A5015812270- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Sulfur-Based Synthesis Techniques
- Metal-Organic Frameworks: Synthesis and Applications
- X-ray Diffraction in Crystallography
- Polymer Nanocomposites and Properties
- Crystallization and Solubility Studies
- Asphalt Pavement Performance Evaluation
- Synthesis and Catalytic Reactions
- Luminescence and Fluorescent Materials
- Covalent Organic Framework Applications
- Asymmetric Hydrogenation and Catalysis
- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Fluorine in Organic Chemistry
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Molecular Sensors and Ion Detection
- Innovative concrete reinforcement materials
- Analytical Chemistry and Sensors
- Radical Photochemical Reactions
- Catalysis for Biomass Conversion
- Cyclopropane Reaction Mechanisms
- Nanoplatforms for cancer theranostics
- Metal complexes synthesis and properties
Guangdong Academy of Sciences
2016-2025
Hebei University
2020-2024
Shandong University of Technology
2024
Nankai University
2024
Nanjing Agricultural University
2017-2022
Anhui University
2019-2022
Guangxi University
2018-2021
Yangzhou University
2021
Zhangzhou Vocational and Technical College
2019-2020
Huzhou Vocational and Technical College
2019-2020
The recent advances in photochemical or electrochemical C–F bond activation and functionalization have been summarized discussed.
A new stepwise ligand-elongation strategy by amide spacers is utilized to prepare isoreticularly high-porous metal-organic frameworks (MOFs), namely, quasi-mesoporous [Cu2 (PDBAD)(H2 O)]n (H4 PDBAD=5,5'-((4,4'-((pyridine-3,5-dicarbonyl)bis(azanediyl))bis(benzoyl))bis(azanediyl))diisophthalic acid; NJU-Bai22: NJU-Bai for Nanjing University Bai's group), and mesoporous (PABAD)(H2 PABAD=5,5'-((4,4'-((4,4'-((pyridine-3,5-dicarbonyl)bis(azanediyl))bis(benzoyl))bis...
Bacteria-infected skin wounds caused by external injuries remain a serious challenge to the whole society. Wound healing dressings, with excellent antibacterial activities and potent regeneration capability, are increasingly needed clinically. Here, we reported novel functional microneedle (MN) array comprising methacrylated hyaluronic acid (MeHA) embedded pH-responsive functionalized zeolitic imidazolate framework-8 (ZIF-8) nanoparticles treat bacteria-infected cutaneous wounds....
Owing to zero-calorie and advanced organoleptic properties similar sucrose, the plant-derived rebaudioside M (Reb M) has been considered as a next generation sweetener. However, low content of Reb in Stevia rebaudiana Bertoni enzymatic activity UGT76G1, which is an uridine diphosphate glucose (UDPG)-dependent glycosyltransferase with ability glycosylate D D) produce through formation β-1,3 glycosidic bond, restrict its commercial usage. To improve catalytic variant UGT76G1-T284S/M88L/L200A...
Functionalization of Si-bound methyl group provides an efficient access to diverse organosilanes. However, the asymmetric construction silicon-stereogenic architectures by functionalization has not yet been described despite recent significant progress in producing chiral silicon. Herein, we disclosed enantioselective silylmethyl involving aryl alkyl 1,5-palladium migration naphthalenes possessing enantioenriched stereogenic silicon center, which are inaccessible before. It is worthy note...
ABSTRACT Graphene nanoparticles (GNPs) added styrene‐butadiene‐styrene (SBS)‐modified asphalt suffers from serious compatibility and agglomeration problems. To tackle these problems, in this study, graphene oxide (GO) was mixed with bromobutane to synthesize butylated (C 4 H 9 ‐GO) composite, which turn compounded SBS for the preparation of C ‐GO/SBS‐modified asphalt. ‐GO/SBS‐1.0‐modified exhibited best performance terms 11.4% increased softening point, 19.3% ductility, 10.2% reduction...
Abstract Square planar Pt(II) complexes are promising candidates for use as luminophores in organic light‐emitting diodes (OLEDs). Recently, Wang et al. reported their findings on that incorporate 4‐phenyl‐1,2,3‐triazole with various linker groups (O, CH 2 , C═O). These compounds exhibit different spectral characteristics and distinct quantum yields (Φp). In this work, a theoretical investigation of related is presented utilizing density functional theory (DFT) time‐dependent DFT (TD‐DFT)...
A new series of phosphodiesterase-9 (PDE9) inhibitors that contain a scaffold 6-amino-pyrazolopyrimidinone have been discovered by combination structure-based design and computational docking. This procedure significantly saved the load chemical synthesis is an effective method for discovery inhibitors. The best compound 28 has IC(50) 21 nM 3.3 μM, respectively, PDE9 PDE5 about 3 orders magnitude selectivity against other PDE families. crystal structure catalytic domain in complex with...
Abstract A mild and highly efficient Cu‐catalyzed cascade cyclization/thiocyanation of unactivated alkenes bearing hydrazones has been developed. broad range SCN‐substituted pyrazolines have readily obtained in good to excellent yields with commercially available very cheap Cu(acac) 2 NH 4 SCN. This present method provides a rapid, facile, practical access valuable the important SCN functionality, it is amenable gram scale. magnified image
Abstract Oxidative radical cascade spirocyclization and dearomatization of biary ynones with a variety hydrocarbons including toluenes, ethers, ketones, alkanes has been developed to construct alkyl substituted spiro[5.5]trienones.
Abstract Pyrrole‐2‐carbohydrazides were synthesized and found to be novel efficient ligands for the Cu‐catalyzed amination of aryl halides with amines in pure water high yields. A variety bromides or iodides could aminated, promoted by CuI/ N′ ‐phenyl‐1 H ‐pyrrole‐2‐carbohydrazide ( L13 ) system, under microwave irradiation conventional heating without protection an inert gas.
Abstract The N 2 ,N ′ ‐diisopropyloxalohydrazide/CuO system efficiently catalyzed the direct amination of aryl bromides andiodides with aqueous ammonia in water at 60 °C 24 h or 120 only 20–30 min. Both activated and unactivated heteroaryl iodides were readily aminated good to excellent yields.
In this work, we employed a new tetrazolyl-functionalized ligand, 5-(1H-tetrazole-5-yl)-1,3-bis(3,5-dicarboxylphenyl)-benzene (H5TBDPB), and successfully obtained an example of incorporating free tetrazolyl groups in transition-metal-based MOFs based upon ideal MOF platform. With BET surface area 2070 m2 g-1, tetrazolyl-decorated [Cu6(TBDPB)3(H2O)6]·9DMF·15H2O (HHU-5, HHU for Hohai University) exhibits high CO2 adsorption capacity 37.1 wt % at 1 bar 273 K separation toward N2 CH4 as well.
Through a covalent grafting reaction, octadecyl amine (ODA) was grafted on the surface of waste rubber powder (WRP) to obtain an ODA-WRP modifier, which in turn compounded with styrene-butadiene-styrene block copolymer (SBS) prepare ODA-WRP/SBS-modified asphalt. The three major indicators (i.e., dynamic shear rheometer (DSR), multi-stress creep recovery (MSCR), and separation tests) showed that 1-ODA-WRP effectively improved complex modulus (G*), elastic Modulus (G'), loss (G″) by 36.47%,...
Separation and detection of proteins have been realized on nonionic surfactant-modified poly(dimethylsiloxane) (PDMS) microfabricated devices with end-column amperometric detection. The hydrophobic PDMS channels are turned into hydrophilic ones after being modified Brij35 facilitate the separation proteins. coating can remarkably reduce adsorption large protein molecules is stable in range pH 6-12. such needs less rinsing time thus efficiency raised. Even also be detected better...
A highly efficient copper-catalyzed cyclization/cyanation cascade of unactivated olefins bearing oximes is described. variety cyano-containing isoxazolines have been obtained in high yields with cheap Cu(NO3)2·3H2O as the catalyst and TMSCN non-metallic cyanide source. The present method provides a mild, simple, practical access to cyano-substituted amenable gram scale. simultaneous construction C(sp3)–CN C–O bonds can be achieved one step.
Copper-based MOF-199 was used as an efficient heterogeneous catalyst to catalyze cross-coupling reactions between <italic>N</italic>-containing heterocycles and aryliodides with high yields.