A5052840922- Analytical chemistry methods development
- Effects and risks of endocrine disrupting chemicals
- Mass Spectrometry Techniques and Applications
- Toxic Organic Pollutants Impact
- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Chromatography
- Mercury impact and mitigation studies
- Electrochemical Analysis and Applications
- Carcinogens and Genotoxicity Assessment
- Metabolomics and Mass Spectrometry Studies
- Phytoestrogen effects and research
- Estrogen and related hormone effects
- Microfluidic and Bio-sensing Technologies
- Advanced Chemical Sensor Technologies
- Nanoparticles: synthesis and applications
- Marine Biology and Environmental Chemistry
- Air Quality and Health Impacts
- Chemical Analysis and Environmental Impact
- Nanopore and Nanochannel Transport Studies
- DNA and Nucleic Acid Chemistry
- Atmospheric chemistry and aerosols
- Protein Hydrolysis and Bioactive Peptides
- Heavy Metal Exposure and Toxicity
- Indoor Air Quality and Microbial Exposure
- Ion-surface interactions and analysis
Health Canada
2014-2024
University of Mary
2012
Queen's University
2006
National Academies of Sciences, Engineering, and Medicine
2001-2003
National Research Council Canada
2002
Saitama University
1998
Analysis and Testing Centre
1994
Non-targeted analysis (NTA) encompasses a rapidly evolving set of mass spectrometry techniques aimed at characterizing the chemical composition complex samples, identifying unknown compounds, and/or classifying without prior knowledge regarding content samples. Recent advances in NTA are result improved and more accessible instrumentation for data generation tools evaluation interpretation. As researchers continue to develop approaches various scientific fields, there is growing need...
The present study investigated the levels of phthalate esters in a total 86 human milk samples collected among 21 breast-feeding mothers over 6-month postpartum time. Di(2-ethylhexyl) (DEHP) was predominant ester with arithmetic mean value 222 ng g-1 (range: 156−398 g-1, 95% confidence limit), followed by dibutyl (DBP), 0.87 0.62−1.2) g-1. Diethyl (DEP), 0.31 detected only small number samples. Weak correlations between lipid content and were observed. fluctuated period; this may indicate...
A modified Bergener parallel path nebulizer was used for the generation of volatile metal species Pt, Co, Ag, Cu, Rh, Pd, Au, Ni, Ir, Ti and Mn through reaction with tetrahydroborate (III). Several physicochemical factors were identified which impact on their yield which, at present, is estimated to range from 0.02-2% absolute.
The mechanisms of chemical vapor generation (CVG) transition and noble metals by reaction with tetrahydroborate(III) have been investigated in an effort to reconcile fundamental properties compounds containing metal–hydride bonds the experimental evidence collected present work recent analytical literature on CVG. Silver, gold rhodium were detail. Various materials constituting wetted surfaces apparatus (Ryton, glass, silanized glass) examined for their effect overall process, as was...
The vapor generation characteristics of several transition and noble metals arising from reduction their aquo-ions by tetrahydroborate(III) are presented. A modified parallel path Burgener Teflon nebulizer interfaced to an ICP-MS for detection was used examine the effects experimental variables. influence both hydrochloric nitric acid as well nature surface exposed nascent species is paramount importance overall efficiency process. Both glass Ryton double pass spray chambers were examined,...
Generation of atomic and molecular species cadmium following reaction acidified sample with sodium tetrahydroborate reductant using a modified parallel path Burgener nebulizer has been accomplished. Once generated, are stable in water, having half-life 2.2 min, can be preconcentrated for subsequent quantitation. Although the initial products reduction appear to free atoms, interaction nascent hydrogen gives rise hydride transformation moderated by chemistry surface groups exposed products....
A new on-line capillary zone electrophoresis/mass spectrometry (CZE/MS), constant pressure-assisted electrokinetic injection (PAEKI), for the analysis of negatively charged nucleotides is reported. PAEKI uses an applied pressure to counterbalance reverse electroosmotic flow in column during sample injection, while taking advantage field amplification medium. At balance, running buffer stationary, permitting potentially unlimited time, and hence enrichment power. The ability maintain a narrow...
Intermediate volatile organic compounds (IVOCs) have recently been characterized for their contributions to the formation of secondary aerosol in atmospheric air. However, IVOCs air various indoor environments not yet. In this study, we and measured IVOCs, (VOCs) semi-volatile (SVOCs), residential Ottawa, Canada. including n-alkanes, branched-chain alkanes (b-alkanes), unspecified complex mixtures (UCM) oxygenated (such as fatty acids), were found a large impact on quality. The results...
Phthalates are a group of chemicals used in variety products worldwide.
Phthalates are a group of compounds widely used in consumer products and they ubiquitous the environment due to their widespread commercial use.
Electrophoresis characteristics of several monophthalates in the sample zone and EOF variation a fused-silica capillary column during constant pressure-assisted electrokinetic injection (PAEKI) an on-line CE-MS were studied effort to reconcile mobility theory field amplification with enhancement achieved present work. Influences length on amount injected using PAEKI investigated detail except for time, was found increase linearly length. A longer provides linear time range injection. The...
Sample injection is a crucial step in CE. In past, many efforts have been focused on concentrating the analytes into sharp sample plug. 2006, pressure-assisted electrokinetic (PAEKI) was proposed as new preconcentration technique for anions. this study, we expanded applicability of PAEKI to online preconcentrate positively charged analytes. L-Arginine, L-lysine, and imidazole were chosen target method development. The enhancement factor over 3000-fold. When CZE coupled with Q-TOF system,...
Methyl mercury (MeHg) is a common contaminant worldwide. Health authorities keep monitoring MeHg levels in biological and environmental samples to assess the corresponding exposure population. So far, basic leaching has been mostly used for extraction. In this study, it was demonstrated that methanesulfonic acid, commonly amino acid extraction, can be Species-specific isotope dilution employed achieve accurate results. The method validated by analysis of dogfish liver certified reference...
The application of functional imaging tools and techniques on the molecular level enables investigators to characterize structures biomolecules interactions between biomolecules. characterization recognition events with atomic force microscopy (AFM) is a new methodology in biological research. Recent advances field scanning probe especially have made it possible discover dynamic systems self-assembly quantify forces proteins. interaction mechanisms were explored by many researchers tackle...