A5102863015- Advanced Neuroimaging Techniques and Applications
- Cerebral Palsy and Movement Disorders
- Traumatic Brain Injury Research
- Musculoskeletal pain and rehabilitation
- Dysphagia Assessment and Management
- Spine and Intervertebral Disc Pathology
- Amyotrophic Lateral Sclerosis Research
- Pain Mechanisms and Treatments
- Esophageal and GI Pathology
- Spinal Dysraphism and Malformations
- Peripheral Nerve Disorders
- Botulinum Toxin and Related Neurological Disorders
- Parkinson's Disease Mechanisms and Treatments
- Phytochemical Studies and Bioactivities
- Hereditary Neurological Disorders
- Advanced MRI Techniques and Applications
- Anesthesia and Pain Management
- Tracheal and airway disorders
- Neurogenetic and Muscular Disorders Research
- Peripheral Neuropathies and Disorders
- Atherosclerosis and Cardiovascular Diseases
- Respiratory Support and Mechanisms
- Spinal Cord Injury Research
- Neuropeptides and Animal Physiology
- Galectins and Cancer Biology
Yeungnam University
2011-2025
Yeungnam University College
2017-2024
Weatherford College
2023
Yeungnam University Medical Center
2023
CrystalGenomics (South Korea)
2023
Ministry of Science
2017-2021
National Research Foundation of Korea
2021
Pain and Rehabilitation Medicine
2011-2019
Christie's
2018
Creative Commons
2018
To assess corticospinal tract involvement in patients with amyotrophic lateral sclerosis (ALS) by correlating diffusion tensor imaging (DTI) measures intra- and extracranial central motor conduction time (CMCT) clinical features of the patients.We investigated 31 ALS normal volunteers DTI measured fractional anisotropy (FA) within tracts extramotor white matter. We CMCT for first dorsal interosseous muscle segmented it into cortical-brainstem (CTX-BS CT) brainstem-cervical root (BS-CV times...
This study investigated the usefulness of somatosensory-evoked potentials (SEP) and motor-evoked (MEP) in predicting motor outcomes patients with intracerebral hemorrhage (ICH) intraventricular (IVH) extension. We retrospectively evaluated 124 ICH IVH extensions. SEPs posterior tibial nerve MEPs tibialis anterior muscles were evaluated. About 30% could walk independently at 6 months from onset. Patients who exhibited SEP both bilateral nerves demonstrated better ambulatory function compared...
<i>Objectives:</i> Contribution by the unaffected hemisphere is one of motor recovery mechanisms following stroke. We attempted to investigate changes in corticospinal tract (CST) at early stage patients with intracerebral hemorrhage (ICH), using diffusion tensor tractography (DTT). <i>Subjects and Methods:</i> Fifty-three consecutive hemiparetic 40 age- sex-matched control subjects were enrolled. DTT was performed a 1.5-tesla system ICH (7–28 days after onset)....
In Brief Study Design. Behavior, mRNA and immunohistochemical assessment of the expression fractalkine (CX3CL1) its receptor (CX3CR1) in a rat model disc herniation by autologous nucleus pulposus (NP) implantation. Objective. To evaluate changes spinal cord their association with pain behavior herniation. Summary Background Data. Chemokines have recently been implicated pathophysiology neuropathic pain. They mediate astrocytic migration microglial proliferation, which are involved regulation...
Exendin-4 (EX4), a glucagon-like peptide-1 receptor (GLP-1R) agonist that regulates blood glucose levels, has been used in the management of type-2 diabetes mellitus. EX4 can be PEGylated to improve its antidiabetic effects by enhancing stability and extending circulation half-life. Here, determine whether is effective for treatment sepsis, C-terminal thiol-specific EX4s with linear maleimide-PEG-2K, -5K, -20K trimeric maleimide-PEG-50K (hereafter referred as EX4-2K, EX4-5K, EX4-20K,...
Extracorporeal shockwave therapy (ESWT) has been suggested as an alternative treatment for reducing spasticity in patients with cerebral palsy (CP). However, the duration of its effect was rarely known. A meta-analysis performed to investigate effectiveness ESWT at controlling CP according follow-up period. We included studies which used manage CP, and compared that a control group. Finally, three were included. In meta-analysis, spasticity, measured using modified Ashworth scale (MAS),...
Abstract Rationale: Although various oral medications and procedures are applied for managing migraine, their efficacy remains limited. To control migraine that does not respond to conventional treatments, we conducted pulsed radiofrequency (PRF) stimulation the greater occipital nerve (GON) in 2 patients. Patient concerns: Patients 1 complained of chronic throbbing, pulsating, tight headaches. Their headache intensities scored 8 7 on a numeric rating scale (NRS), respectively. experienced...
The ascending reticular activating system (ARAS) is responsible for regulation of consciousness. In this study, using diffusion tensor imaging (DTI), we attempted to reconstruct the thalamocortical projections between intralaminar thalamic nuclei and frontoparietal cortex in normal subjects.
Rationale: Despite medication, exercise, and medical intervention, many patients complain of persistent discogenic neck pain. To manage pain, we performed intradiscal pulsed radiofrequency (PRF) stimulation in a patient with chronic pain refractory to oral medication epidural steroid injection. Patient concerns: A 26-year-old man presented numeric rating scale (NRS) score 7 for His was worse when the held one position prolonged period. There no upper extremities. Diagnoses: Discography...
Autism spectrum disorder (ASD) is a complex neurodevelopmental characterized by impaired social communication and interaction, restricted repetitive behavior, interests. The core symptoms of ASD are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (VTA) to nucleus accumbens (NAc) medial prefrontal cortex (mPFC). AST-001 an investigational product currently phase 3 clinical trial for treating ASD, L-serine as API (active...
Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), a subtype of chronic inflammatory polyneuropathy, is non-compressive peripheral nerve disorder. Symptoms MADSAM include asymmetrical weakness deficits in the distribution individual nerves, which are frequently noted distal portion nerves. can be easily misdiagnosed as any various compressive neuropathies. Here, we present case carpal tunnel syndrome (CTS). A 53-year-old woman had bilateral hand (left hand: significant...