- Heart Rate Variability and Autonomic Control
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Hormonal Regulation and Hypertension
- Atrial Fibrillation Management and Outcomes
- Clinical Laboratory Practices and Quality Control
- Heart rate and cardiovascular health
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- RNA modifications and cancer
- Clinical Reasoning and Diagnostic Skills
- Blood Pressure and Hypertension Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiovascular and Diving-Related Complications
- Elevator Systems and Control
- Takotsubo Cardiomyopathy and Associated Phenomena
University of Pennsylvania
2024
Temple University
2021-2024
Hospital of the University of Pennsylvania
2024
Temple University Hospital
2019-2022
Temple University Health System
2022
New York Institute of Technology
2015-2018
Background Laboratory diagnostic tests have an essential role in patient care, and the increasing number of medical health professions schools focusing on teaching laboratory medicine to pre-clinical students reflects this importance. However, data validating pedagogical methods that best influence students' comprehension interpretation not been well described. The Gram stain is a simple yet significant frequently used test clinical setting helps classify bacteria into two major groups,...
The Impella 5.5 is increasingly used as a bridge to recovery or heart replacement therapies despite lack of clinical trial evidence. We report real-world outcomes and hemodynamic effects 150 consecutive patients from single, high-volume center. Primary outcome was incidence recovery, durable left ventricular assist device (LVAD), transplant compared with death at 90 days. Secondary included trends upgrade veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. composite endpoint...
Abstract In one of the earliest reports from China during COVID-19, it was noted that over 20% patients hospitalized with disease had significant elevations troponin, a marker myocardial tissue damage, put them at higher risk. hypothesis-independent whole exome sequencing (WES) study in COVID-19 diverse ancestry, we observed putative enrichment pathogenic variants genes known to be involved pathogenesis cardiomyopathy. This observation led us hypothesize high morbidity and mortality these...
A 57-year-old woman with end-stage renal disease arteriovenous fistula (AVF) on her left upper extremity was referred for right heart catheterization after diagnosis of mitral regurgitation (MR) by clinical examination and echocardiography.The severity the MR initially unclear due to varying murmur intensities at separate visits.Hemodynamic measurements cardiac output assumed Fick equation were measured baseline manual compression AVF.At baseline, end-expiratory pulmonary artery wedge...
Introduction Both vagal (VS) and sympathetic (SS) stimulation have been shown to increase atrial fibrillation (AF) inducibility, with VS being more arrhythmogenic in normal hearts. Heart failure (HF) results autonomic dysfunction, characterized by activation withdrawal, is associated an increased incidence of AF. However, it unknown whether failing hearts respond differently AF inducibility. Methods Myocardial infarction was produced left anterior coronary artery ligation 9 rats, 10...
BackgroundMineralocorticoid receptor antagonists (MRA) have been shown to improve mortality in patients with heart failure (HF) reduced ejection fraction (EF) and morbidity those preserved EF. It is unknown if cardiac anatomy changes over time prescribed MRAs compared without a prescription.HypothesisPatients improved echocardiographic measurements controls.MethodsThe electronic medical record was queried find who were MRA along age-matched controls. Each subject had beta blocker (BB),...
Abstract Background COVID-19 has affected individuals across the globe, and those with cardiac implantable electronic devices (CIEDs) likely represent a high-risk group. These can be interrogated to reveal information about patient activity, heart rate parameters, respiratory rate. Case summary Four patients CIEDs left ventricular dysfunction were admitted single institution for infection. Each survived hospitalization, none required intensive care. Retrospectively, CIED interrogation...
Introduction:Stress Cardiomyopathy (SCM), is an acute reversible myocardial injury associated with transient left ventricular dysfunction. Risk factors include female sex, post-menopause, anxiety, depression, schizophrenia, asthma and chronic obstructive pulmonary disease, diabetes, substance use. Obesity has increased sympathetic tone state of metabolic stress, both which are similar in etiology to SCM. We postulate that obesity may have high prevalence patients Methods: queried the...
Introduction: Coronary artery calcium score (CACS) is a known predictor of cardiac events, however its association with inpatient mortality in COVID-19 infection remains unknown. Hypothesis: We hypothesized that elevated CACS associated increased patients COVID-19. Methods: Inpatients between March and May, 2020 at single center were identified. All had non-contrast chest CT during admission, Multi-Ethnic Study Atherosclerosis (MESA) percentile retrospectively measured. Patients grouped...