A5102752605- Ion Channels and Receptors
- MicroRNA in disease regulation
- Ion channel regulation and function
- Photoreceptor and optogenetics research
- Phytochemicals and Antioxidant Activities
- Circular RNAs in diseases
- Peptidase Inhibition and Analysis
- Connexins and lens biology
- Protein Hydrolysis and Bioactive Peptides
- Bioactive Compounds and Antitumor Agents
- Genomics, phytochemicals, and oxidative stress
- Molecular Communication and Nanonetworks
- Planarian Biology and Electrostimulation
- Cancer-related molecular mechanisms research
- Hearing, Cochlea, Tinnitus, Genetics
- Gestational Diabetes Research and Management
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Muscle metabolism and nutrition
- Obesity, Physical Activity, Diet
- Cell death mechanisms and regulation
- Phytase and its Applications
University of Valparaíso
2018-2021
The transient receptor potential (TRP) ion channel family consists of a broad variety non-selective cation channels that integrate environmental physicochemical signals for dynamic homeostatic control. Involved in cellular physiological processes, TRP are fundamental to the control cell life cycle. from vanilloid (TRPV) have been directly implicated death. TRPV1 is activated by pain-inducing stimuli, including inflammatory endovanilloids and pungent exovanilloids, such as capsaicin (CAP)....
Background: Breast cancer is a malignant disease that represents an important public health burden. The description of new molecular markers can be to diagnosis, classification, and treatment. Transient receptor potential vanilloid 1 (TRPV1) polymodal channel expressed in different neoplastic tissues cell lines breast associated with the regulation tumor growth, neurogenesis, pain, progression cancer. In primary metastatic tumors, TRPV1 during transformation, invasive behavior, resistance...
Objectives Micro RNA s play a role in the development and progression of head neck squamous cell carcinomas ( HNSCC ). Our aim was to study expression miR‐26, miR‐107, miR‐125b, miR‐203 primary with without lymph node metastasis their clinicopathological significance. Materials Methods The micro n = 16) matched node, as well tumors 16), were determined by quantitative RT ‐ PCR analyzed features survival. Results levels miR‐26 p < .05) miR‐125b .01) higher metastatic , while lower....
17β-estradiol is a neuronal survival factor against oxidative stress that triggers its protective effect even in the absence of classical estrogen receptors. The polymodal transient receptor potential vanilloid subtype 1 (TRPV1) channel has been proposed as steroid implied tissue protection damage. We show here TRPV1 sufficient condition for to enhance metabolic performance injured cells. Specifically, expressing cells, application within first three hours avoided H2O2-dependent...
Abstract Optogenetics is a molecular biological technique involving transfection of cells with photosensitive proteins and the subsequent study their effects. The aim this was to evaluate effect blue light on survival HeLa cells, transfected channelrhodopsin‐2 (ChR2). wild‐type were plasmid that contained gene for ChR2. Transfection channel function evaluated by real‐time polymerase chain reaction (RT‐PCR), fluorescence imaging using green fluorescent protein (GFP) flow cytometry...