A5101613654- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Galectins and Cancer Biology
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Viral Infections and Immunology Research
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Imaging and Diagnostics
- Ear and Head Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Orthopedic Infections and Treatments
- T-cell and B-cell Immunology
- Congenital heart defects research
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Head and Neck Cancer Studies
- Hematological disorders and diagnostics
- Cardiac electrophysiology and arrhythmias
- RNA modifications and cancer
Sichuan University
2007-2021
West China Hospital of Sichuan University
2019-2021
State Key Laboratory of Biotherapy
2017-2018
University of Hong Kong
2010
Institut für Medizinische Informatik, Biometrie und Epidemiologie
2003
Essen University Hospital
2003
The phenotype via conventional cardiac MRI analysis of MYH7 (β-myosin heavy chain)- and MYBPC3 (β-myosin-binding protein C)-associated hypertrophic cardiomyopathy (HCM) groups is similar. Few studies exist on the genotypic-phenotypic association as assessed by machine learning in HCM patients.To explore phenotypic differences based radiomics T1 mapping images between MYBPC3-associated subgroups.Prospective observational study.In all, 102 patients with pathogenic, or likely pathogenic...
Background There is increasing recognition that left atrial (LA) function prognostically important in cardiovascular disease. LA strain a sensitive parameter to describe complex phasic function. However, the prognostic value of participants with idiopathic dilated cardiomyopathy (DCM) remains unclear. Purpose To evaluate derived from cardiac MRI study DCM. Materials and Methods Participants DCM who underwent between June 2012 November 2018 were prospectively enrolled. The fast long-axis...
Background The prognostic value of myocardial trabecular complexity in patients with hypertrophic cardiomyopathy (HCM) is unknown. Purpose To explore the using fractal analysis participants HCM. Materials and Methods authors prospectively enrolled HCM who underwent 3.0-T cardiovascular MRI from August 2011 to October 2017. also 100 age- sex-matched healthy form a comparison group. Trabeculae were quantified cine slices estimate dimension (FD). Participants divided into normal high FD groups...
The prognostic value of left atrial (LA) size and function in hypertrophic cardiomyopathy (HCM) is well recognized, but LA difficult to routinely analyze. Fast long-axis strain (LA-LAS) analysis a novel technique assess on cine cardiovascular magnetic resonance (CMR). We aimed the association between fast LA-LAS adverse clinical outcomes patients with HCM. 359 HCM 100 healthy controls underwent routine CMR imaging. was analyzed by automatically tracking length midpoint posterior wall...
Background: The cardiac Magnetic Resonance Imaging (MRI) characteristics of rare diseases with the hypertrophic cardiomyopathy (HCM) phenotype are not well defined. Methods: Seventy-three sequential patients and 34 their relatives, who have HCM phenotype, were included. All subjects underwent MRI genetic testing. Results: Of these 107 phenotypic HCM, seven identified: four cases LAMP2, one case PRKAG2, TTR mutation, senile systemic amyloidosis. Subjects had diffuse LGE, percentage those LGE...
To determine the angle between four-chamber view and left ventricular outflow tract (LVOT) using live xPlane imaging to study reproducibility of this technique. Live is a technology available on xMatrix transducers that allows simultaneous two different planes section same structure, in real time with two-dimensional resolution. We attempted visualization LVOT second plane by rotating reference line along Y-axis from 0° at step 5° while 4-chamber was being imaged primary plane. recorded...
Das Multiple Myelom ist eine maligne Erkrankung, welche von proliferierenden monoklonalen Plasmazellen (B-Zellen) ausgeht. Es stellt mit 1 % aller Malignome und 43 der Knochentumoren die häufigste primär Erkrankung im Erwachsenenalter dar (Oken MM, Med Clin North Am 1984; 68: 757). Typisch diffuse skelettale Manifestation ausgehend vom Knochenmark. Hauptmanifestationsort das Achsenskelett. Gewöhnlich sind multiple Läsionen in Wirbelsäule, Rippen, Schädel, Becken Femur zu erkennen. Ein...
Objective: This study aimed to explore the genetic epidemiological characteristics in patients with hypertrophic cardiomyopathy (HCM). Methods: We prospectively enrolled 383 unrelated HCM probands who received testing and 3.0 T cardiac MRI examination, including 118 familial 265 sporadic HCM. The diagnosis of is based on diagnostic criteria American Heart Association College Cardiology guidelines. Patients underwent targeted next generation sequencing 117 candidate pathogenic genes...