A5013364315- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Allergic Rhinitis and Sensitization
- Oral and Maxillofacial Pathology
- Ferroptosis and cancer prognosis
- Pituitary Gland Disorders and Treatments
- Air Quality and Health Impacts
- Infectious Diseases and Mycology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cancer-related Molecular Pathways
- Helicobacter pylori-related gastroenterology studies
- RNA modifications and cancer
Seoul National University
2020-2024
Background Epithelial to mesenchymal transition (EMT) is associated with the pathophysiology of chronic rhinosinusitis nasal polyp (CRSwNP). Wnt signaling causative for EMT, whereas mechanism in CRSwNP not fully understood. Objective We sought evaluate role EMT using a murine (NP) model and human tissues. Methods Inflammatory markers EMT-related molecules were evaluated NP models adenomatosis polyposis coli (Apc) Min/+ mice activated treated inhibitor, indocyanine green-001 (ICG-001)....
Abstract Chronic colonic inflammation is a feature of cancer and strongly associated with tumorigenesis, but its underlying molecular mechanisms remain poorly understood. Inflammatory conditions increased ITF2 p65 expression both ex vivo in vivo, showed positive correlations. overexpression stabilized protein levels by interfering the binding Parkin to ITF2. More specifically, C-terminus binds N-terminus inhibits ubiquitination, thereby promoting stabilization. acts as E3 ubiquitin ligase...
Neuropilin-1 (NRP1) is expressed on the surface epithelium of respiratory tract and immune cells, demonstrating its possible function in regulating response airway disease. However, role patient with chronic rhinosinusitis (CRS) remains unknown. This study aimed to elucidate NRP1 CRS nasal polyps (CRSwNP).