A5100770048- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Sinusitis and nasal conditions
- Semiconductor materials and devices
- Silicon Carbide Semiconductor Technologies
- Nasal Surgery and Airway Studies
- Esophageal and GI Pathology
- Copper Interconnects and Reliability
- Neuroblastoma Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- T-cell and Retrovirus Studies
- Thyroid and Parathyroid Surgery
- Cancer-related gene regulation
- Obstructive Sleep Apnea Research
- Studies on Chitinases and Chitosanases
- Tea Polyphenols and Effects
- Ga2O3 and related materials
- Renal Transplantation Outcomes and Treatments
- Urinary and Genital Oncology Studies
- Intestinal Malrotation and Obstruction Disorders
- Powder Metallurgy Techniques and Materials
Seoul National University Hospital
2015-2022
Seoul National University Bundang Hospital
2021-2022
Bucheon University
2022
Soonchunhyang University
2022
Seoul National University
1992-2021
Boramae Medical Center
2020-2021
Institute for Basic Science
2021
The University of Tokyo
2021
University of Ulsan
2017
Asan Medical Center
2017
BACKGROUND: Neutrophils present as major inflammatory cells in refractory chronic rhinosinusitis with nasal polyps (CRSwNP), regardless of the endotype. However, their role pathophysiology CRSwNP remains poorly understood. We investigated factors predicting surgical outcomes patients focus on neutrophilic localization. METHODS: employed machine-learning methods such decision tree and random forest models to predict CRSwNP. Immunofluorescence analysis was conducted detect human neutrophil...
A clinical diagnosis of Ménière's disease (MD) is made based on medical history and audiometry findings. The 1995 American Academy Otolaryngology-Head Neck Surgery (AAO-HNS) guidelines requires histopathological confirmation endolymphatic hydrops (EH) for a "certain" MD. Symptoms such as dizziness ear fullness are important diagnostic features; however, the descriptions provided by patients frequently vague non-specific. recently developed magnetic resonance imaging (MRI) protocol to...
Determining the etiology of severe-to-profound sensorineural hearing loss (SP-SNHL) in pediatric subjects is particularly important aiding decision for auditory rehabilitation. We aimed to update etiologic spectrum SP-SNHL by combining internal canal (IAC)-MRI with comprehensive and state-of-the-art genetic testings. From May 2013 September 2020, 119 cochlear implantees under age 15 years were all prospectively recruited. They subjected tests, including exome sequencing, IAC-MRI diagnosis....
The ground-state energy level of an InAs quantum dot (QD) system can be changed from 1070 to 700 nm by changing the aluminum composition in AlxGa1−xAs matrix. For all QDs, lattice-mismatched strains are same as that InAs/GaAs so QDs easily formed. Photoluminescence signals structures were strong at low temperature and stayed relatively high room temperature. results suggest these highly strained alloy matrices could excellent choice for energy-level engineering QDs.
To validate the 8th edition of American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) and investigate whether a modified classification better reflects prognosis.Medical records patients diagnosed with non-metastatic HPV-related OPSCC between 2010 2016 at single institution were retrospectively reviewed. HPV status was determined by immunohistochemical analysis...
Reducing sugars, including monosaccharides, disaccharides, and a trisaccharide, are derivatized by reductive amination with 7-amino-1,3-naphthalene disulfonic acid. Reversed-phase ion-pairing high-performance liquid chromatography is then used to separate these visibly fluorescent, charged conjugates. Isocratic elution triethylamine-acetic acid from phenyl column, C18 columns in series gives good separations of mixture monosaccharides disaccharides trisaccharides. Resolution certain enhanced...
Abstract The slim modiolar electrode has been reported to ensure better proximity than previous conventional perimodiolar electrodes and consistently high scala tympani localization. Nonetheless, variability in exists even among electrodes, still leaving room for further improvement of proximity, which may positively affect functional outcomes. Given this, the pull-back maneuver was increase a cadaveric study, but vivo repositioning effects remain be established. Here we identified that led...
In situ H2 etching and homoepitaxial growth of 4H-SiC were performed on on-axis Si-face substrates using low-pressure chemical vapor deposition. We investigated the effect various temperatures durations surface used optimized characteristics to enhance polytype stability epitaxial layer. It was found that micro-steps at etched play a vital role in enhancing polytype. Homoepitaxial with up 99% successfully grown spread-out without step-bunching during process.
Background and Objectives: Many otologists face a dilemma in the decision-making process of surgical management patients with cochlear nerve (CN) aplasia. The goal this study is to provide fresh evidence on implantation (CI) results CN Materials Methods: We scrutinized functional outcomes 37 ears 21 children bilateral aplasia who underwent unilateral or CI based cross-sectional longitudinal assessments. Results: Categories Auditory Performance (CAP) scores gradually improved throughout...
We describe a compact and stable setup for detecting the optical second harmonics, in which incident plane rotates with respect to sample. The is composed of rotating Fresnel-rhomb optics femtosecond ytterbium-doped fiber-laser source operating at repetition frequency 10 MHz. including laser occupies an area 1 m2 so that intensity fluctuation harmonics can be less than 0.2 % 4 h. present isotropic harmonic signal gold mirror 0.5 pW demonstrate integrity sensitivity setup. also show...
Dendritic cells (DCs) are pivotal antigen-presenting and serve a unique role in initiating immunity. To test the hypothesis that pre-immunization of recipient with certain DC subsets donor origin can influence graft outcome, we have studied effects immunization allogeneic CD4+CD8−CD11c+ dendritic cell (CD4+DC) CD4−CD8+CD11c+ (CD8+DC) on allograft response. Although both immature CD4+DC CD8+DC from DBA/2 were able to prime naive C57BL/6 (B6) T mixed lymphocyte reaction (MLR), exerted more...
There are still debates about timing and effectiveness of cochlear implants (CI) in pediatric subjects with significant residual hearing who do not belong to traditional indication CI. In this study, we aimed investigate the outcomes CI, specifically on improvement pronunciation, among hearing-impaired children already a substantial degree language skills as evaluated by Categories Auditory Perception (CAP) scores or sentence score. Our cohort comprised CI recipients from July 2018 through...
Hepatocellular carcinoma (HCC) is a primary liver cancer with high prevalence and mortality. There are many cases of advanced HCC at the time diagnosis. Treatment methods prognosis different depends on whether metastasis present. Thus, it necessary to make an accurate evaluation Extrahepatic metastases usually occur through hematogenous spread or adjacent organs such as peritoneum. Metastasis urinary bladder alone rare. Here, we report rare case biopsy-proven solitary in 60-year-old woman.A...
Background and Objectives Tracheostomy lead to persistent bacterial colonization of the respiratory tract. Surgical site infection restenosis by pathogenic bacteria is most fatal complication after open airway surgery. The aim this study describe culture results larynx tracheostoma in patients with tracheostomy preoperative, intraoperative underwent Materials Method A retrospective review was performed on 18 who between 2017 2019. Results Pseudomonas or antibiotic resistance were identified...
Abstract Autoimmune and autoinflammatory inner ear diseases (AIED/AID) are characterized by the symptom of sensorineural hearing loss (SNHL). To date, standardized diagnostic tools for AIED/AID lacking, clinically differentiating from chronic otitis media (COM) with SNHL is challenging. This retrospective study aimed to construct a magnetic resonance imaging (MRI)-based decision tree using classification regression (CART) analysis distinguish COM. In total, 67 patients were enrolled between...