A5009440657- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Circular RNAs in diseases
Shandong First Medical University
2024
Shandong Tumor Hospital
2024
Abstract Background Tumor-derived exosomal miRNAs play crucial roles in cancer diagnosis. Current studies aim to identify associated with colorectal (CRC) that are noninvasive, sensitive, and specific. Patients methods Exosomes were extracted from CRC patients healthy donors via ultracentrifugation, followed by verification transmission electron microscopy (TEM), qNano, Western blot analysis. The differential expression levels clinical characteristics of miR-205-5p analyzed data Cancer...
Abstract Colorectal cancer is a common malignant tumor, whose growth and metastasis are influenced by numerous factors. MicroRNAs have garnered increasing attention in recent years due to their involvement tumor development. Exosomes involved intercellular signaling influence development promoting cell proliferation through activation of angiogenesis other mechanisms. This study aimed investigate how the exosomes containing miR-320d from colorectal (CRC) cells promote regulating...