A5076708893- Algal biology and biofuel production
- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Computational Drug Discovery Methods
- Biocrusts and Microbial Ecology
- Viral gastroenteritis research and epidemiology
- Microbial bioremediation and biosurfactants
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Graphene and Nanomaterials Applications
- Cholinesterase and Neurodegenerative Diseases
- Stress Responses and Cortisol
- Genital Health and Disease
- Nail Diseases and Treatments
- Hepatitis B Virus Studies
- Alzheimer's disease research and treatments
- Hydrogels: synthesis, properties, applications
- Cervical Cancer and HPV Research
- Enzyme Production and Characterization
- Photodynamic Therapy Research Studies
- Galectins and Cancer Biology
- Birth, Development, and Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Bacillus and Francisella bacterial research
- Hepatitis Viruses Studies and Epidemiology
Islamic Azad University, Karaj
2012-2022
Biotechnology Research Center
2020-2022
Islamic Azad University Sanandaj Branch
2017
Islamic Azad University, Science and Research Branch
2008
Prevention of the globally spread zoonotic infection, brucellosis which affects an extensive range hosts is still challenging researchers. There are no approved vaccines for prevention human disease and those used animal have adverse properties, limit their application. We investigated immunological protective effects recombinant 16 kDa outer membrane protein Brucella abortus (Omp16) introduced a new candidate subunit vaccine.Brucella Omp16 gene was cloned in pET-23a expressed Escherichia...
Alzheimer's disease (AD) is an irreversible neurodegenerative condition in which abnormal accumulation of amyloid plaques observed, and for no effective treatment still exist. In recent years, many aromatic small molecules have been observed to anti-amyloid effect, may the potential attenuate AD symptoms. The indole core flavonoid precursor trans-chalcone studied here as representative these group molecules. Formation has induced a rat model AD, after what two compounds were given...
Fungal polysaccharides are well-known for the medicinal properties such as antitumor and immunomodulating effects. Hence, this study evaluated effects of polysaccharide extracted from Fusarium sp. isolated soil samples Karaj district, Alborz, Iran along with its taxonomic study. The filamentous fungus strain FK1 was sample Karaj, Iran. identified based on cultural, morphological 18 S rRNA gene parameters Fusarium. Further, cultured in fermented broth modified (PDB) 10 days at 25 °C. mycelium...
The aim of the study was to suggest a high specific and sensitive blood biomarker for early GC diagnosis.the expression data miRNAs mRNAs were collected from samples patients based on literature mining. Bioinformatics tools databases (PANTHER, TargetScan, miRTarBase, miRDB, STRING, Cytoscape) used predict regulatory relationship. Subsequently, level selected miRNA evaluated in gastritis recognize common between patients.Analysis 40 target genes by MCODE (installed Cytoscape software)...
Background: Campylobacter spp. is recognized as one of the important bacterial agents food borne diseases worldwide. C. jejuni and coli are most frequently reported species causing gastrointestinal disorders in developed some developing countries. Objectives: The goals this survey were to detect differentiate stool specimens determine frequency gastroenteritis children referred Bahonar hospital Karaj city using polymerase chain reaction (PCR). Patients Methods: One hundred sixty collected...
Human Papilloma Virus (HPV) genotypes concordance among sexual couples has been evaluated in many investigations with considerable variations the concordance. However, no such study carried out between Iranian yet.Urogenital specimen from both males and females of were taken transferred to Nilou laboratory for molecular analysis. HPV DNA extraction typing using cobas 4800 platform. Demographic virological data analyzed afterwards.One hundred fourteen enrolled study. The mean age participants...
The Human Papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide. HPV infection in men a serious clinical issue as they could be considered reservoir for inadvertently transmitting to women. Moreover, genital source anogenital cancers men.This cross sectional study was conducted from January 2017 December 2018. Four hundred fifteen asymptomatic who were visited by specialists, referred Nilou laboratory terms high risk (HR) test testing. HR-HPV genotypes...
Cell culture has a crucial role in many applications biotechnology. The production of vaccines, recombinant proteins, tissue engineering, and stem cell therapy all need culture. Most these activities needed adherent cells to move, which should be trypsinized several times until received on large scale. Although trypsin is manufactured from the bovine or porcine pancreas, problem contamination by unwanted animal immune reactions, pathogen reagents main problem.This study investigated...
Pseudomonas aeruginosa has an important role in nosocomial infections.To evaluate biological activity of the detoxified LPS (D-LPS) entrapped into Poly lactic-co-glycolic acid (PLGA) nanoparticles.LPS was extracted and from P. strain PAO1. The D-LPS, conjugated to PLGA nanoparticles with 1-ethyl-3-dimethyl aminopropyl carbodiimide (EDAC) N-hydroxy-succinimide (NHS). connection evaluated by FTIR (Fourier transform infrared), Zetasizer, Atomic Force Microscope (AFM). BALB/c mice injected...