A5101460185- Shoulder Injury and Treatment
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Immune cells in cancer
- Shoulder and Clavicle Injuries
- Cardiac Valve Diseases and Treatments
- Immunotherapy and Immune Responses
- Colorectal Cancer Screening and Detection
- Smoking Behavior and Cessation
- Gallbladder and Bile Duct Disorders
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Glaucoma and retinal disorders
- Celiac Disease Research and Management
- CAR-T cell therapy research
- Injury Epidemiology and Prevention
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Pancreatitis Pathology and Treatment
- Genomics and Rare Diseases
- Obesity, Physical Activity, Diet
- Opioid Use Disorder Treatment
The Ohio State University
2024-2025
University of Pennsylvania
2021-2024
Mayo Clinic in Florida
2021-2024
Mayo Clinic
2024
Australian National University
2024
UCLA Health
2017-2024
Icahn School of Medicine at Mount Sinai
2024
Pennsylvania Hospital
2024
Mayo Clinic in Arizona
2023-2024
Penn State Milton S. Hershey Medical Center
2023
Gingipains from Porphyromonas gingivalis drive Alzheimer’s pathology and can be blocked with small-molecule inhibitors.
In Appalachia, youth tobacco-use rates remain higher than the U.S. national average. Past research has indicated that several factors are related to high of tobacco use among Appalachian (e.g. low socioeconomic status, rural lifestyles). Of states, Kentucky one highest use. The aim this study was explore views living in counties.In Fall 2014 - Spring 2015, focus group interviews were conducted with middle and school students (N=109) counties Kentucky. Each session included open-ended...
Background and Aims: The results of class prediction the determination prognostic markers in diffuse large B-cell lymphoma (DLBCL) have been variably reported. Apart from biological variations, this may be caused by differences laboratory techniques, scoring definitions inter- intra-observer variation. In study, an international collaboration clinical research groups has concentrated on validation standardisation immunohistochemistry currently potentially interesting DLBCL. Methods: Sections...
BackgroundFew data are available on the supply and consumption of nutrients at country level. To address this gap, we aimed to create a database that provides information availability (ie, supply) 156 across 195 countries territories from 1980 2013.MethodsWe matched 394 food agricultural commodities Food Agriculture Organization United Nations Supply Utilization Accounts (SUAs) items in States Department Composition Database obtained nutrient composition SUAs' items. Then, after adjusting...
Immunotherapeutic herpes simplex virus 2 (HSV-2) vaccine efficacy depends upon the promotion of antigen-specific immune responses that inhibit reactivation or reactivated virus, thus controlling both recurrent lesions and viral shedding. In present study, a candidate subunit vaccine, GEN-003/MM-2, was evaluated for its ability to induce broad-spectrum response in mice therapeutic HSV-2-infected guinea pigs. GEN-003 is comprised HSV-2 glycoprotein D2 (gD2ΔTMR340-363) truncated form infected...
Background MicroRNAs are small non-coding RNAs involved in the regulation of gene expression on a posttranscriptional level. These regulatory have been implicated numerous cellular processes and further deregulated different cancer types, including breast cancer. MiR-92a is part miR-17∼92 cluster, which was first reported to be linked tumourigenesis. However, little known about miR-92a potential associations tumour properties. The therefore characterized 144 invasive samples using situ...
Endoscopist fatigue potentially impacts colonoscopy. Fatigue is difficult to quantitate, but polyp detection rates between non-fatigued and fatigued time periods could represent a surrogate marker. We assessed whether timing variables impacted at busy tertiary care endoscopy suite.Consecutive patients undergoing colonoscopy were retrospectively identified. Indications, clinical demographics, pre-procedural, procedural extracted from chart review; findings determined the procedure reports....
The cellular microenvironment in follicular lymphoma is of biological and clinical importance. Studies on the significance non-malignant cell populations have generated conflicting results, which may partly be influenced by poor reproducibility immunohistochemical marker quantification. In this study, manual scoring automated microscopy based a tissue microarray 25 lymphomas as compared to flow cytometry evaluated. agreement between was moderate for CD3, low CD4, high CD8, with some...
Gene expression studies have identified the microenvironment as a prognostic player in diffuse large B-cell lymphoma. However, there is lack of simple immune biomarkers that can be applied clinical setting and could helpful stratifying patients. Immunohistochemistry has been used for this purpose but results are inconsistent. We decided to reinvestigate its impact using immunohistochemistry, with two systems image analysis, set patients Diagnostic tissue from 309 was arrayed onto...
Abstract Background The healthcare burden posed by the coronavirus disease 2019 (COVID‐19) pandemic in New York Metropolitan area has necessitated postponement of elective procedures resulting a marked reduction cardiac catheterization laboratory (CCL) volumes with potential to impact interventional cardiology (IC) fellowship training. Methods We conducted web‐based survey sent electronically 21 Accreditation Council for Graduate Medical Education accredited IC program directors (PDs) and...
We used graph theoretical measures to investigate the hypothesis that structural brain connectivity constrains influence of functional on relation between age and fluid cognition. Across 143 healthy, community-dwelling adults 19-79 years age, we estimated network properties from diffusion-weighted imaging resting-state magnetic resonance imaging. confirmed previous reports age-related decline in strength efficiency networks, as well within modules. Functional contrast, exhibited only system...
We propose to examine how attention disparities between retail and institutional investors affect market resiliency through their trading patterns across overnight intraday periods. Using U.S. equity data from 2010-2024, we will employ panel regressions test whether intense tug-of-war periods, particularly during high episodes, lead lower due arbitrageurs' overcorrection of perceived mispricing. expect these effects be more pronounced macroeconomic announcements that differentially capture...
Videos promoting electronic cigarettes (e-cigarettes) can be easily accessed on YouTube. Marketing claims present in YouTube videos may help shape the public's opinion of e-cigarettes. Thus, it is important to understand most frequent marketing and video sources.The objectives this study were 1) identify that are commonly made e-cigarette retail websites 2) compare frequency user-generated professional videos. Through content analysis, evaluated six descriptive information about (n = 50)...
// Rebecca Ward 1 , Andrew H. Sims 2 Alexander Lee Christina Lo Luke Wynne Humza Yusuf Hannah Gregson Michael P. Lisanti Federica Sotgia Göran Landberg 1,3 and Lamb Breakthrough Breast Cancer Unit, Institute of Sciences, Paterson for Research, University Manchester, UK Applied Bioinformatics Cancer, Edinburgh Research Centre, Carrington Crescent, Edinburgh, 3 Sahlgrenska Center, Gothenburg, Sweden Correspondence to: Lamb, email: Keywords : macrophage, breast, stem-cells, migration Received...
Background Guidelines promote shared decision-making (SDM) for anticoagulation in patients with atrial fibrillation. We recently showed that adding a within-encounter SDM tool to usual care (UC) increases patient involvement and clinician satisfaction, without affecting encounter length. aimed estimate the extent which use of an changed adherence decided plan clinical safety end points. Methods Results conducted multicenter, encounter-level, randomized trial assessing efficacy UC versus...