A5077531095- Sleep and related disorders
- Sleep and Work-Related Fatigue
- Mobile Health and mHealth Applications
- Sleep and Wakefulness Research
- Behavioral Health and Interventions
- Obesity, Physical Activity, Diet
- Health Literacy and Information Accessibility
- Obstructive Sleep Apnea Research
- Workplace Health and Well-being
- Nutritional Studies and Diet
- Pancreatic and Hepatic Oncology Research
- Pancreatic function and diabetes
- Misinformation and Its Impacts
- Food Security and Health in Diverse Populations
- Dementia and Cognitive Impairment Research
- Neuroendocrine Tumor Research Advances
- Media Influence and Health
- Community Health and Development
- Health and Wellbeing Research
- T-cell and B-cell Immunology
- Homelessness and Social Issues
- Climate Change Communication and Perception
- Pediatric health and respiratory diseases
- Technology Use by Older Adults
- Immunotherapy and Immune Responses
Circadian (United States)
2020-2024
Brigham and Women's Hospital
2020-2024
Harvard University
2020-2024
NYU Langone Health
2024
New York University
2013-2020
New York College of Health Professions
2020
Columbia University
2020
Yale University
2020
University of Pretoria
2020
Koch Institute for Integrative Cancer Research At MIT
2019-2020
Mobile apps hold promise for serving as a lifestyle intervention in public health to promote wellness and attenuate chronic conditions, yet little is known about how individuals with illness use or perceive mobile apps.
Significance Small-cell lung cancer (SCLC) is an aggressive carcinoma with few effective treatment options beyond first-line chemotherapy. BH3 mimetics, such as ABT-263, promote apoptosis in SCLC cell lines, but early phase clinical trials demonstrated no significant benefit. Here, we examine the sensitivity of a large panel including SCLC, to ABT-263 and find that high Bcl2-interacting mediator death (BIM) low myeloid leukemia 1 (MCL-1) expression together predict sensitivity. cells...
Although it has become increasingly clear that cancers display extensive cellular heterogeneity, the spatial growth dynamics of genetically distinct clones within developing solid tumours remain poorly understood. Here we leverage mosaic analysis with double markers (MADM) to trace subclonal populations retaining or lacking p53 oncogenic Kras-initiated lung and pancreatic tumours. In both models, constrains progression advanced adenocarcinomas. Comparison lineage-related knockout wild-type...
This article presents findings from two studies that describe news portrayals of cancer causes and prevention in local TV test the effects typical aspects this coverage on cancer-related fatalism overload. Study 1 analyzed content stories focused an October 2002 national sample newspaper (n = 122 television stations; n 60 newspapers). Informed by results analysis, 2 describes a randomized experiment testing volume about 601). indicates as comparatively more certain than newspapers but...
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Subscription RequiredResearch EpochsExamining understandability, information quality, and presence of misinformation in popular YouTube videos on sleep compared to expert-led Rebecca Robbins, MMSci, PhD, Lawrence J. Epstein, MD, Jay M. Iyer, ABcand, Matthew D. Weaver, Sogol Javaheri, Olabimpe Fashanu, MSC, Stacy Loeb, Kristen Monten, BS, Colin Le, Suzanne Bertisch, Jan Van Den Bulck, Stuart F. Quan, MD PhD Address correspondence to: 221 Longwood Avenue, Boston, MA 02115, Email: E-mail...
Over the last decade, health mobile apps have become an increasingly popular tool used by clinicians and researchers to track food consumption exercise. However, many consumer lack technological features for facilitating capture of critical timing details.This study aimed introduce users 11 from US app stores that recorded both dietary intake establish which one would be most appropriate clinical research.To determine a viable use in timing-related study, we evaluated time stamp data,...
Which design features of nutrition infographics make them memorable and compelling?First, we conducted 3 focus groups with a total 28 participants to understand preferred infographic characteristics adults who were mostly in their early 20s. Second, using between subject design, slide show single-image was displayed an independent sample college students young career university employees (N = 50). We assigned randomly either active or passive processing conditions. correlation regression...
Restorative sleep is a commonly used term but poorly defined construct. Few studies have assessed restorative in nationally representative samples. We convened panel of 7 expert physicians and researchers to evaluate enhance available measures sleep. then developed the revised Sleep Questionnaire (REST-Q), which comprises 9 items assessing feelings resulting from prior episode, each with 5-point Likert response scales. Finally, we prevalence high, somewhat, low REST-Q scores sample US adults...
Although manager support is critical for workplace health and wellness efforts, little known about how to best encourage managers make creative or bold steps toward employee wellness. We posit that the right interactions between employees could have lasting impact on To consider might be motivated take an active role in promoting everyday wellness, we used a website survey of worksite (N = 270) investigate tying at least 10% managerial annual salary increases promotion would incentivize...
Introduction: The proportion of university/college students (UCS) consuming alcohol is similar to the number those reporting poor sleep, at approximately 30%, being greater in student athletes (SA). What remains be understood if sleep potentiates risky behaviors. Objective: Our aim was examine association among difficulties, insomnia symptoms, and insufficient on risk driving under influence a sample UCS whether these associations were more pertinent SA. Methods: Data from National...
We receive more information, and from diverse sources, than ever before. In Social Networks Popular Understanding of Science Health: Sharing Disparities (Baltimore: Johns Hopkins University Press), Brian G. Southwell acknowledges the myriad ways in which we receive, exchange, share information. This concise volume (152 pages) holds a timely account work, new old, on information sharing diffusion why technologies originally envisioned as having potential to bring us together spread far wide...
Study objectives Sleep apnea is associated with hypertension, and treatment may improve outcomes. We examine national burden of sleep apnea, rates treatment, whether racial/ethnic disparities exist among patients hypertension. Methods Data from the National Ambulatory Medical Care Survey/National Hospital Survey (NAMCS/NHAMCS), 2005–2012, were analyzed (N = 417,950). identified hypertension patient visits where diagnosis or complaint was recorded. Primary outcome measures study, medication,...