A5039426038- Proteins in Food Systems
- Meat and Animal Product Quality
- Vehicle Dynamics and Control Systems
- Microencapsulation and Drying Processes
- Industrial Technology and Control Systems
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- Radiopharmaceutical Chemistry and Applications
- Advanced Battery Technologies Research
- Nanoplatforms for cancer theranostics
- Semiconductor materials and devices
- Metal-Organic Frameworks: Synthesis and Applications
- Traffic control and management
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced Sensor and Control Systems
- Electric Motor Design and Analysis
- Photonic and Optical Devices
- X-ray Diffraction in Crystallography
- Catalytic C–H Functionalization Methods
- Peptidase Inhibition and Analysis
- Graph theory and applications
- Electric and Hybrid Vehicle Technologies
- Advanced Fiber Optic Sensors
- Advanced Computational Techniques and Applications
- Autonomous Vehicle Technology and Safety
Northeast Agricultural University
2022-2025
Beijing Anding Hospital
2024
Nanchang University
2002-2024
Huazhong University of Science and Technology
2021-2024
Tongji University
2013-2024
Eli Lilly (United States)
2011-2024
Peking University First Hospital
2020-2024
Peking University
2020-2024
Chinese Academy of Sciences
1995-2024
Institute of Acoustics
2024
We designed and synthesized a new luminescent metal–organic framework (LMOF). LMOF-241 is highly porous emits strong blue light with high efficiency. demonstrate for the first time that very fast extremely sensitive optical detection can be achieved, making use of fluorescence quenching an LMOF material. The compound responsive to Aflatoxin B1 at parts per billion level, which makes it best performing luminescence-based chemical sensor date. studied electronic properties selected mycotoxins,...
Abstract Atomic layer deposition (ALD) is a thin-film fabrication technique that has great potential in nanofabrication. Based on its self-limiting surface reactions, ALD excellent conformality, sub-nanometer thickness control, and good process compatibility. These merits promote the industrial research applications of various fields. This article provides an introduction to highlights semiconductors, pan-semiconductors, environment energy, other The key nodes integrated circuits are...
Smad7 is a regulatory Smad protein that able to antagonize signal transduction by transforming growth factor-β (TGF-β) and activin receptors. To characterize the regulation of at transcriptional level, we isolated promoter region mouse gene. When luciferase reporter gene (−408 +112 bp) was expressed in human hepatoma (HepG2) cells, its activity increased following TGF-β or treatment. In addition, this stimulated ectopic expression Smad3 as well constitutively active receptors, indicating...
Biological differences in sensory processing between human and model organisms may present significant obstacles to translational approaches treating chronic pain. To better understand the physiology of neurons, we performed whole-cell patch-clamp recordings from 141 dorsal root ganglion (hDRG) neurons 5 young adult donors without Nearly all small-diameter hDRG (<50 μm) displayed an inflection on descending slope action potential, a defining feature rodent nociceptive neurons. A high...
A new layered MOF material [Co(Hoba)(2)·2H(2)O] (1) (H(2)oba = 4,4'-oxybis(benzoic acid)) has been synthesized and used as a highly recyclable heterogeneous catalyst for olefin epoxidation reactions. Both high conversion (96%) selectivity of epoxide products are achieved.
α-Conotoxin Vc1.1 is a small disulfide-bonded peptide from the venom of marine cone snail Conus victoriae. has antinociceptive actions in animal models neuropathic pain, but its applicability to inhibiting human dorsal root ganglion (DRG) neuroexcitability and reducing chronic visceral pain (CVP) unknown.We determined inhibitory on DRG neurons mouse colonic sensory afferents healthy hypersensitivity (CVH) states. In mice, nociception was assessed by neuronal activation within spinal cord...
Optical computing and optical neural network have gained increasing attention in recent years because of their potential advantages parallel processing at the speed light low power consumption by comparison with electronic computing. The implementation fundamental building blocks a digital computer, i.e. logic gates, has been investigated extensively past few decades. gate is an alternative approach to various analogue architectures. In this paper, latest development different kinds...
Abstract Genetic encoding of noncanonical amino acid (ncAA) for site-specific protein modification has been widely applied many biological and therapeutic applications. To efficiently prepare homogeneous multiconjugates, we design two encodable acids (ncAAs), 4-(6-(3-azidopropyl)-s-tetrazin-3-yl) phenylalanine (pTAF) 3-(6-(3-azidopropyl)-s-tetrazin-3-yl) (mTAF), containing mutually orthogonal bioorthogonal azide tetrazine reaction handles. Recombinant proteins antibody fragments the TAFs can...
A flexible microporous metal organic framework structure, [Zn2(bpdc)2bpe]·2DMF, exhibits high selectivity in adsorbing CO2 over N2, CH4 and a number of other small gases at room temperature low pressure.
Abstract Surgery is an efficient way to treat localized prostate cancer (PCa), however, it challenging demarcate rapidly and accurately the tumor boundary intraoperatively, as existing detection methods are seldom performed in real-time. To overcome those limitations, we develop a fluorescent molecular rotor that specifically targets prostate-specific membrane antigen (PSMA), established marker for PCa. The probes have picomolar affinity (IC 50 = 63-118 pM) PSMA generate virtually...