A5078977881- Reproductive tract infections research
- Reproductive System and Pregnancy
- Reproductive Physiology in Livestock
- Microbial infections and disease research
- Vector-borne infectious diseases
- Mycobacterium research and diagnosis
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Tuberculosis Research and Epidemiology
- Rabies epidemiology and control
- Clostridium difficile and Clostridium perfringens research
- Reproductive Health and Contraception
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Cervical Cancer and HPV Research
- Burn Injury Management and Outcomes
- Animal Disease Management and Epidemiology
- Syphilis Diagnosis and Treatment
- Diphtheria, Corynebacterium, and Tetanus
- Coccidia and coccidiosis research
- Insect and Pesticide Research
- Virus-based gene therapy research
- Diagnosis and treatment of tuberculosis
- Streptococcal Infections and Treatments
Universidad de Murcia
2014-2024
Universidad Complutense de Madrid
2015-2018
Harris Birthright Research Centre for Fetal Medicine
2016
King's College Hospital
2016
Servicio Gallego de Salud
2007
Universidad de León
2003-2004
Instituto de Biotecnología de León
2003
In north-western Spain, piroplamosis caused by Theileria annae is now recognized as a serious problem because veterinarians, despite being aware of the clinical signs piroplasmosis, lack necessary information on its epidemiology or specific diagnostic tools for management. This, along with fact that T. infection also refractory to current treatments, prompted this study designed assess presentation and diagnosis largely unknown parasitic disease in dogs. One hundred twenty dogs NW Spain...
Piroplasmosis is caused by several species of protozoa such as the Babesia microti-like piroplasm (Bml), an emerging blood protozoan also known Theileria annae or vulpes. Infection Bml was first reported in dogs Spain where it endemic today. Recently, a high prevalence has been increasingly detected red foxes (Vulpes vulpes) European countries. The objective this study to determine infection levels parasite from Galicia, NW Spain, and ticks infestation these carnivores, they are so far...
Identifying the aetiological agent of atypical pneumonia in human can sometimes be a tedious process, especially cases where Mycoplasma pneumoniae, Legionella species and Chlamydia pneumoniae are ruled out. In such cases, correct anamnesis patient is basic to clarify which pathogens might have produced infection. For this reason, health professionals including veterinarians laboratory personnel working with zoonotic should keep their doctors informed.A case linked abortus reported. A...
Piroplasmosis caused by the Babesia microti-like piroplasm (Bml) is increasingly being detected in dogs Europe. Sick show acute disease with severe anaemia associated thrombocytopenia a poor response to current available drugs. This study assesses safety and tolerance of three treatments compares their efficacy over full year follow up naturally infected Bml.Fifty-nine Bml were randomly assigned treatment group: imidocarb dipropionate (5 mg/kg SC, 2 doses 14 d apart) (IMI); atovaquone (13.3...
To evaluate the performance of screening for all stillbirths and those due to impaired placentation unexplained or other causes using a combination maternal factors, fetal biometry uterine artery pulsatility index (UtA-PI) at 19-24 weeks' gestation compare this with that by UtA-PI alone.This was prospective study 70 003 singleton pregnancies including 69 735 live births 268 (0.38%) antepartum stillbirths; 159 (59%) were secondary 109 (41%) causes. Multivariable logistic regression analysis...
A Chlamydophila abortus-induced abortion model was carried out on the basis of experimental infection ewes at day 75 gestation. The induced abortions and birth weak lambs during last 3 weeks pregnancy. To study kinetics in placenta other organs, infected were killed 105, 120, 130 days gestation also several after or parturition. Infected developed a systemic that caused mild transient pneumonia focal hepatitis. Pathologic changes observed placentas 120 gestation, although lesions varied...
A histological study was carried out on 58 formalin-fixed and paraffin-embedded samples of placenta from sheep goats that had aborted, the placental lesions were graded. Sequential sections each cotyledon then immunostained with specific antibodies used for PCR detection Chlamydophila abortus, Coxiella burnetii, Salmonella Abortusovis, Brucella melitensis, Listeria monocytogenes Toxoplasma gondii. Most cotyledons showed different degrees placentitis. The proportional agreement between two...
ABSTRACT A Th1 immune response involving gamma interferon (IFN-γ) production is required to eliminate Chlamydophila abortus infections. In this study, the role of interleukin-12 (IL-12) in protecting against C. infection was investigated using IL-12 −/− and wild-type (WT) C57BL/6 mice determine Th1-promoting cytokine. were able a primary infection. However, there delay clearance bacteria when infected with sublethal dose , being associated lower IFN-γ. The low level IFN-γ essential for...
ABSTRACT The resolution of Chlamydophila abortus ( Chlamydia psittaci serotype 1) infection is dependent on gamma interferon and CD8 + T cells, classically, B cells have been considered to play a minimal role in host defense. the immune response was studied by using model mice with genetically modified immunoglobulin M transmembrane domains (μMT). In absence C. leads an acute severe fatal disease that involves disseminated intravascular coagulation syndrome. μMT displayed increased level...
Abstract A copy of the bovine chymosin gene ( chy ) with a codon usage optimized for its expression in Aspergillus awamori was constructed starting from synthetic oligonucleotides. To study ability this filamentous fungus to secrete prochymosin, two plasmids were which transcriptional, translational, and secretory control regions A. nidulans gpd pep B genes coupled either preprochymosin or prochymosin genes. Secretion protein enzymatically immunologically indistinguishable achieved...
Abstract Lyme disease and the spotted fever group rickettsiosis, involve bacteria belonging to genus Borrelia Rickettsia , respectively. These infections are most important tick-borne zoonotic diseases involving ticks as vectors. Descriptive epidemiological studies essential determine animal hosts involved in maintenance of these diseases. In present study, 94 tick pool samples from 15 different host species located Region Murcia (southeastern, Spain) were analysed. Ticks morphologically...
Between 2010 and 2013, an outbreak of caseous lymphadenitis (CLA) occurred in a captive stock Iberian ibexes (Capra pyrenaica, Schinz 1838) maintained for conservation purposes the National Game Reserve 'Ports de Tortosa i Beseit' (PTB), northeastern Spain. The aim this study was to assess CLA status free-ranging donor population ibexes. An ELISA test detect antibodies performed 360 hunter-harvested between 2007 2013. A spatial analysis recursive partitioning approaches with regression tree...