Hyejung Han

ORCID: 0000-0002-1139-8929
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Dental Health and Care Utilization
  • Gut microbiota and health
  • Marine and coastal ecosystems
  • Marine Biology and Ecology Research
  • Dental Implant Techniques and Outcomes
  • Oral and gingival health research
  • Metabolomics and Mass Spectrometry Studies
  • HIV/AIDS oral health manifestations
  • Marine Toxins and Detection Methods
  • Bone health and treatments
  • Bone and Joint Diseases
  • Dental Radiography and Imaging
  • Probiotics and Fermented Foods

Pusan National University
2020-2025

Periodontitis is a chronic and multifactorial inflammatory disease that can lead to tooth loss. At present, the diagnosis for periodontitis primarily based on clinical examination radiographic parameters. Detecting periodontal pathogens at subgingival plaque requires skilled professionals collect samples. Periodontal are also detected various mucous membranes in patients with periodontitis. In this study, we characterized oral microbiome profiles from buccal mucosa supragingival space total...

10.3390/jcm9051549 article EN Journal of Clinical Medicine 2020-05-20

This study aimed to compare oral microbiome profiles between obese and lean individuals without clinical periodontitis, assess changes in the of subjects following bariatric surgery. Individuals with a body mass index (BMI) > 30 were enrolled group, whereas those BMI < 23 served as controls. The surgery which consented surgery, was followed up at 1, 3, 6 months examinations. Oral examinations conducted periodontal disease classified based on probing results. Saliva, buccal subgingival...

10.3389/fmicb.2025.1553404 article EN cc-by Frontiers in Microbiology 2025-03-18

The objective of this study was to analyze the microbial profile individuals with peri-implantitis (PI) compared those periodontally healthy (PH) subjects and periodontitis (PT) using Illumina sequencing.Buccal, supragingival, subgingival plaque samples were collected from 109 (PH: 30, PT: 49, PI: 30). V3-V4 region 16S rRNA sequenced analyzed microbiota.Microbial community diversity in PI group higher than other groups, 3 groups showed significantly separated clusters buccal samples....

10.5051/jpis.2202080104 article EN Journal of Periodontal & Implant Science 2022-08-17

Objective Next generation sequencing is commonly used to characterize the microbiome structure. MiSeq most analyze due its relatively long read length. Illumina also introduced 250 × 2 chip for NovaSeq. The purpose of this study was compare performance and NovaSeq in context oral study.

10.1080/20002297.2024.2344293 article EN cc-by-nc Journal of Oral Microbiology 2024-04-18

The study of the human microbiome is crucial for understanding disease mechanisms, identifying biomarkers, and guiding preventive measures. Advances in sequencing platforms, particularly 16S rRNA sequencing, have revolutionized research. Despite benefits, large reference databases (DBs) pose challenges, including computational demands potential inaccuracies. This aimed to determine if full-length data produced by PacBio could be used optimize DBs applied Illumina V3-V4 targeted microbial study.

10.3389/fmicb.2024.1485073 article EN cc-by Frontiers in Microbiology 2024-11-25

통영 연안 해역에서 chlorophyll-a 농도 변화 패턴과 그에 따른 식물플랑크톤 군집 변동을 파악하기 위해 62일간 연속 관측(2017년 7월 29일~9월 28일) 및 주 1~2회의 주기적인 분석을 실시하였다. 조사기간 동안 농도가 증감하는 변화가 3회 발생하였다. 첫 번째 변화(8월 6일~14일)에서는 14~16시 급격한 증가가 반복적으로 나타났으며, 이는 중 최우점종으로 출현한 와편모조류 Alexandrium affine의 일주수직운동에 의한 결과이다. 두 번째(8월 24일~30일) 세 번째(9월 12일~17일) 변화는 Chaetoceros curvisetus, Skeletonema marinoi-dohrnii complex등의 규조류에 의해 증가하였으며, 이때 규조류는 event 1의 A. 14~16시에 증가와 달리 특정 시간에 관계없이 증가하였다. 또한 실시간 농도의 관측을 통해 일주수직운동 특징적인 양상을 찾아냈으며, 3회의 농도에 대한 7~12일의 간격을 두고

10.7846/jkosmee.2018.21.2.107 article KO Journal of the Korean Society for Marine Environment & Energy 2018-05-25
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