Rationale: Ulcerative colitis (UC), a typical kind of inflammatory bowel disease (IBD), is an idiopathic chronic intestinal inflammation.Conventional therapeutic strategies mainly focus on the rebalance pro-inflammation and anti-inflammation cytokines, whereas targeting damaged barriers, imbalanced microbiota dysregulated mucosal immune responses in UC remain big challenge.The objective this study was to develop turmeric-derived nanovesicles (TNVs) for alleviation explore underlying...

Over decades, the source-function relationships of bioactive polysaccharides have been progressively investigated, however, it is still unclear how a defined structure may conduce to bioactivities polysaccharides. To explore structure-function relationship fungus polysaccharides, we employed dextran sulfate sodium (DSS)‐induced colitis mouse model compare anti-inflammatory activity two from Dictyophora indusiata (DIP) and Tremella fuciformis (TFP), which exhibit distinct glycosidic linkages....

Ulcerative colitis (UC) is a chronic recurrent idiopathic disease characterized by damage to the colonic epithelial barrier and disruption of inflammatory homeostasis. At present, there no curative therapy for UC, development effective low-cost therapies strongly advocated. Multiple lines evidence support that tannic acid (TA) berberine (BBR), two active ingredients derived from Chinese herb pair (Rhei Radix et Rhizoma Coptidis Rhizoma), have promising therapeutic effects on inflammation....

With the development of synthesis technology, modified messenger RNA (mRNA) has emerged as a novel category therapeutic agents for broad diseases. However, effective intracellular delivery mRNA remains challenging, especially its sensitivity to enzymatic degradation. Here, we propose polyphenol-assisted handy strategy efficient in vivo IL-10 mRNA. binds polyphenol ellagic acid through supramolecular binding yield negatively charged core, followed by complexing with linear polyetherimide and...

Background Grafting is an established practice for asexual propagation in horticultural and agricultural crops. The study on graft unions has become of interest horticulturists using proteomic genomic techniques to observe transfer genetic material signal transduction pathways from root shoot root. Another reason the was potentially resistance against abiotic stresses. Using physiological analyses, we investigated (rootstock scions) tomato genotypes exposed standard-normal (23/23 25/18°C...

Insufficient exposure to light in the winter may result a longer production periods and lower quality of seedlings greenhouses for plug growers. Supplementary artificial lighting be one solution this problem. The objective study was assess effects duration supplementary on growth development two watermelon cultivars, ‘Speed’ ‘Sambok Honey’ grafted onto ‘RS-Dongjanggun’ bottle gourd rootstocks (Lagenaria siceraria Stanld). Seedlings were grown 10 days glasshouse with an average daily natural...

Browning is prevalent in tissue cultures of Paeonia lactiflora Pall. (herbaceous peony), and severely affects restricts the growth differentiation explants. In this study, dipping excised explants a sodium chloride (NaCl) solution as pretreatment, adding polyvinyl pyrrolidone (PVP) to culture medium, storing planted at 4 °C for 24 h, transferring new medium after h were considered browning-suppression methods herbaceous peony ‘Festival Maxima’. The treated petal cultured room with 16-hour...

Plants are exposed to numerous biotic and abiotic stresses, light is one of the most important factors that influences plant morphology. This study was carried out examine how lighting direction affected morphology by investigating growth parameters, epidermal cell elongation, stomatal properties, physiological changes. Seedlings two head lettuce (Lactuca sativa L.) cultivars, Caesar Green Polla, were subjected a 12 h photoperiod with 300 μmol·m-2·s-1 photosynthetic photon flux density...

Ulcerative colitis (UC) is a high incidence disease worldwide and clinically presents as relapsing incurable inflammation of the colon. Bilirubin (BR), natural antioxidant with significant anti-colitic effects, utilized in preclinical studies an intestinal therapy. Due to their water-insolubility, design BR-based agents usually involves complicated chemosynthetic processes, introducing various uncertainties BR development. After screening numerous materials, it identified that chondroitin...

Lower quality and longer production periods of grafted seedlings, especially plug seedlings fruit vegetables, may result from insufficient amounts light, particularly in rainy seasons winter. Supplemental artificial lighting be a feasible solution to such problems. This study was conducted evaluate light intensity’s influence on the tomato ‘Super Sunload’ Dotaerang’ were onto ‘B-Blocking’ rootstock. To improve their quality, moved glasshouse grown for 10 days. The had combination natural sun...

Commercial strawberries are mainly propagated using daughter plants produced on aerial runners because asexual propagation is faster than seed propagation, and retain the characteristics of mother plant. This study was conducted to investigate effective factors for runner induction, as well molecular mechanisms behind induction. An orthogonal test with 4 (photoperiod, temperature, gibberellin, 6-benzyladenine), each 3 levels performed. Proteins were also extracted from crowns or without...

Guava ( Psidium guajava L.) is a tropical evergreen tree that tolerates wide range of frost-free environments. In recent years, the American market demand for exotic and nutritious fruits, like guava, has been increasing, and, with long harvest period, guava can be potential alternative, high-value cash crop in United States. However, major limitation commercializing cultivation States its low cold tolerance. this article, we studied physiology freezing tolerance acclimation guava....

A hydroponic cultivation system was established to improve the nutraceutical properties of Ligularia fischeri (Ledeb.) Turcz, during which nutrient uptake by plant from solution measured using inductive coupled plasma-atomic emission spectroscopy (ICP-AES). Based on obtained data, macro and micro elements per gram fresh weight calculated. The macro-elements NH4+-N, NO3−-N, K, S, P, Ca, Mg were 1.62, 4.27, 8.41, 1.19, 2.59, 2.79, 0.84 mg·g−1 FW micro-elements B, Fe, Mn, Mo, Cu, Zn 9.91,...

Hydrogen sulfide (H2S) is endogenously produced in plant cells and plays an essential role root development. Given its potential for future agricultural applications, the optimal concentration of sodium hydrosulfide (NaHS, H2S donor) mechanisms development strawberry ‘Seolhyang’ were investigated this study. The results showed that NaHS with a 1.250 mM had positive effect on strawberry. Further experiments exogenous elevated content root. dry weight was increased by treatment, but reduced...

Monkey disease models, which are comparable to humans in terms of genetic, anatomical, and physiological characteristics, important for understanding mechanisms evaluating the efficiency biological treatments. Here, we established an A.suum-induced model asthma cynomolgus monkeys profile airway inflammation remodeling lungs by single-cell RNA sequencing (scRNA-seq). The results hyperresponsiveness remodeling, demonstrated pulmonary function test histological characterization. scRNA-seq...

Supplementary lighting is commonly used in high-quality seedling production. In this study, grafted tomato seedlings were grown for 10 days a glasshouse with 16-h daily supplementary at 100 μmol·m−2·s−1 PPFD (Photosynthetic photon flux density) from either high-pressure sodium (HPS), metal halide (MH), far-red (FR), white LEDs (Light emitting diodes) (W), or mixed (W1R2B1, where the subscript numbers indicate ratio of LED chips) to determine which light sources improve quality. The control...

Artificial light supplementation is widely used in modern agriculture. Due to their numerous advantages, emitting diodes (LEDs) are effectively increase the yield or control development of crops. In present study, effects supplementary morning lighting (SML) with LEDs on physiology and stomatal characteristics strawberry plants were studied, aim awakening plant guard cells before sunrise enabling efficiently photosynthesize immediately after sunrise. Young daughter 'Maehyang' 'Seolhyang'...