An association between psoriasis and cancer risk has been suggested in prior studies, but few have focused on head neck cancers. Using the Korean National Health Insurance Service database, relevance risks was investigated a cross-sectional study of 3,869,264 individuals over 20 years age, who received general health examination 2009 were followed until 2020. Head incidence rates compared with without psoriasis, contributing factors analysed. The significantly increased group non-psoriasis...

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multidimensional disease. In this study, we performed an unsupervised cluster analysis of CRSwNP using routinely available clinical markers. Methods We conducted retrospective review patients treated endoscopic sinus surgery due to medically intractable bilateral from 2009 2017. Unsupervised was patient's features, including age, peripheral blood eosinophil, tissue eosinophilia, Lund‐Mackay computed tomography (CT) scores,...

Objectives. Vertebrobasilar dolichoectasia (VBD), an elongation and distension of vertebrobasilar artery, may present with cranial nerve symptoms due to root compression. The objectives this study are summarize vestibulocochlear manifestations in subjects VBD through a case series discuss the needs thorough oto-neurotologic evaluation before selecting treatment modalities.Methods. Four were reviewed retrospectively. was confirmed by either brain or internal auditory canal magnetic resonance...

Long-term side effects after radiotherapy for organ preservation 'could deteriorate' the laryngeal function. This study intended to identify incidence of severe late dysphagia following multimodal treatment stage III/IV and hypopharyngeal cancer 'to evaluate function larynx'.The medical records patients successfully treated with a approach, including radiotherapy, were retrospectively analyzed. 'Functional larynx was defined as tolerable oral diet without or tracheostoma'.The included 99...

Background/Aims: We investigated the prevalence, associated factors, and comorbidities of high-risk obstructive sleep apnea (OSA) as determined by STOP-BANG questionnaire in a Korean adult population.Methods: Data were obtained from 7,650 adults (aged ≥ 40 years) who participated Korea National Health Nutrition Examination Survey (2019−2020). Multiple logistic regression analyses used to evaluate association socioeconomic status, lifestyle related with OSA (STOP-BANG score, 5−8).Results: The...

Objectives: Recent studies have shown that cochlear duct length (CDL) varies among individuals and could significantly influence the final position of electrode its trajectory in cochlea. Given this, we hypothesized degree modiolar proximity novel slim electrodes, such as CI532 CI632, can also be affected by CDL. To test this hypothesis, retrospectively evaluated individual CDL to determine if there is any significant correlation with proximity. Methods: Fifty-one ears from 38 subjects...

Purpose: To evaluate the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) classification, a clinical scoring system, for predicting disease control status in chronic rhinosinusitis with nasal polyps (CRSwNP) and to investigate prognostic factors.Materials Methods: In total, 134 CRSwNP patients who underwent functional endoscopic sinus surgery after maximal medical treatment were enrolled.These categorized into four groups according JESREC...

Obesity is a significant risk factor for ovarian cancer (OC) and associated with worse outcomes this disease. We assessed the anti-tumorigenic effects of metformin in human OC cell lines genetically engineered mouse model high grade serous under obese lean conditions. Metformin potently inhibited growth dose-dependent manner all four through AMPK/mTOR pathways. Treatment resulted G1 arrest, induction apoptosis, reduction invasion decreased hTERT expression. In K18-gT121+/-; p53fl/fl;...

Objectives/Hypothesis This study aimed to analyze the feasibility of transnasal humidified rapid‐insufflation ventilatory exchange (THRIVE) during laryngeal microsurgery (LMS) and investigated its efficiency application according location lesion. Study Design Retrospective chart review. Methods Patients over 20 years age who underwent LMS without underlying cardiac, pulmonary, or cerebrovascular disease were retrospectively reviewed. Overall, 54 patients with endotracheal intubation (ETI) 44...

Paralysis of the recurrent laryngeal nerves (RLNs), albeit decreased over years, leaves surgeon helpless as there is not much that can be done once it occurs. Nimodipine has been suggested a remedy could accelerate recovery nerve. Our study aimed to examine factors affect rate (RR) and time (TTR) post-thyroidectomy RLN paralysis, with an emphasis on use nimodipine.A total 197 patients who had undergone thyroid parathyroid surgeries were retrospectively reviewed from October 2016 August 2019....

Abstract The slim modiolar electrode has been reported to ensure better proximity than previous conventional perimodiolar electrodes and consistently high scala tympani localization. Nonetheless, variability in exists even among electrodes, still leaving room for further improvement of proximity, which may positively affect functional outcomes. Given this, the pull-back maneuver was increase a cadaveric study, but vivo repositioning effects remain be established. Here we identified that led...

This study evaluated the surgical outcomes of patients with Beckwith-Wiedemann syndrome who underwent tongue-reduction surgery and analyzed whether malocclusion mandibular prognathism caused by macroglossia could be improved. A retrospective medical record review was performed for 11 whose surgically treated. Demographic data, symptoms signs, intraoperative postoperative were evaluated. Surgery a single surgeon using "keyhole" technique, involving midline elliptical excision anterior wedge...

Proton pump inhibitors (PPIs) play a crucial role in managing laryngopharyngeal reflux (LPR), but the optimal dosing regimen remains unclear. We aim to compare effectiveness of same total PPI dose administered twice daily versus once LPR patients.

Abstract Background This study evaluates functional larynx preservation in patients with hypopharyngeal cancer (HPC) and laryngeal (LC) who achieved complete remission following radiotherapy (RT) or concurrent chemoradiation (CCRT). Methods HPC LC treated RT/CCRT from 1999 to 2017 were retrospectively analyzed. Severe late dysphagia tracheostomy cases assessed determine function. Long‐term rate of associated factors evaluated. Results Of 152 (55 HPC, 97 LC), nine developed severe dysphagia,...

Objectives. The transcutaneous approach is a good option for office-based vocal fold injection (VFI). However, precise localization requires extensive experience because the needle tip invisible in small and complex laryngeal spaces. Recently, real-time light-guided VFI (RL-VFI) was proposed as new technique that allows simultaneous under by light guidance. Herein, we aimed to verify feasibility of RL-VFI an vivo canine model explored its clinical usefulness.Methods. device comprised source...

Injury to the external branches of superior laryngeal nerve (EBSLN) is main reported cause inexplicable post-thyroidectomy dysphonia (PTD) without recurrent (RLN) injury. Loré proposed a retrograde thyroidectomy (RT) technique in which pole dissected as final step after Berry ligament division, making this approach advantageous for protecting EBSLN. However, evidence protective effect remains insufficient. We aimed evaluate EBSLN function following RT and conventional (CT) using...

Vocal fold injection (VFI) via the cricothyroid (CT) membrane is used to treat various diseases affecting vocal folds. The technical challenges of this technique are mainly related invisibility needle. Real-time light-guided VFI (RL-VFI) was recently developed for under simultaneous light guidance in CT approach. Herein, we present first clinical trial RL-VFI, which investigated feasibility and safety new unilateral paralysis (VFP). This prospective pilot study enrolled 40 patients, who were...

In this paper, we report on the fabrication, characterisation, and application of new polymeric displays in view production navigation screens transportation industry. Conjugated polymer electroluminescence devices (CPELD) have been fabricated using poly (ppheneylene vinylene) (PPV). study, improvement PPV-based by either adding side groups to structure or copolymerisation. The effects, a group employed during synthesis, PL (Photoluminescence), EL (Electroluminescence) profiles light...

Sternberg's canal is known to result from incomplete fusion of bony compartments constituting the sphenoid bone during developmental process. This study aimed evaluate prevalence and clinical implications canal.

Abstract ABSTRACT Objectives: Metformin is an anti-diabetic drug that has been shown to have anti-tumorgenic effects by behaving as a novel mTOR inhibitor. suppress cancer cell growth, but little known of its potential halt metastatic spread. Thus, our goal was assess the effect metformin on proliferation, adhesion and invasion in ovarian lines. Methods: Four lines, SKOV3, CAOV3, OVCAR3 IGROV1 were used. Cell proliferation assessed MTT assay after exposure metformin. cycle progression...