- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Dementia and Cognitive Impairment Research
- Sepsis Diagnosis and Treatment
- Mental Health and Psychiatry
- Respiratory Support and Mechanisms
- Impact of AI and Big Data on Business and Society
- Color perception and design
- Olfactory and Sensory Function Studies
- Intensive Care Unit Cognitive Disorders
- Schizophrenia research and treatment
- Shoulder Injury and Treatment
- Social Policies and Family
- Hemodynamic Monitoring and Therapy
- Sleep and Work-Related Fatigue
- Psychosomatic Disorders and Their Treatments
- Health, psychology, and well-being
- Neurology and Historical Studies
- Pain Management and Placebo Effect
- Hospital Admissions and Outcomes
- Attention Deficit Hyperactivity Disorder
- Cardiac, Anesthesia and Surgical Outcomes
- Risk and Safety Analysis
- Frailty in Older Adults
University Hospital Waterford
2023
University of Kansas
2021
Biomedical Advanced Research and Development Authority
2021
Stroke Association
2014-2018
Dorset HealthCare University NHS Foundation Trust
2015-2017
University of Kansas Medical Center
2017
Harry Perkins Institute of Medical Research
2014
University of California, Irvine
2010
Manly Hospital
1999
Cognitive stimulation therapy (CST) is a well-established group psychosocial intervention for people with dementia. There evidence that home-based programmes of cognitive delivered by family caregivers may benefit both the person and caregiver. However, no previous studies have evaluated caregiver-delivered CST. This study aimed to evaluate effectiveness home-based, caregiver-led individual (iCST) program in (i) improving cognition quality life (QoL) dementia (ii) mental physical health...
Background Group cognitive stimulation therapy programmes can benefit cognition and quality of life for people with dementia. Evidence home-based, carer-led interventions is limited. Objectives To evaluate the clinical effectiveness cost-effectiveness carer-delivered individual (iCST) dementia their family carers, compared treatment as usual (TAU). Design A multicentre, single-blind, randomised controlled trial assessing cost-effectiveness. Assessments were at baseline, 13 weeks 26 (primary...
Parent-report of child homework problems was examined as a treatment outcome variable in the MTA–Multimodal Treatment Study Children with Attention-Deficit/Hyperactivity Disorder (ADHD). Five hundred seventy-nine children ages 7.0 to 9.9 were randomly assigned either medication management, behavioral treatment, combination or routine community care. Results showed that only participants who received (behavioral and combined treatment) demonstrated sustained improvements comparison The...
A discrete choice experiment (DCE) is a method used to elicit participants’ preferences and the relative importance of different attributes levels within decision-making process. DCEs have become popular in healthcare; however, approaches identify attributes/levels influencing decision interest selection methods for their inclusion DCE are under-reported. Our objectives were: explore development process select/present from identified range that may be influential; describe systematic...
Background Treatment with intravenous alteplase for eligible patients acute ischemic stroke is underused, variation in treatment rates across the UK. This study sought to elucidate factors influencing clinicians’ decision-making about this thrombolytic treatment. Methods A discrete choice experiment using hypothetical patient vignettes framed around areas of clinical uncertainty was conducted UK-based clinicians. Mixed logit regression analyses were on data. Results total 138 clinicians...
This study examined the prevalence and nature of personality change in 99 patients with dementia Alzheimer type multi-infarct dementia. Personality was assessed using an informant-rated inventory patient's before after onset dementia, difference equating to a personality. characteristics were related patients' age sex, duration illness, degree cognitive impairment, presence grasp reflex, extrapyramidal signs. found be almost universal negative particularly associated severity longer...
Background Intravenous thrombolysis for patients with acute ischaemic stroke is underused (only 80% of eligible receive it) and there variation in its use across the UK. Previously, might have been explained by structural differences; however, continuing may reflect differences clinical decision-making regarding eligibility treatment. This could lead to underuse, or result inappropriate use, thrombolysis. Objectives To identify factors which contribute in, influence, clinicians’ about...
Sepsis is a life-threatening infection that affects over 1.7 million Americans annually. Low-volume rural hospitals have worse sepsis outcomes, and emergency department (ED)-based telemedicine (tele-ED) has been one promising strategy for improving care. The objective of this study to evaluate the impact tele-ED consultation on care outcomes in ED patients. TELEvISED multicenter (n = 25) retrospective propensity-matched comparative effectiveness patients mature network. Telemedicine-exposed...
It has long been known that people living with severe mental illness (e.g.schizophrenia, schizoaffective disorder, or bipolar disorder) have a life expectancy is 15-25+ years earlier than of the general population, mostly due to physical health problems such as cardiovascular disease (1-4).However, access and uptake appropriate screening intervention for less common in this population (5,6).There now increasing recognition represents an unacceptable inequity service outcomes (7,8).The Sydney...
Abstract Background Priority actions within the National Dementia Strategy are to ensure early diagnosis of dementia and develop appropriate referral pathways interventions support patients. One element is consideration memory services for patients who delirium acute hospital setting, which may suggest possible underlying cognitive impairment. We examined effect identification via an inpatient frailty service on this process. Methods Over a 9-month period (September 2022–May 2023),...