A5057580431- Nutrition and Health in Aging
- Frailty in Older Adults
- Cannabis and Cannabinoid Research
- Cancer survivorship and care
- Cardiac, Anesthesia and Surgical Outcomes
- Palliative Care and End-of-Life Issues
- Childhood Cancer Survivors' Quality of Life
- Pain Management and Opioid Use
- GDF15 and Related Biomarkers
- Body Composition Measurement Techniques
- Colorectal Cancer Surgical Treatments
- Pharmacological Effects and Toxicity Studies
- Prenatal Substance Exposure Effects
- Global Cancer Incidence and Screening
- Muscle Physiology and Disorders
- Epilepsy research and treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Bipolar Disorder and Treatment
- Cancer-related cognitive impairment studies
- Adenosine and Purinergic Signaling
- Intensive Care Unit Cognitive Disorders
- Forensic Toxicology and Drug Analysis
- Cardiac Valve Diseases and Treatments
- Homelessness and Social Issues
- Muscle metabolism and nutrition
McGill University Health Centre
2013-2024
McGill University
2008-2022
Concordia University
2007-2022
Collège de Maisonneuve
2012-2019
Sante Montreal
2018
Royal Victoria Hospital
2017
Royal Victoria Regional Health Centre
2017
Policlinico S.Orsola-Malpighi
2016
University of Bologna
2016
Cleveland Clinic Florida
2016
Globally, medical cannabis legalization has increased in recent years and is commonly used to treat chronic pain. However, there are few randomized control trials studying indicating expert guidance on how dose administer safely effectively needed.Using a multistage modified Delphi process, twenty global experts across nine countries developed consensus-based recommendations patients with pain.There was consensus that may be considered for experiencing neuropathic, inflammatory, nociplastic,...
<h3>Background</h3> The clinical and epidemiological relevance of different prognostic factors for survival in patients with advanced or terminal cancer remains controversial. <h3>Purposes</h3> To establish the after diagnosis disease to determine predictors survival. <h3>Methods</h3> An inception cohort 227 consecutive aged 18 years older lung, breast, gastrointestinal tract were observed from July 1, 1996, through December 31, 1998. Tumor- treatment-specific, clinical, laboratory,...
BACKGROUND: Although exertional fatigue is directly and negatively related to skeletal muscle mass strength, it currently unknown if these variables are associated with cancer-related (CRF). Therefore, the purpose of this study was determine CRF measures appendicular lean strength in advanced cancer patients (ACP). METHODS AND RESULTS: Eighty-four (48 men, 36 women aged 61.6 ± 13.2 year) newly diagnosed (≤6 months) inoperable (Stages III-IV) gastrointestinal or non-small cell lung...
Abstract Background Cancer associated cachexia affects the majority of cancer patients during course disease and thought to be directly responsible for about a quarter all deaths. Current evidence suggests that pro‐inflammatory state may with this syndrome although molecular mechanisms development are poorly understood. The purpose work was identification key drivers could provide potential point intervention treatment and/or prevention syndrome. Methods Genetically engineered xenograft...
BACKGROUND Although the prediction of duration life patients with end cancer most often relies on clinical estimation survival (CES) made by treating physician, accuracy and practical value CES remains controversial. METHODS The authors prospectively evaluated in an inception population-based cohort 233 who were seen at onset their terminal phase. They also systematically reviewed literature advanced or end-stage MEDLINE, CANCERLIT, EMBASE data bases, using two search strategies developed a...
It remains unclear whether health-related quality of life (HRQoL) measurements from patients and staff can be combined with medical data to predict survival in terminal cancer.The correlations between potential quality-of-life prognostic variables were explored 2 independent cohorts cancer (248 Cohort 1 756 2) after adjusting for clinical demographics using Cox regression models.At the onset phase (Cohort 1), hazards dying increased by 28% presence dyspnea 68% nausea/emesis; however, most...
Important deteriorations in body composition and strength occur need to be accurately measured advanced cancer patients (ACPs). The aim of this study was establish the relationship between a single-frequency bioimpedance analyzer (BIA) dual-energy X-ray absorptiometer (DXA), as well Jamar handgrip dynometer Biodex attachment, determine precision each these instruments ACPs. Eighty-one ACPs with non-small-cell lung gastrointestinal were recruited from McGill University Health Centre...
To evaluate the safety and effectiveness of medical cannabis (MC) in reducing pain concurrent medications patients with cancer.
Background Cachexia affects the majority with advanced cancer. Based on current demographic and clinical factors, it is not possible to predict who will develop cachexia or not. Such variation may, in part, be due genotype. It has recently been proposed extend diagnostic criteria for include a direct measure of low skeletal muscle index (LSMI) addition weight loss (WL). We aimed explore our panel candidate single nucleotide polymorphism (SNPs) association WL +/− computerized...
Pain and symptom control challenges are common in palliative care, the search for other therapeutic strategies is ongoing. Unfortunately, patients their caregivers receiving little information or support from healthcare providers regarding increasingly popular cannabinoid-based medicines (CBM). Clinicians, meanwhile, feel understandably perplexed by discrepancy between available evidence rapid interest which families have demonstrated CBM. There an urgent need to address many that delaying...
This case report describes a patient affected by neuropathic pain syndrome, which was secondary to renal cell carcinoma metastatic the spine, and complicated incidental components somatization. Due rapid development of tolerance toxicity from hydromorphone, rotation methadone made, with decrease morphine equivalent daily dose (MEDD) 1050 36. After 4 mos good relief, switch over back hydromorphone necessary due worsening pain, associated myoclonus sedation methadone; MEDD this time escalated...