A5087717382- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Air Quality and Health Impacts
- Atmospheric chemistry and aerosols
- Effects and risks of endocrine disrupting chemicals
- Chemical Analysis and Environmental Impact
- Fish Ecology and Management Studies
- Prenatal Substance Exposure Effects
- Estrogen and related hormone effects
- Methemoglobinemia and Tumor Lysis Syndrome
- Heavy Metal Exposure and Toxicity
- Aquaculture disease management and microbiota
- Parasite Biology and Host Interactions
- Cytokine Signaling Pathways and Interactions
- Birth, Development, and Health
- Aquatic Ecosystems and Biodiversity
- Fluoride Effects and Removal
- Health, Environment, Cognitive Aging
- Retinoids in leukemia and cellular processes
- Metabolomics and Mass Spectrometry Studies
- Soil and Water Nutrient Dynamics
- Groundwater flow and contamination studies
- Fish Biology and Ecology Studies
- Water Quality and Resources Studies
Arcadis (United States)
2022-2025
Oak Ridge Institute for Science and Education
2021-2024
Oak Ridge Associated Universities
2021-2024
North Carolina State University
2018-2022
Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Environmental monitoring revealed high concentrations hexafluoropropylene oxide dimer acid (HFPO-DA) other novel PFAS lower Cape Fear River; however, there is limited information on exposures effects this contamination aquatic biota. Serum 23 Striped Bass (Morone saxatilis) from River (n = 58) a reference population an aquaculture laboratory Pamlico/Tar watershed 29) were...
Infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) was coupled with high-resolution accurate-mass-mass spectrometry (HRAM-MS) to image perfluoroalkyl and polyfluoroalkyl substances (PFAS) in stabilized soil cores. Previous field-scale research demonstrated a substantial decrease the leachability of PFAS following application situ stabilization solidification (S/S) an aqueous film-forming foam (AFFF) source zone. While this previous study empirically confirmed...
Central North Carolina (NC) is highly contaminated with per- and polyfluoroalkyl substances (PFAS), in part due to local fluorochemical production. Little known about the exposure profiles long-term health impacts for humans animals that live nearby communities. In this study, serum PFAS concentrations were determined using liquid chromatography high-resolution mass spectrometry diagnostic clinical chemistry endpoints assessed 31 dogs 32 horses reside Gray's Creek NC at households documented...
Surface and groundwater of the Cape Fear River basin in central coastal North Carolina is contaminated with high levels per- polyfluoroalkyl substances (PFAS). Elevated PFAS have also been found blood fish wildlife from River, human populations reliant on well or surface water as a source drinking water. While public environmental health impacts long-term exposures are poorly understood, elevated concentrations some linked immunotoxicity increased incidence chronic autoimmune diseases...
Fire suppression systems are known to be impacted with residual, entrained per- and polyfluoroalkyl substances (PFASs) because of historical use aqueous film forming foam (AFFF) fluoroprotein foam. Amphiphilic PFASs aggregate at liquid:solid interfaces creating a hydrophobic layer which reduces the effectiveness water remove PFAS from layered surfaces. When fire transitioned fluorine free (F3) without appropriate cleaning, residual associated surfaces system can contaminate replacement F3....
Abstract There is compelling evidence that developmental exposure to toxic metals increases risk for obesity and obesity-related morbidity including cardiovascular disease type 2 diabetes. To explore the hypothesis Cd of later in life, male, female CD-1 mice were maternally exposed 500 ppb CdCl2 drinking water during a human gestational equivalent period (gestational day 0-postnatal 10 [GD0-PND10]). Hallmark indicators metabolic disruption, hepatic steatosis, syndrome evaluated prior birth...
The recent application of non-targeted analysis (NTA) techniques in environmental monitoring has revealed numerous novel fluorinated species surface water, wildlife, and humans the Cape Fear River (CFR) region North Carolina. In this study, we have re-examined archived alligator, striped bass, horse, dog serum as well various seabird tissue data from previously reported exposure studies order to extend panel detected PFAS. compounds PFO6, PFO7, PFO8, Nafion byproduct 6 (NBP6) were for first...
When fire suppression systems that held aqueous film forming foams (AFFF) are transitioned to per- and polyfluoroalkyl substance (PFAS)-free firefighting formulations, PFAS can dissolve from the wetted surfaces of release into new formulations. The overall objective this work was characterize residual mass on aircraft rescue (ARFF) vehicle on-board system components water, mixed foam concentrate with various geometries, materials construction, locations within system. ARFF were dismantled...
Abstract Pansteatitis is the leading cause for decline in Nile crocodile populations and sporadic mortality of fish Olifants River System, South Africa. To determine prevalence this disease lentic systems, Mozambique tilapia, Oreochromis mossambicus , were collected from Lake Loskop, Flag Boshielo, Phalaborwa Barrage Luphephe‐Nwanedi. The former three impoundments are located within main stem River, while latter, which geographically isolated situated Limpopo served as a reference site....
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Abstract Surface and ground water of the Cape Fear River basin in central coastal North Carolina is contaminated with high levels per- polyfluoroalkyl substances (PFAS). Elevated PFAS have also been found blood fish wildlife living around River, human populations reliant on well or surface from as a sources drinking water. While public environmental health impacts long-term exposures are poorly understood, elevated concentrations some linked immunotoxicity increased incidence chronic...