A5059216270- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Hormonal and reproductive studies
- Sexuality, Behavior, and Technology
- Genital Health and Disease
- Sexual Differentiation and Disorders
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Organ and Tissue Transplantation Research
- Genetic Syndromes and Imprinting
- Ethics and Legal Issues in Pediatric Healthcare
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Epigenetics and DNA Methylation
- Eating Disorders and Behaviors
- Hepatocellular Carcinoma Treatment and Prognosis
- Sleep and related disorders
- Prenatal Screening and Diagnostics
- Urologic and reproductive health conditions
- Pain Mechanisms and Treatments
- Chronic Kidney Disease and Diabetes
- Autophagy in Disease and Therapy
- Artificial Intelligence in Healthcare and Education
- Healthcare and Venom Research
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
AGH University of Krakow
2024
University of Applied Sciences and Arts of Southern Switzerland
2024
Chengdu University
2011-2016
Stanford University
2012
Harbin Medical University
2011
The University of Texas Health Science Center at Houston
2008-2010
The University of Texas MD Anderson Cancer Center
2003-2009
Boston Children's Hospital
1998
The causal association between modifiable risk factors and erectile dysfunction (ED) remains unclear, which hinders the early identification intervention of patients with ED. present study aimed to clarify 42 predominant
To investigate the prevalence and associated factors of lower urinary tract symptoms suggestive benign prostatic hyperplasia (LUTS/BPH) in Chinese aging males.Data downloaded from China Health Retirement Longitudinal Study (CHARLS) was subjected to descriptive statistics followed by univariate logistic regression multivariate regression.A total 8563 participants with an overall LUTS/BPH 11.97% were enrolled. With aging, increased (p < 0.001). Men aged over 70 years suffered highest 22.70%....
We compared erect penile length after inflatable prosthesis (IPP) implantation with that induced by intracavernosal injection (ICI) before surgery.A total of 11 patients full erections ICI 0.25 mL Trimix (papaverine, phentolamine and prostaglandin E1) at the time color duplex Doppler ultrasonography were enrolled in this study.The subsequently underwent IPP as ultimate treatment for their erectile dysfunction (ED).Erect consequent to was measured 6 weeks, months 1 year surgery.The Sexual...
Background: To investigate the association between lower urinary tract symptoms suggestive of benign prostate hyperplasia (LUTS/BPH) and metabolic syndrome (MetS) in aging Chinese males. Methods: A dataset that included 3,568 non-MetS cases 1,020 MetS (after data cleansing) was downloaded from China Health Retirement Longitudinal Study (CHARLS). balance intergroup covariates, propensity score matching (PSM) employed analyses. Univariate logistic regression multivariate were then performed to...
Lower urinary tract symptoms suggestive of benign prostate hyperplasia (LUTS/BPH) and depression are both increasing in Chinese aging males. However, the relationship still remains unknown. To explore their relationship, a retrospective cohort study based on propensity score matching (PSM) was conducted by analyzing China Health Retirement Longitudinal Study dataset. After data cleaning, total 5125 participants were enrolled subjected to PSM; 1351 pairs matched followed for 2 years. Further...
Sleep has attracted extensive attention due to its significance in health. However, association with erectile dysfunction (ED) is insufficiently investigated. To investigate the potential causal links between sleep traits (insomnia, duration, and chronotype) ED, this study was performed. The single-nucleotide polymorphisms (SNPs) associated insomnia, chronotype were retrieved from previous genome-wide studies (GWAS). A conventional two-sample Mendelian randomization (MR) used estimate ED....
The mechanisms of adenosine and specific receptor subtypes in promoting penile rehabilitation remain unclear. Single-cell RNA sequencing human corpus cavernosum, deaminase (ADA) receptors knock-out mice (ADA
Abstract Background Azathiopurine (AZA) is the classic immunosuppressant for crohn’s disease (CD) and plays a critical role in induction maintenance of remission, facilitation mucosal healing, prevention postoperative recurrence. The incidence azathiopurine-induced leukopenia (AIL) Asians high, posing serious challenge clinical medication. Diyushengbai tablets are synthetic traditional Chinese medicine, widely used to prevent treat caused by chemotherapy. It remains unclear about its...
Neovascularization facilitates tumour growth and metastasis formation. In our laboratory, we attempt to identify clinically available oral efficacious drugs for antiangiogenic activity. Here, report which non-steroidal anti-inflammatory (NSAIDs) can inhibit corneal neovascularization, induced by basic fibroblast factor (bFGF) or vascular endothelial (VEGF). This activity may contribute the known effects of NSAIDs on gastric ulcers, polyps tumours. We found that sulindac was one most potent...
Background The association between snoring and erectile dysfunction (ED) is inconsistent in multiple observational studies. To clarify the causal of on ED, we performed this two-sample Mendelian randomization study. Materials Methods single nucleotide polymorphisms (SNPs) associated with were retrieved from UK biobank cohort 314,449 participants (117,812 cases 196,637 controls). summary statistics ED obtained European ancestry 223,805 subjects (6,175 217,630 Single-variable (MR)...
Chronic kidney disease (CKD) is prevalent globally with limited therapeutic drugs available. To systemically identify novel proteins involved in the pathogenesis of CKD and possible targets, we integrated human plasma proteomes genome-wide association studies (GWASs) CKD, estimated glomerular filtration rate (eGFR) blood urea nitrogen (BUN) to perform proteome-wide study (PWAS), Mendelian Randomization Bayesian colocalization analyses. The single-cell RNA sequencing data healthy mouse...