Matthew S. Delfiner

ORCID: 0000-0002-0967-1017
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About
Contact & Profiles
Research Areas
  • Heart Rate Variability and Autonomic Control
  • Mechanical Circulatory Support Devices
  • Cardiac Arrest and Resuscitation
  • Cardiac Imaging and Diagnostics
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Disease and Adiposity
  • Cardiac Arrhythmias and Treatments
  • Cardiovascular Effects of Exercise
  • Heart Failure Treatment and Management
  • Pulmonary Hypertension Research and Treatments
  • Hormonal Regulation and Hypertension
  • Atrial Fibrillation Management and Outcomes
  • Clinical Laboratory Practices and Quality Control
  • Heart rate and cardiovascular health
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Function and Risk Factors
  • Congenital Heart Disease Studies
  • Cardiac electrophysiology and arrhythmias
  • RNA modifications and cancer
  • Clinical Reasoning and Diagnostic Skills
  • Blood Pressure and Hypertension Studies
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Cardiovascular and Diving-Related Complications
  • Elevator Systems and Control
  • Takotsubo Cardiomyopathy and Associated Phenomena

University of Pennsylvania
2024

Temple University
2021-2024

Hospital of the University of Pennsylvania
2024

Temple University Hospital
2019-2022

Temple University Health System
2022

New York Institute of Technology
2015-2018

Background Laboratory diagnostic tests have an essential role in patient care, and the increasing number of medical health professions schools focusing on teaching laboratory medicine to pre-clinical students reflects this importance. However, data validating pedagogical methods that best influence students' comprehension interpretation not been well described. The Gram stain is a simple yet significant frequently used test clinical setting helps classify bacteria into two major groups,...

10.1371/journal.pone.0163658 article EN cc-by PLoS ONE 2016-10-06

The Impella 5.5 is increasingly used as a bridge to recovery or heart replacement therapies despite lack of clinical trial evidence. We report real-world outcomes and hemodynamic effects 150 consecutive patients from single, high-volume center. Primary outcome was incidence recovery, durable left ventricular assist device (LVAD), transplant compared with death at 90 days. Secondary included trends upgrade veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. composite endpoint...

10.1097/mat.0000000000002331 article EN ASAIO Journal 2024-10-14

Abstract In one of the earliest reports from China during COVID-19, it was noted that over 20% patients hospitalized with disease had significant elevations troponin, a marker myocardial tissue damage, put them at higher risk. hypothesis-independent whole exome sequencing (WES) study in COVID-19 diverse ancestry, we observed putative enrichment pathogenic variants genes known to be involved pathogenesis cardiomyopathy. This observation led us hypothesize high morbidity and mortality these...

10.1007/s00109-024-02510-z article EN cc-by Journal of Molecular Medicine 2024-12-27

A 57-year-old woman with end-stage renal disease arteriovenous fistula (AVF) on her left upper extremity was referred for right heart catheterization after diagnosis of mitral regurgitation (MR) by clinical examination and echocardiography.The severity the MR initially unclear due to varying murmur intensities at separate visits.Hemodynamic measurements cardiac output assumed Fick equation were measured baseline manual compression AVF.At baseline, end-expiratory pulmonary artery wedge...

10.1161/circheartfailure.123.010733 article EN Circulation Heart Failure 2023-07-12

Introduction Both vagal (VS) and sympathetic (SS) stimulation have been shown to increase atrial fibrillation (AF) inducibility, with VS being more arrhythmogenic in normal hearts. Heart failure (HF) results autonomic dysfunction, characterized by activation withdrawal, is associated an increased incidence of AF. However, it unknown whether failing hearts respond differently AF inducibility. Methods Myocardial infarction was produced left anterior coronary artery ligation 9 rats, 10...

10.1096/fasebj.30.1_supplement.1274.11 article EN The FASEB Journal 2016-04-01

BackgroundMineralocorticoid receptor antagonists (MRA) have been shown to improve mortality in patients with heart failure (HF) reduced ejection fraction (EF) and morbidity those preserved EF. It is unknown if cardiac anatomy changes over time prescribed MRAs compared without a prescription.HypothesisPatients improved echocardiographic measurements controls.MethodsThe electronic medical record was queried find who were MRA along age-matched controls. Each subject had beta blocker (BB),...

10.1016/j.cardfail.2019.07.116 article EN other-oa Journal of Cardiac Failure 2019-08-01

Abstract Background COVID-19 has affected individuals across the globe, and those with cardiac implantable electronic devices (CIEDs) likely represent a high-risk group. These can be interrogated to reveal information about patient activity, heart rate parameters, respiratory rate. Case summary Four patients CIEDs left ventricular dysfunction were admitted single institution for infection. Each survived hospitalization, none required intensive care. Retrospectively, CIED interrogation...

10.1093/ehjcr/ytac404 article EN cc-by-nc European Heart Journal - Case Reports 2022-10-01

Introduction:Stress Cardiomyopathy (SCM), is an acute reversible myocardial injury associated with transient left ventricular dysfunction. Risk factors include female sex, post-menopause, anxiety, depression, schizophrenia, asthma and chronic obstructive pulmonary disease, diabetes, substance use. Obesity has increased sympathetic tone state of metabolic stress, both which are similar in etiology to SCM. We postulate that obesity may have high prevalence patients Methods: queried the...

10.1161/circ.146.suppl_1.13332 article EN Circulation 2022-11-08

Introduction: Coronary artery calcium score (CACS) is a known predictor of cardiac events, however its association with inpatient mortality in COVID-19 infection remains unknown. Hypothesis: We hypothesized that elevated CACS associated increased patients COVID-19. Methods: Inpatients between March and May, 2020 at single center were identified. All had non-contrast chest CT during admission, Multi-Ethnic Study Atherosclerosis (MESA) percentile retrospectively measured. Patients grouped...

10.1161/circ.144.suppl_1.10256 article EN Circulation 2021-11-16
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