A5076746724- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Atmospheric chemistry and aerosols
- Water Quality Monitoring and Analysis
- Analytical chemistry methods development
- Pesticide Residue Analysis and Safety
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Sensors
- Effects and risks of endocrine disrupting chemicals
- Atmospheric Ozone and Climate
- Various Chemistry Research Topics
- Protein purification and stability
- Electrochemical Analysis and Applications
- Health, Environment, Cognitive Aging
- Chemistry and Stereochemistry Studies
- Atmospheric and Environmental Gas Dynamics
- Astronomical and nuclear sciences
- Cardiovascular and exercise physiology
- Ginkgo biloba and Cashew Applications
- Engineering and Material Science Research
- Biosimilars and Bioanalytical Methods
- bioluminescence and chemiluminescence research
National Institute of Standards and Technology
2014-2024
Material Measurement Laboratory
2014-2024
National Institute of Standards
2018-2024
Oregon State University
2011-2016
University of Toronto
2016
Aqueous film-forming foams (AFFFs) are a vital tool to fight large hydrocarbon fires and can be used by public, commercial, military firefighting organizations. In order possess these superior capabilities, AFFFs contain fluorochemical surfactants, of which many the chemical identities listed as proprietary. Large-scale controlled (e.g., training activities) uncontrolled releases AFFF have resulted in contamination groundwater. Information on composition formulations is needed fully define...
Non-targeted analysis (NTA) encompasses a rapidly evolving set of mass spectrometry techniques aimed at characterizing the chemical composition complex samples, identifying unknown compounds, and/or classifying without prior knowledge regarding content samples. Recent advances in NTA are result improved and more accessible instrumentation for data generation tools evaluation interpretation. As researchers continue to develop approaches various scientific fields, there is growing need...
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies facilitate widespread integration of the MAM platform, which is an emerging ultra-high-performance liquid chromatography–mass spectrometry application. Successful implementation purity-indicating assay requires new peak detection (NPD) potential process- and/or product-related impurities. NPD interlaboratory study described herein...
Abstract. A growing number of ambient measurements isocyanic acid (HNCO) are being made, yet little is known about its fate in the atmosphere. To better understand HNCO's loss processes and particularly atmospheric partitioning behaviour, we measure effective Henry's Law coefficient KHeff with a bubbler experiment using chemical ionization mass spectrometry as gas phase analytical technique. By conducting experiments at different pH values temperature, KH 26 ± 2 M atm−1 obtained, an enthalpy...
Access to clean water is a vitally important part of the lives all people, yet there often concern about contamination by heavy metals. The detection and measurement metals in can be performed using colorimetric reagents paired with ultraviolet–visible light (UV–vis) spectrophotometry. presented activity includes construction simple, inexpensive single-wavelength spectrophotometer LEDs as source detector. Using reagent, 2,4,6-tripyridyl-s-triazine, concentration iron measured LED...
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted traditional peptide mapping methods; it leverages mass spectrometry (MS) detection confident identification quantitation of many types attributes may be targeted monitoring. While has widely explored across the industry, yet gain strong foothold within QC...
ADVERTISEMENT RETURN TO ISSUEPREVViewpointNEXTSpeaking the Same Language: The Need for Accurate and Consistent Reporting of Novel Per- Polyfluoroalkyl SubstancesBenjamin J. Place*Benjamin PlaceChemical Sciences Division, National Institute Standards & Technology, Gaithersburg, Maryland 20850, United States*Phone: 301-975-3941; email: [email protected]More by Benjamin PlaceView Biographyhttps://orcid.org/0000-0003-0953-5215 Jared M. RaglandJared RaglandChemical Charleston, South Carolina...
ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionORIGINAL ARTICLEThis notice is a correctionCorrection to Identification of Novel Fluorochemicals in Aqueous Film-Forming Foams Used by the US MilitaryB. J. Place and A. Field*Cite this: Environ. Sci. Technol. 2012, 46, 19, 10859Publication Date (Web):September 17, 2012Publication History Published online17 September 2012Published inissue 2 October 2012https://pubs.acs.org/doi/10.1021/es303627khttps://doi.org/10.1021/es303627kcorrectionACS...
Abstract. A growing number of ambient measurements isocyanic acid (HNCO) are being made, yet little is known about its fate in the atmosphere. To better understand HNCO's loss processes and particularly atmospheric partitioning behavior, we measure effective Henry's Law solubility coefficient KHeff with a bubbler experiment using chemical ionization mass spectrometry as gas phase analytical technique. By conducting experiments at different pH values temperature, KH 26 ± 2 M atm-1 obtained,...
The success of nontargeted analysis often depends on libraries containing reference mass spectra known chemical compounds; the unknown compounds are compared to these spectra, leading a probable compound identity. Typical calculations include mean measured values for each ion m/z and intensity with no estimation variability measurement. This study presents novel tool calculation spectrum, including various data parameters that can impact variability. Using perfluorooctanoic acid (PFOA) as...
Sulfonephthalein pH indicator dyes have historically been noted for impurities originating from the synthesis process, which lead to batch differences in measurements. Uncertainties up 0.1 units attributed these reagents. In an effort understand extent of and potential impact on expanded uncertainty spectrophotometric measurements, we examined seven commercially available sulfonephthalein indicators using liquid chromatography-mass spectrometry (LC-MS): bromocresol green (BCG), purple (BCP),...
Nontargeted analysis (NTA) is a rapidly growing field of techniques that includes the identification unknown chemical analytes in complex mixtures such as environmental, biological, and food matrices. The use reference mass spectral databases key component most NTA workflows, providing high level confidence for when analytical standards are not available, yet effective interlaboratory sharing research grade spectra remains challenging. Database Infrastructure Mass Spectrometry (DIMSpec)...