- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Speech and Audio Processing
- Noise Effects and Management
- Ear Surgery and Otitis Media
- Vestibular and auditory disorders
- Obstructive Sleep Apnea Research
- Hearing Impairment and Communication
- Dysphagia Assessment and Management
- Phonetics and Phonology Research
- Phonocardiography and Auscultation Techniques
- Glutathione Transferases and Polymorphisms
- Tracheal and airway disorders
- Neonatal and fetal brain pathology
- Neuroscience of respiration and sleep
- Ear and Head Tumors
- Head and Neck Cancer Studies
- Face recognition and analysis
- Second Language Acquisition and Learning
- Subtitles and Audiovisual Media
- Speech and dialogue systems
- Dietary Effects on Health
- Oropharyngeal Anatomy and Pathologies
- Cancer Risks and Factors
- Face and Expression Recognition
National Cheng Kung University Hospital
2010-2024
National Cheng Kung University
1998-2014
Alcohol consumption is an established risk factor for head and neck cancer (HNC). The major carcinogen from alcohol acetaldehyde, which may be produced by humans or oral microorganisms through the metabolism of ethanol. To account different sources acetaldehyde production, current study examined interplay between consumption, hygiene (as a proxy measure growth microorganisms), alcohol-metabolizing genes (ADH1B ALDH2) in HNC. We found that both fast (*2/*2) slow (*1/*1+ *1/*2) ADH1B genotypes...
Sleep disturbance and psychological distress are among the most prevalent comorbidities of tinnitus. We aimed to clarify dose-response effects these phenomena with tinnitus severity.This study enrolled adult patients subjective for more than 6 months was conducted from January 2017 December 2018 in one tertiary medical center local hospital. Data collected included demographic data questionnaires, namely Tinnitus Handicap Inventory (THI), Pittsburgh Quality Index (PSQI), Epworth Sleepiness...
To compare tone discrimination, speech perception, and general listening benefit in Mandarin-speaking children using standard HiRes after 1, 3, 6 months of 120 use. The HiResolution Bionic Ear is an implantable prosthesis designed to provide access sound improve perception via electrical stimulation the auditory nerve. newest sound-processing strategy with Fidelity (HiRes 120). In 120, input signal analyzed greater spectral detail than original achieve a maximum bands. expected more because...
Abstract Objective Squamous cell carcinoma (SCC) of the external auditory canal (EAC) is a rare malignancy with various treatment strategies and outcomes. The purpose this study was to evaluate clinical characteristics survival outcomes identify prognostic factors in patients SCC EAC. Methods Twenty‐one EAC treated single tertiary center between 2009 2021 were retrospectively reviewed analyzed. modified Pittsburgh classification system applied for staging. Factors associated identified by...
Objectives In order to understand the communicative abilities of hearing impaired children in noisy situations and their communication problems, this study was undertaken examine speech recognition at different background noise levels, compare how context cues affect recognition. Methods Thirty-four with severe/profound impairment were enrolled. Fifteen had cochlear implants (CIs) 19 used aids (HAs). The Mandarin Speech Perception Noise (SPIN) test performed under two levels noise,...
To investigate the lingual artery (LA) position in tongue base through intraoperative ultrasound (IOU) imaging during transoral robotic surgery (TORS) and evaluate bleeding complications with or without assistance of IOU.Cohort study historical control.Patients obstructive sleep apnea (OSA) who underwent TORS for resection were recruited since 2016. During surgery, was employed to identify anatomic parameters LA base, including distance midline arterial depth diameter.Ninety-three OSA...
In this study we assessed the interaction between glutathione S-transferase (GST) genetic polymorphisms and noise exposures, with regard to their effect on hearing threshold levels for high frequencies (HTLHF). Research participants comprised 347 male workers, each participant’s cumulative exposure was determined using a job–exposure matrix. Approximately 64.6% of participants’ in Leq-8 h above 90 dBA. The mean HTLHF 32.1 dB. A significant dose–response relationship found HTLHF. We further...
Although substantial evidence supports a 20–30% risk reduction of colon cancer, breast and endometrial cancer by physical activity (PA), the for head neck (HNC) is limited. Three published studies on association between PA HNC have generated inconsistent results. The current study examined recreational (RPA) with more detailed assessment intensity, frequency, duration, total years RPA. Data RPA were collected from 623 cases 731 controls in-person interview using standardized questionnaire....
This observational study assessed sleep disturbance and autonomic dysfunction as risk factors for chronic subjective tinnitus through polysomnography (PSG) function tests.Adult patients with who visited the department of otolaryngology in our hospitals (n = 40), along controls without 80), were recruited. Individuals an average hearing threshold level (HL) exceeding 25 dB HL a known diagnosis insomnia excluded. Objective assessments comprised pure-tone audiometry, PSG, tests (e.g., cold...
Introduction: Cochlear implantation is an effective treatment for children with deafness. Although the binaural effect of bilateral cochlear on sound localization and speech perception in noisy environments has been demonstrated, outcome performance predictors second implant (CI2) remain uncertain patients receiving sequential implantation. This study evaluated hearing between first (CI1), CI2, implants (CI1+2) among Methods: single-center retrospective enrolled 14 adolescents aged 8–18...
Articulation problems seriously reduce speech intelligent and communication affect person's interpersonal communication, personality, social adaptive capacity, learning ability. In the clinical protocol, language therapist utilizes experience to individualized assessment, treatment, training. However, manpower of therapists assistant instruments are insufficient. this paper, an articulation assessment training system is proposed assist disorders. The errors in phonetic analyzed modeled by...
Articulation training with many kinds of stimulus and messages such as visual, voice, articulatory information can teach user to pronounce correctly improve user's ability. In this paper, an articulation system intelligent interface multimode feedbacks is proposed the performance training. Clinical knowledge speech evaluation used design dependent network. Then, automatic recognition network applied identify pronunciation errors. Besides, hierarchical Bayesian recognize emotion from...
Recessive variants in the MYO15A gene constitute an important cause of sensorineural hearing impairment (SNHI). However, clinical features MYO15A-related SNHI have not been systemically investigated. This study aimed to delineate and outcomes patients with pathogenic variants.This recruited 40 biallelic from 31 unrelated families. The were grouped based on presence N-terminal domain (N variants). longitudinal audiological data for those undergoing cochlear implantation, auditory speech...
The performance of hearing aids would be seriously reduced by nonstationary noises. In this paper, forward-backward minima controlled recursive averaging is proposed to improve the speech intelligibility reducing components A estimation developed correctively track noises, especially beginning To suppress these a log-spectral amplitude estimator was selected as gain function and used effectively estimate power spectrum Moreover, harmonic regeneration integrated reduce overestimation...
This study aimed (1) to demonstrate the efficacy of balloon dilation Eustachian tuboplasty (BDET) for dilatory tube dysfunction (ETD) and (2) determine whether adjunctive ventilation insertion (VTI) is superior myringotomy in relieving symptoms patients with ETD concurrent middle ear effusion (MEE) treated BDET.A retrospective cohort study.Tertiary care academic center.Patients undergoing BDET a ≥6-month follow-up period were enrolled evaluated mainly using function (ETF) tests Tube...
Abstract Aim To determine the risk patterns associated with transient hearing impairment (THI) and permanent loss (PHL) of infants born very preterm who failed screenings. Method We enrolled 646 (347 males, 299 females) at no more than 30 weeks' gestation between 2006 2020 received auditory brainstem response screening term‐equivalent age. Audiological examinations revealed THI, when normalized, or PHL, defined as a persistent unilateral bilateral threshold above 20 dB. Principal component...
The results of the study suggest that age implantation was an important predicting factor speech intelligibility, articulation ability and voice in prelingually deafened children with cochlear implantation. receptive language level preimplantation also a intelligibility except measurement. Therefore, current suggested surgery at early could enhance overall speech-production abilities.
The assistive hearing devices are the only aids to help subjects with loss use their residual hearing. However, performance of those is closely dependent on auditory training. To develop handheld based personal training system perceptional discrimination analysis and automatic test item generation very helpful for loss. Besides, it would ease burden speech-language pathologists in developing a In this study, mel-frequency cepstrum coefficients speech recognition applied objectively estimate...
Objectives/Hypothesis Transoral robotic surgery (TORS) in the base of tongue (BOT) reduction has been shown to decrease apnea‐hypopnea index (AHI) and improve daytime sleepiness obstructive sleep apnea (OSA) patients. Intraoperative ultrasound (IOU) can be employed guide prevent massive bleeding. Study Design Cohort study with historical control. Methods A cohort compare outcomes between OSA patients who received TORS without IOU assistance. Results From 2016 2019, this enrolled 80 underwent...