A5060977402- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Healthcare Systems and Practices
- Clinical practice guidelines implementation
- Chronic Lymphocytic Leukemia Research
- Health Systems, Economic Evaluations, Quality of Life
- Optimism, Hope, and Well-being
- Multiple Sclerosis Research Studies
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal synovial abnormalities and treatments
- Chronic Disease Management Strategies
- Viral Infections and Immunology Research
- Total Knee Arthroplasty Outcomes
- Lymphoma Diagnosis and Treatment
- Health, Medicine and Society
- Peripheral Neuropathies and Disorders
- Orthopedic Surgery and Rehabilitation
- Dermatological and COVID-19 studies
- Gout, Hyperuricemia, Uric Acid
- Musculoskeletal pain and rehabilitation
- Musculoskeletal Disorders and Rehabilitation
Institute Mutualiste Montsouris
2024
Action Contre la Faim
2020-2022
Mutuelle Générale de l'Éducation Nationale
2021-2022
Hôpital Cochin
2008-2021
Sorbonne Université
2007-2021
Université de Bordeaux
2021
Centre Hospitalier Universitaire de Bordeaux
2021
Centre National de la Recherche Scientifique
2021
Nordic Pharma (France)
2021
Social Action
2021
Flares in rheumatoid arthritis (RA) and axial spondyloarthritis (SpA) may influence physical activity. The aim of this study was to assess longitudinally the association between patient-reported flares activity-tracker-provided steps per minute, using machine learning.This prospective observational (ActConnect) included patients with definite RA or SpA. For a 3-month time period, activity assessed continuously by number steps/minute, consumer grade tracker, were self-assessed weekly....
Abstract Objective Continuous treatment with the anti–tumor necrosis factor α (anti‐TNFα) antibody infliximab is efficacious in ankylosing spondylitis (AS), whereas discontinuation results disease relapse, variable delay. This study was undertaken to compare efficacy of continuous that a regimen adapted symptom recurrence. Methotrexate (MTX) combination also tested. Methods Patients active AS were randomly assigned at week 0 receive every 6 weeks (continuous treatment) or upon recurrence...
The management of spondyloarthritis is challenging and has changed with the development new concepts treatments. To develop practice guidelines for everyday patients (including psoriatic arthritis), by updating previous national international recommendations, based on a review recently published data. A task force multidisciplinary literature group were established. identified issues that remained unresolved. Based existing recommendations recent publications, developed guidelines, which...
Physical activity can be tracked using mobile devices and is recommended in rheumatoid arthritis (RA) axial spondyloarthritis (axSpA) management. The World Health Organization (WHO) recommends at least 150 min per week of moderate to vigorous physical (MVPA).The objectives this study were assess compare its patterns patients with RA axSpA an tracker the feasibility population.This multicentric prospective observational (ActConnect) included who had definite or axSpA, a smartphone. was...
Objectives. To evaluate the reproducibility of clinical synovitis assessments in rheumatoid arthritis and effect variability on Disease Activity Score-28 (DAS28). Methods. Seven healthcare professionals from different cities examined same patients with active non-early (RA; duration > 4 yrs), for whom a treatment change was being considered. There no training session examination to be performed as quickly possible. The assessed 28 joints DAS28 7 (196 joints), then reexamined these (112...
The clinical presentation and outcome of hepatitis E virus (HEV) infection in inflammatory rheumatic diseases are unknown. We aimed to investigate the severity acute HEV risk chronic viral replication patients with arthritides treated immunosuppressive drugs. All rheumatology internal medicine practitioners belonging Club Rhumatismes et Inflammation France were sent newsletters asking for reports arthritides. Baseline characteristics course retrospectively assessed by use a standardized...
Objectives To explore beliefs and apprehensions about disease its treatment in patients with rheumatoid arthritis spondyloarthritis. Methods 25 spondyloarthritis participated semi-structured interviews their treatment. The were performed by trained interviewers participants' homes. recorded the main themes identified content analysis. Results Patients differentiated between underlying cause of disease, which was most frequently as a hereditary or individual predisposition. In arthritis,...
Axial Spondyloarthritis (AxSpA) and chronic low back pain are rheumatic diseases that impact patients' health-related quality of life (HRQoL). In other conditions, HRQoL was positively associated with dispositional optimism, a personality trait. The objective to explore the relationship between optimism in these two diseases. A cross-sectional study performed 2 tertiary care hospitals private practices France. Patients had definite AxSpA or according rheumatologist. generic questionnaire...
Background The evolution of rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) is marked by flares, although their frequency unclear. Flares may impact physical activity. Activity can be assessed objectively using activity trackers. objective was to assess longitudinally the flares association between Methods This prospective observational study (ActConnect) included patients with definite clinician-confirmed RA or axSpA, owning a smartphone. During 3 months, continuously number...
Study Design. Anulus fibrosus cells from rabbits were grown in primary culture 1) to study their ability produce prostaglandin E2 and Type II phospholipase A2, express stromelysin-1 messenger ribonucleic acid; 2) the effect of interleukin 1β on this production proteoglycan aggregation. Objectives. To investigate potency anulus respond by producing degradative inflammatory agents as compared with articular chondrocytes same animal. Summary Background Data. Interleukin has been implicated...
Objective. To evaluate the intraobserver and interobserver reproducibility of B-mode power Doppler (PD) sonography in patients with active long-standing rheumatoid arthritis (RA) comparatively clinical data. Methods. In each 7 being considered for a change their RA treatment regimen, healthcare professionals examined 28 joints used Disease Activity Score 28-joint count (DAS28). Then sonographers twice, using previously published PD grading systems. The reference standard was presence...
Abstract Objective An annual assessment of cardiovascular (CV) risk factors in rheumatoid arthritis (RA) is recommended, but its practical modalities have not been determined. The objective was to assess the feasibility and usefulness a standardized CV RA, performed by rheumatologists during outpatient clinics. Methods We used cross‐sectional design within network rheumatologists. Each rheumatologist included 5 consecutive unselected patients with definite RA. Data collection factors: blood...
Objective. Clinical joint examination (CJE) is less time-consuming than ultrasound (US) in rheumatoid arthritis (RA). Low concordance between CJE and US would indicate that the 2 tests provide different types of information. Knowledge factors associated with CJE/US help to select patients joints for US. Our objective was identify concordance. Methods. Seventy-six RA requiring tumor necrosis factor-α (TNF-α) antagonist therapy were included a prospective, multicenter cohort. In each patient,...
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease, for which the introduction of injectable treatments has had major impact on quality life directly related to disease. The purpose this descriptive study was evaluate usability new autoinjector, intended methotrexate self-administration, based device's design and instructions use (IFU). This multicenter trial included three user groups: group patients with established RA subdivided into two groups according their hand...
Abstract Background Barriers and facilitators to physical activity in inflammatory arthritis can be assessed through the Inflammatory FAcilitators (IFAB) questionnaire. The objective was measure correlation between IFAB self-reported levels. Methods This an international, multicentric, cross-sectional study 2019–20. Consecutive spondyloarthritis (axSpA), rheumatoid (RA) or psoriatic (PsA) patients completed 10-item IFAB, which ranges from − 70 with lower scores indicating more barriers....