was identified. Then, structure-guided engineering performed...
Abstract The construction of structural complexity and diversity natural products is crucial for drug discovery development. To overcome high dark toxicity poor photostability photosensitizer perylenequinones (PQs) photodynamic therapy, herein, we aim to introduce the biosynthesize desired unnatural PQs in fungus Cercospora through synthetic biology‐based strategy. Thus, first elucidate intricate biosynthetic pathways class B reveal how branching enzymes create their from a common ancestor....
Plant-based meat analogues offer an environmentally and scientifically sustainable option as a substitute for animal-derived meat. They contribute to reducing greenhouse gas emissions, freshwater consumption, the potential risks associated with zoonotic diseases linked livestock production. However, specific processing methods such extrusion or cooking, using various raw materials, can influence survival growth of spoilage pathogenic microorganisms, resulting in differences between...