A5112468693- Reading and Literacy Development
- Epilepsy research and treatment
- Language Development and Disorders
- Cognitive and developmental aspects of mathematical skills
- Neurobiology of Language and Bilingualism
- Writing and Handwriting Education
- Attention Deficit Hyperactivity Disorder
- Genetics and Neurodevelopmental Disorders
- Neonatal and fetal brain pathology
- Developmental and Educational Neuropsychology
- French Language Learning Methods
- EEG and Brain-Computer Interfaces
- Sleep and Wakefulness Research
- Metabolism and Genetic Disorders
- Children's Physical and Motor Development
- Educational and Psychological Assessments
- Pharmacological Effects and Toxicity Studies
- Infant Development and Preterm Care
- Muscle Physiology and Disorders
- Text Readability and Simplification
- Psychology and Mental Health
- Psychoanalysis and Psychopathology Research
- Hemispheric Asymmetry in Neuroscience
- Tactile and Sensory Interactions
- Cerebrospinal fluid and hydrocephalus
Bicêtre Hospital
2008-2023
Association pour la Recherche de Thérapeutiques Innovantes en Cancérologie
2019-2022
Centre hospitalier Robert-Ballanger
2020
Assistance Publique – Hôpitaux de Paris
2002-2019
Ministère de la Culture
2016
Université Paris-Saclay
2012
Laboratoire de Psychologie et NeuroCognition
2003-2010
Université Paris Cité
2010
Economie Publique
2006
Centre Hospitalier du Pays d'Aix
2000
Background: The relationship between phoneme awareness, rapid automatized naming (RAN), verbal short‐term/working memory (ST/WM) and diagnostic category is investigated in control dyslexic children, the extent to which this depends on orthographic complexity. Methods: General cognitive, phonological literacy skills were tested 1,138 1,114 children speaking six different languages spanning a large range of complexity (Finnish, Hungarian, German, Dutch, French, English). Results: Phoneme...
Children's cognitive abilities and school achievements are deeply affected by parental socioeconomic status (SES). Numerous studies have reported lower performance in relation to unfavorable environments, but little is known about the effects of SES on child's neural structures. Here, we systematically explore association between brain anatomy through MRI a group 23 healthy 10-year-old children with wide range SES. We confirm behaviorally that language one domains most Furthermore, observe...
Among the various asymmetrical structures of human brain, planum temporale, an anatomical region associated with a variety auditory and language-related processes, has received particular attention. While its surface area been shown to be greater in left hemisphere compared right about two-thirds general population, altered patterns asymmetry were revealed by post mortem analyses individuals developmental dyslexia. These findings have inconsistently replicated magnetic resonance imaging...
In this study, we concurrently investigated 3 possible causes of dyslexia-a phonological deficit, visual stress, and a reduced attention span-in large population 164 dyslexic 118 control French children, aged between 8 13 years old. We found that most children showed either in terms response accuracy (92.1% the sample), speed (84.8%), or both (79.3%). Deficits span, as measured by partial report ability, affected 28.1% participants, all which also deficit. Visual subjective reports...
We analysed the reading abilities and processing of 21 children with Duchenne muscular dystrophy (DMD), 11 matched suffering from spinal atrophy (SMA) 42 receiving normal education. The principal result observed was that DMD exhibited a age which significantly lower than SMA compared their chronological age. These learning disabilities were not related to deficit in non‐verbal performance intelligence, but psycholinguistic evaluation showed verbal especially Similarities Arithmetic WISC‐R...
Benign childhood epilepsy with centrotemporal spikes (BECTS) is regarded as a benign form of because its usually favorable outcome, in terms seizures. Eighteen children BECTS were studied neuropsychological and learning abilities: intellectual quotient, oral language (phonological production, naming skills, verbal fluency syntactic comprehension), drawing visuo-spatial visual selective attention, memory, reading, numeracy spelling. The mean IQ the population was within normal range, but...
<b><i>Objective:</i></b> To compare the safety and efficacy of add-on lamotrigine placebo in treatment children adolescents with partial seizures. <b><i>Background:</i></b> Add-on monotherapy is safe effective adults seizures, reports preliminary uncontrolled trials suggest similar benefits children. <b><i>Methods:</i></b> We studied 201 diagnoses seizures any subtype currently receiving stable conventional regimens antiepileptic therapy at 40 study sites United States France. After a...
Molecular study and neuropsychological analysis were performed concurrently on 49 patients with Duchenne muscular dystrophy (DMD) in order to find a molecular explanation for the cognitive impairment observed most DMD patients. Complete of dystrophin gene was define localization deletions duplications relation different promoters. Qualitative Dp71 transcript testing specific first exon Dp140 also carried out. Neuropsychological assessed verbal visuospatial intelligence, memory, reading...
Background: Reading impairment is the major learning disability in childhood. Most previous studies were done on English-speaking populations. Yet, it has been argued that English writing system exacerbates phonological deficits because of its exceptionally high inconsistency between spelling and sound. Thus, cross-language are needed to explore universal versus language-specific factors underlying reading impairment. The goal present research was study biological, socioeconomic, cognitive,...
Developmental dyslexia is a learning disability that specifically affects reading acquisition. Cortical anomalies and gray matter volume differences in various temporal regions have been reported dyslexic subjects compared with controls. However, consistency between studies lacking. In the present experiments, we focused our structural analyses on ventral occipitotemporal regions, defined by their functional response to visual categories. We applied subject-by-subject functionally guided...
Children's cognitive abilities and school achievements are deeply affected by parental socioeconomic status (SES).Numerous studies have reported lower performance in relation to unfavorable environments, but little is known about the effects of SES on child's neural structures.Here, we systematically explore association between brain anatomy through MRI a group 23 healthy 10-year-old children with wide range SES.We confirm behaviorally that language one domains most SES.Furthermore, observe...
Benign childhood epilepsy with centrotemporal spikes (BECTS) is a frequent, benign good prognosis. However, neuropsychological deficits have been reported during its active phase. In this study, we evaluate the long-term consequences of reputedly epilepsy, particularly relation between paroxysmal abnormalities and cerebral language lateralization. The outcomes concerning both overall cognitive lateral hemispheric functions were studied in twenty-three adolescents young adults total recovery...
The aim of this study was to determine the clinical, social, and/or professional and cognitive outcomes in adulthood continuous spike-waves during slow sleep (CSWS) Landau-Kleffner syndromes, which are two rare epileptic syndromes occurring children.We enrolled seven young adults, five who had a CSWS syndrome, two, syndrome childhood. We evaluated their intellectual level as well oral written language executive functions.This confirmed that epilepsy associated with these has good prognosis....
The impact of the prolonged use cetirizine at high dose (0.25 mg/kg twice a day over 18 mo) on behavior and cognitive ability was examined in double-blind, randomized, placebo-controlled trial (ETAC—Early Treatment Atopic Child) designed to establish whether it possible prevent young children (1–2 y old study entry) with atopic dermatitis from developing asthma. Well-validated standardized measures (Behavior Screening Questionnaire) cognition (McCarthy Scales Children's Abilities) were used....