A5024780264- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ophthalmology and Eye Disorders
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Sympathectomy and Hyperhidrosis Treatments
- Retinopathy of Prematurity Studies
- Pituitary Gland Disorders and Treatments
- Retinal Development and Disorders
- Cerebral Venous Sinus Thrombosis
- Ocular Disorders and Treatments
- Retinal and Macular Surgery
- Connexins and lens biology
- Cannabis and Cannabinoid Research
- Intraoperative Neuromonitoring and Anesthetic Effects
- Ocular Infections and Treatments
- Intracranial Aneurysms: Treatment and Complications
- melanin and skin pigmentation
- Reconstructive Facial Surgery Techniques
- Head and Neck Surgical Oncology
- Sleep and Wakefulness Research
- Biochemical effects in animals
- Rabies epidemiology and control
University of California, Irvine
2014-2024
UC Irvine Health
2016-2019
The California Eye Institute
2016-2017
University of California, San Diego
2004-2006
University College London
2005
Moorfields Eye Hospital
2005
New York Proton Center
2002
University of Milan
2001
New York Medical College
2001
To provide an update of the short-term results combined phacoemulsification and trabeculotomy by internal approach with a follow-up to 21 months.Universities private practices in United States.This prospective interventional case series comprised 304 consecutive eyes open-angle glaucoma cataract having Trabectome (NeoMedix Inc.). The is designed open direct pathway for aqueous flow from anterior chamber into Schlemm canal collector channels. Under gonioscopic control, bipolar cautery was...
To determine the effect of a failed trabectome on outcomes subsequent trabeculectomy.A cohort study eyes that underwent trabeculectomy after procedure (study) compared with as an initial surgical (control). Inclusion criteria were open-angle glaucoma, age ≥18 years, and uncontrolled glaucoma maximally tolerated medical therapy. Exclusion concurrent surgery follow-up less than 6 months. Outcome measures intraocular pressure (IOP), success rate, occurrence complications. Failure was additional...
AbstractPurpose. The similar and overlapping activity of VEGF the potent corneal-derived angiogenic eicosanoid 12(R)-HETrE calls for a study temporal relationship in expression these two autocoids. Since recent evidence suggests that hypoxia induces CYP4B1 mRNA which might be involved conversion arachidonic acid to 12(R)-HETrE, we determined its time-dependent correlated it rabbit model closed eye contact lens-induced injury. Methods. Rabbit eyes were fitted with lenses followed by silk...
Purpose: To present available primary outcome results of global Trabectome experience for patients receiving procedure including cases with up to 90 months follow-up. Method: A total 5,435 were included in the study. Baseline demographics collected and measures intraocular pressure (IOP), number glaucoma medications secondary surgery, if any. Survival analysis was performed success defined as IOP ≤21 mmHg, at least 20 % reduction from baseline, no additional surgery. Results: At months,...
To evaluate the safety and efficacy of Trabectome after failed tube shunt surgery. Twenty patients with prior surgery who underwent alone were included. All had at least 3 months follow-up. Outcomes measured included intraocular pressure (IOP), glaucoma medications, secondary surgeries. The success for Kaplan–Meier survival analysis is defined as IOP ≤21 mm Hg, reduced by 20% from preoperative IOP, no Mean was 23.7 ± 6.4 Hg mean number medications 3.2 1.5. At 12 months, to 15.5 (P = 0.05)...
To determine the efficacy and safety of Trabectome surgery on patients with steroid response, ranging from ocular hypertension refractory to maximal medical therapy development steroid-induced glaucoma. A nonrandomized, nonblinded, retrospective study 20 subjects response was conducted. All eyes underwent alone. Nine had unremarkable visual field, 3 mild glaucoma, 8 advanced Outcome measures included intraocular pressure (IOP), number glaucoma medications, need for secondary surgery,...
The main goal of surgical glaucoma treatment is to reduce the intraocular pressure. standard procedure over past 40 years has been trabeculectomy, first described in 1968. This comes with a very high risk profile, and results moderate long-term at best. Tube shunt devices were introduced as an alternate means divert fluid out glaucomatous eye, attempting improve upon poor outcomes particularly refractory cases that had failed attempts prior surgeries. They are currently available handful...
To our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials different prostaglandin class drugs following uncomplicated phacoemulsification intraocular lens implantation. Despite multiple reports individual (PG) analogues being suggested as cause CME, there no recommendations regarding withholding these medications in perioperative period. Our patient OD 4-months post cataract extraction. XALATAN (Latanoprost) had been...
Coleman, Anne L MD, PhD; Mosaed, Sameh MD; Kamal, Deborah FRCOphth Author Information
To evaluate the association between office-hour central corneal thickness (CCT) and 24-hour intraocular pressure (IOP) fluctuation in patients with glaucoma.Observational case-control study.Measurements of IOP were obtained every 2 hours during a period from 52 untreated glaucoma 29 age-matched normal control subjects housed sleep laboratory. Habitual measurements using pneumatonometer sitting positions diurnal/wake (7 AM to 11 PM) supine position nocturnal/sleep (11 PM 7 AM). CCT was...
The purpose of this study was to report a novel case drug-induced angle-closure from aripiprazole (Abilify), an atypical antipsychotic, and propose mechanism for association.We 45-year-old white woman who presented in subacute angle closure 2 months after initiating 5 mg daily depression. This patient reported no prior ocular history had been on longstanding duloxetine (Cymbalta) 60 over 10 years before starting aripiprazole. Examination at initial presentation revealed intraocular pressure...
Latanoprost, and other prostaglandin analogs, have been previously associated with increased pigmentary reactions on the periocular skin. Here, we present a patient paradoxical depigmentation of skin within 1 year latanoprost use in both eyes. This report is first to document such an association, clinicians should be aware this adverse effect monitor for signs accordingly.
Importance The loss of vision following Boston Keratoprosthesis (BKPro) surgery due to glaucoma occurs at a high frequency as diagnosis and management after this procedure pose challenges. Objective To compare visual outcomes in patients undergoing with without prior or concurrent surgery. Design, setting, participants This is retrospective, observational cohort study who underwent Type I 19 eyes 18 had undergone BKPro met the inclusion criteria were identified. Twelve received (Group 1),...
Purpose: To evaluate outcomes of new adopters the OMNI ® Surgical System (Sight Sciences, Inc.) by prospectively evaluating intermediate-term patients operated trainees. Patients and Methods: This was a prospective study surgeries performed trainees on with open angle glaucoma undergoing simultaneous cataract surgery ab interno canaloplasty trabeculotomy using System. Pre-operative intraocular pressure (IOP) number medications were recorded. Only minimum 6-month follow up included. Baseline...